Navigation Links
Newly discovered breast milk antibodies help neutralize HIV
Date:5/22/2012

DURHAM, N.C. Antibodies that help to stop the HIV virus have been found in breast milk. Researchers at Duke University Medical Center isolated the antibodies from immune cells called B cells in the breast milk of infected mothers in Malawi, and showed that the B cells in breast milk can generate neutralizing antibodies that may inhibit the virus that causes AIDS.

HIV-1 can be transmitted from mother to child via breastfeeding, posing a challenge for safe infant feeding practices in areas of high HIV-1 prevalence. But only one in 10 HIV-infected nursing mothers is known to pass the virus to their infants.

"That is remarkable, because nursing children are exposed multiple times each day during their first year of life," said senior author Sallie Permar, M.D., Ph.D., an assistant professor of pediatrics and infectious diseases at Duke. "We are asking if there is an immune response that protects 90 percent of infants, and could we harness that response to develop immune system prophylaxis (protection) during breastfeeding for mothers infected with HIV-1.

"Our work helped establish that these B cells in breast milk can produce HIV-neutralizing antibodies, so enhancing the response or getting more mucosal B-cells to produce those helpful antibodies would be useful, and this is a possible route to explore for HIV-1 vaccine development," Permar said.

The study was published on May 18 in PLoS One, an open-access journal published by the Public Library of Science.

"This is important work that seeks to understand what a vaccine must do to protect babies from mucosal transmission during breastfeeding," said Barton Haynes, M.D., co-author and a national leader in AIDS/HIV research, director of the Center for HIV/AIDS Vaccine Immunology (CHAVI), as well as director of the Duke Human Vaccine Institute (DHVI). "The antibodies isolated are the first HIV antibodies isolated from breast milk that react with the HIV-1 envelope
'/>"/>

Contact: Mary Jane Gore
mary.gore@duke.edu
919-660-1309
Duke University Medical Center
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Key proteins newly discovered form and function may provide novel cancer treatment target
2. Scientists advance field of research with publication of newly validated method for analyzing flavanols in cocoa
3. Newly found protein helps cells build tissues
4. Newly discovered foot points to a new kid on the hominin block
5. Scripps Research discoveries lead to newly approved drug for infant respiratory distress syndrome
6. Newly released FDA draft guidelines for biosimilar drugs to be discussed at conference
7. UF research on newly formed plants could lead to improved crop fertility
8. The H1N1 flu vaccine protects both pregnant women and newly-borns
9. Newly identified DNA repair defect linked to increased risk of leukemia relapse
10. Newly identified antibodies may improve pneumonia vaccine design
11. Newly discovered cell mechanism uses amplified nitric oxide to fight C. diff
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/17/2014)... Dec. 15, 2014 The Defense Logistics ... easier to detect and prevent counterfeit microcircuits from ... the agency started performing an in-house microcircuit anti-counterfeit ... the authenticity of purchased microcircuits while increasing their ... control measures will be conducted at DLA,s Electronics ...
(Date:12/17/2014)... 16, 2014 Research and Markets ... the "Global Chemical Sensor Market 2015-2019" ... http://photos.prnewswire.com/prnh/20130307/600769 One major trend ... for medical sensors in biomedical applications. Chemical sensors ... and correct diagnosis during surgical procedures. The Global ...
(Date:12/11/2014)... Research and Markets , ... http://www.researchandmarkets.com/research/twhjll/biometrics_market ) has announced the addition of the ...  report to their offering. One ... in technology. With continuous advances in technology, it ... latest standard that meets the needs and expectations ...
Breaking Biology News(10 mins):Defense Logistics Agency Launches DNA Marking Capability to Strengthen Microcircuit Supply Chain 2Defense Logistics Agency Launches DNA Marking Capability to Strengthen Microcircuit Supply Chain 3Global Chemical Sensor Market 2015-2019: Key Vendors are Abbott Laboratories, Bayer, Hoffmann La-Roche, Johnson & Johnson, NGK Spark Plugs and Robert Bosch 2Biometrics Market in the APAC Region 2015-2019: Key Vendors are 3M Cogent, NEC, Safran and Suprema 2
... women may worry about the effects of air pollution on ... carbon monoxide and fine particles in the air during pregnancy ... or preeclampsia -- a serious condition that arises only during ... a University at Buffalo epidemiologist. , The research was ...
... Safran, a professor at the Weizmann Institute in Israel, has ... Pierre-Gilles De Gennes Lecture Prize. The prize, accompanied by 1,000, ... (EPJE). Safran is the author of numerous articles in ... Prize, which was named after the Nobel laureate who founded ...
... cessation therapy is quickly taking shape. New evidence ... on Drug Abuse (NIDA) suggests that combining information about ... habits can accurately predict which nicotine replacement therapy will ... conceivable we,ll have a practical test that could take ...
Cached Biology News:Air pollution doesn't increase risk of preeclampsia, early delivery, study finds 2Personalized approach to smoking cessation may be reality in 3-5 years 2Personalized approach to smoking cessation may be reality in 3-5 years 3
(Date:12/24/2014)... San Diego, CA (PRWEB) December 23, 2014 ... Contest where their Twitter followers can submit their ... for themselves and their lab mates. , For those ... beloved lab mates, the Pipette.com Holiday in the Lab ... encourages Pipette.com Twitter followers to send pictures ...
(Date:12/24/2014)... -- Rock Creek Pharmaceuticals, Inc., (NASDAQ: RCPI ) ... Application (CTA) with the United Kingdom,s ... approval to initiate clinical trials for the continued development ... on the Company receiving CTA regulatory approval, the Company ... the safety, tolerability and dose escalation of Anatabine Citrate ...
(Date:12/22/2014)... , Dec. 22, 2014  Alternative Energy & ... it has signed a letter of intent to ... developed and patented a nanotechnology-based development platform used ... that enable rapid on-site collection and testing to ... health issues in an immediate, non-invasive and cost-effective ...
(Date:12/22/2014)... Fertility Associates of Memphis has announced ... , a network of more than 20 contributing ... have fast access to a national pool of frozen ... Fertility Associates of Memphis is the only fertility clinic ... , Dr. William Kutteh , director of Fertility ...
Breaking Biology Technology:Major Pipette Distributor Pipette.com Announces their Holiday in the Lab Contest 2Rock Creek Pharmaceuticals Files Clinical Trial Application in the UK for Clinical Trials of Anatabine Citrate Formulations 2Rock Creek Pharmaceuticals Files Clinical Trial Application in the UK for Clinical Trials of Anatabine Citrate Formulations 3ALNE Announces Intention To Acquire BioTechPharma 2Fertility Associates of Memphis Announces Partnership with Donor Egg Bank USA 2Fertility Associates of Memphis Announces Partnership with Donor Egg Bank USA 3
... plc (LSE: SHP, NASDAQ:, SHPGY ), the global specialty biopharmaceutical company, announces that at its,Annual General Meeting today, ... , , ... For* Against Withheld**, 1. ... together with the, ...
... BeaconEquity.com announces the availability of Stock Alerts on stocks making ... stocks are parading up the charts. So how does swine ... three stocks (BCRX, AVII, DVAX) reeling from influenza news that ... stockhideout.com .Today,s Stock Alerts include: ...
... US Oncology, Inc. will announce its financial results for the ... conference call and simultaneous webcast will be hosted by management ... Additional information will be available on the company,s Web site, ... the day of the earnings announcement. US/Canada Dial-in #: ...
Cached Biology Technology:Shire plc: Results of the Annual General Meeting Held on April 28, 2009 2Antiviral Drugmaker Shares Soar as Swine Flu Spreads; Beacon Equity Issues Stock Alerts on: HEB, GNBT, BCRX, DVAX, NVAX, SVA 2Antiviral Drugmaker Shares Soar as Swine Flu Spreads; Beacon Equity Issues Stock Alerts on: HEB, GNBT, BCRX, DVAX, NVAX, SVA 3US Oncology to Report 2009 First Quarter Operating Results 2
ImageQuant 100 UV, 1 EA. Category: ImageQuant CCD Imagers....
ImageQuant 300, 1 EA. Category: ImageQuant CCD Imagers....
Recombinant Feline IL-12/IL-23 p40...
RABBIT ANTI ISOCITRATE DEHYDROGENASE...
Biology Products: