Navigation Links
Newly described type of immune cell and T cells share similar path to maturity
Date:5/14/2013

C2, and were unable to mount an ILC2 immune response. Forced expression of TCF-1 in bone marrow progenitor cells in the mice partially bypassed the requirement for Notch signaling in the generation of ILC2 in the mice. The researchers suggest that transcription factors such as TCF-1 that underlie early steps of T cell development are also implicated in the development of innate lymphoid cells.

The collaborators' next steps are to better understand the basic steps of ILC development and build mouse models to test ILC function. "We want to know where ILCs develop in the body and what progenitor cells give rise to ILCs." says Bhandoola. "If we succeed in constructing mouse models missing different types of ILC, our collaborators can use them to better figure out what these cells do, and perhaps eventually how to control them."


'/>"/>

Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine
Source:Eurekalert

Page: 1 2

Related biology news :

1. FRAX newly released as version 3.8 -- Over 5 million online calculations since June 2011
2. Marriage can threaten health: Study finds satisfied newlyweds more likely to gain weight
3. Soils in newly forested areas store substantial carbon that could help offset climate change
4. Logging debris gives newly planted Douglas-fir forests a leg-up
5. Newly identified natural protein blocks HIV, other deadly viruses
6. Newly discovered plant structure may lead to improved biofuel processing
7. Newly discovered scarecrow gene might trigger big boost in food production
8. Newly discovered effects of vitamin D on cancer
9. Newly demonstrated capabilities of low-powered nanotweezers may benefit cellular-level studies
10. Newly discovered letters and translated German ode expand Texas link to infamous Bone Wars
11. ORNLs newly licensed neutron detector will advance human disease research
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/28/2014)... the bug hunter, but the target of his work ... identified with special methods and instruments. Benjamin Hause, an ... Laboratory at Kansas State University, recently published an article ... is an important find in the United States. , ... know what it was," Hause said. "We used next-generation ...
(Date:7/28/2014)... that can help advance the genetic engineering of ... has been developed by researchers with the U.S. ... a multi-institutional partnership led by Lawrence Berkeley National ... an assay that enables scientists to identify and ... components in the biosynthesis of plant cell walls. ...
(Date:7/28/2014)... for Biologically Inspired Engineering at Harvard University today ... commercialized by a newly formed private company to ... medicine products. The announcement follows a ... Development (OTD) and the start-up Emulate Inc., relating ... Organs-on-Chips platform. , "This is a big ...
Breaking Biology News(10 mins):Researcher using next-generation sequencing to rapidly identify pathogens 2Researcher using next-generation sequencing to rapidly identify pathogens 3How sweet it is 2How sweet it is 3Wyss Institute's technology translation engine launches 'Organs-on-Chips' company 2Wyss Institute's technology translation engine launches 'Organs-on-Chips' company 3
... pays to be rare—think of a one-of-a-kind diamond, a ... , Now, new research suggests that being rare has ... University of Toronto Mississauga who in the 1980s discovered ... fruit flies, has identified the benefit of rarity in ...
... the La Jolla Institute for Allergy & Immunology have ... be reduced ?and in some cases eliminated ?through the ... the immune system. The research team’s findings, based ... implications for other chronic virus infections, such as hepatitis ...
... how ocean circulation is working in the current that ... from underwater volcanoes. The details are published in Nature ... Garabato of the National Oceanography Centre, Southampton (formerly based ... 'short-circuit' in the circulation of the world's oceans that ...
Cached Biology News:Survival of the rarest: Fruit flies shed light on the evolution of behavior 2LIAI scientists make important finding on cytomegalovirus transmission 2'Short-circuit' found in ocean circulation 2
(Date:7/29/2014)... (PRWEB) July 29, 2014 EXpressLO LLC, ... lift out specimen preparation solutions, has been granted patent ... for specimen manipulation methods incorporating a unique specimen carrier ... This is the second company patent for EXpressLO LLC ... , These complementary patents extend EXpressLO’s portfolio ...
(Date:7/28/2014)... July 28, 2014 The Workgroup for ... on the use of health IT to create efficiencies ... Plan Identifier (HPID) Workgroup has developed an issue ... Plan and Payer?” The HPID Workgroup, a part of ... the Centers for Medicare and Medicaid Services (CMS) to ...
(Date:7/28/2014)... , July 28, 2014 Research ... "Global Synthetic Biology Market 2014-2018" report to ... The term synthetic biology covers the designing ... organisms as well as the redesigning of natural biological ... considered to be a form of extreme genetic engineering ...
(Date:7/28/2014)... Boston, MA (PRWEB) July 28, 2014 ... with two researchers to further develop potential treatments for ... brain tumor, in combination with their patented vaccine platform, ... and Duke University, are based on the work of ... of Neurosurgery at The Preston Robert Tisch Brain Tumor ...
Breaking Biology Technology:EXpressLO LLC Granted Second U.S. Patent for Innovative Specimen Preparation Methods 2WEDI’s HPID Workgroup Announces Release of Issue Brief: “What is the Difference Between a Health Plan and Payer?” 2Global Synthetic Biology Market 2014-2018 2String of Collaborations Launch Immunomic Therapeutics’ Brain Tumor Program Pipeline 2String of Collaborations Launch Immunomic Therapeutics’ Brain Tumor Program Pipeline 3String of Collaborations Launch Immunomic Therapeutics’ Brain Tumor Program Pipeline 4
... one of six states to receive a $50,000 grant ... network further into the Internet age. , ,Wisconsin's grant ... of Justice Assistance, which houses the Wisconsin Justice ... maintaining, promoting and coordinating automated justice information systems. , ...
... the learning acquired in the program but rather the blue-chip roster ... mythology goes, you can call on a fellow alum to help ... will be of value once again. , ,Though I can't say ... can attest to the power of alumni connections. , ,While I'm ...
... of health-care and business technology, announced a seven-year contract with ... Information System (MMIS). The new system is expected to be ... contracts EDS to implement its InterChange health system on the ... Services . The contract is worth approximately $189 million and ...
Cached Biology Technology:State receives grant for justice information sharing 2Pay attention to your alumni connections when job hunting 2Pay attention to your alumni connections when job hunting 3Pay attention to your alumni connections when job hunting 4State picks long-time vendor for $189m Medicaid information system 2
... (GST) is commonly used as a fusion ... (1). The GSTTag sequence has been reported ... cases the solubility of its fusion partners. ... form, GSTTag fusion proteins can be purified ...
... applications for the use of small interfering ... via the RNA interference (RNAi) pathway have ... molecular biology fields. siRNA for experimental use ... or enzymatically, and then transfected into the ...
... unique collision reaction interface (CRI) system*, ... troublesome spectroscopic interferences. The result is ... the worry of complex multipole or ... And, by coupling autotuning of all ...
Acetylcholinesterase (human brain, AChE)...
Biology Products: