Navigation Links
Newly demonstrated capabilities of low-powered nanotweezers may benefit cellular-level studies
Date:9/17/2012

Using ultra-low input power densities, researchers at the University of Illinois at Urbana-Champaign have demonstrated for the first time how low-power "optical nanotweezers" can be used to trap, manipulate, and probe nanoparticles, including fragile biological samples.

"We already know that plasmonic nanoantennas enhance local fields by up to several orders of magnitude, and thus, previously showed that we can use these structures with a regular CW laser source to make very good optical tweezers," explains, Kimani Toussaint, Jr., assistant professor of mechanical science and engineering at Illinois. "This is exciting because, for the first time, we're showing that, the near-field optical forces can be enhanced even further, without doing anything extra in terms of fabrication, but rather simply by exploiting the high-peak powers associated with using a femtosecond (fs) optical source.

"We used an average power of 50 microwatts to trap, manipulate, and probe nanoparticles. This is 100x less power than what you would get from a standard laser pointer."

In their recent paper, "Femtosecond-pulsed plasmonic nanotweezers" published in the September 17 issue of Scientific Reports; doi:10.1038/srep00660), the researchers describe how a femtosecond-pulsed laser beam significantly augments the trapping strength of Au bowtie nanoantennas arrays (BNAs), and the first demonstration of use of femtosecond (fs) source for optical trapping with plasmonic nanotweezers.

"Our system operates at average power levels approximately three orders of magnitude lower than the expected optical damage threshold for biological structures, thereby making this technology very attractive for biological (lab-on-a-chip) applications such as cell manipulation," Toussaint added. "This system offers increased local diagnostic capabilities by permitting the probing of the nonlinear optical response of trapped specimens, enabling studies of in vitro fluorescent-tagged cells, or viruses using a single line for trapping and probing rather than two or more laser lines."

"We present strong evidence that a fs source could actually augment the near-field optical forces produced by the BNAs, and most likely, other nanoantenna systems, as well. To our knowledge, this has never been demonstrated," said Brian Roxworthy, a graduate student in Toussaint's PROBE (Photonics Research of Bio/nano Environments) lab group and first author of the paper. According to Roxworthy, the demonstration of controlled particle fusing could be important for creating novel nanostructures, as well as for enhancing the local magnetic field response, which will be important for the field of magnetic plasmonics.

The paper also demonstrated enhancement of trap stiffness of up to 2x that of a comparable continuous-wave (CW) nanotweezers and 5x that of conventional optical tweezers that employ a fs source; successful trapping and tweezing of spherical particles ranging from 80-nm to 1.2-um in diameter, metal, dielectric, and both fluorescent and non- fluorescent particles; enhancement of two-photon fluorescent signal from trapped microparticles in comparison to the response without the presence of the BNAs; enhancement of the second-harmonic signal of ~3.5x for the combined nanoparticle-BNA system compared to the bare BNAs; and fusing of Ag nanoparticles to the BNAS.


'/>"/>

Contact: Kimani C. Toussaint, Jr.
ktoussai@illinois.edu
217-244-4088
University of Illinois College of Engineering
Source:Eurekalert  

Related biology news :

1. Newly released FDA draft guidelines for biosimilar drugs to be discussed at conference
2. Scripps Research discoveries lead to newly approved drug for infant respiratory distress syndrome
3. Newly discovered foot points to a new kid on the hominin block
4. Newly found protein helps cells build tissues
5. Scientists advance field of research with publication of newly validated method for analyzing flavanols in cocoa
6. Key proteins newly discovered form and function may provide novel cancer treatment target
7. Newly discovered breast milk antibodies help neutralize HIV
8. Newly discovered dinosaur implies greater prevalence of feathers
9. U of M researchers: Newly discovered genetic markers could signal colon cancer development
10. ORNLs newly licensed neutron detector will advance human disease research
11. Newly discovered letters and translated German ode expand Texas link to infamous Bone Wars
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Newly demonstrated capabilities of low-powered nanotweezers may benefit cellular-level studies
(Date:1/4/2017)... VEGAS , Jan. 4, 2017  CES ... performance biometric sensor technology, today announced the launch ... sensor systems, the highly-accurate biometric sensor modules ... biometric technology, experience and expertise. The two ... Benchmark designed specifically for hearables, and Benchmark BW2.0, ...
(Date:12/20/2016)... , Dec. 20, 2016 The ... sharing, rental and leasing is stoking significant interest ... radio frequency technology, Bluetooth low energy (BLE), biometrics ... as the next wave of wireless technologies in ... access system to advanced access systems opens the ...
(Date:12/16/2016)... 2016 Research and Markets has announced the ... Forecast to 2021" report to their offering. ... The biometric vehicle access system ... CAGR of 14.06% from 2016 to 2021. The market is estimated ... reach 854.8 Million by 2021. The growth of the biometric vehicle ...
Breaking Biology News(10 mins):
(Date:1/12/2017)... ... January 12, 2017 , ... ... Vertebral Technologies, Inc., announces the successful outcome of the first lumbar fusion ... VTI (Vertebral Technologies, Inc.) has partnered with Mexico-based medical product company BioMedical ...
(Date:1/12/2017)... ... January 12, 2017 , ... After her brain cancer ... gave her only a few months to live. Now a paper publishing January ... Rosendahl’s disease and increased both the quantity and quality of her life: Adding ...
(Date:1/12/2017)... , January 12, 2017 The report "Direct-Fed Microbials Market by ... Form (Dry and Liquid), and Region - Global Forecast to 2022", published by ... in 2016 and projected to reach USD 1,399.6 Million by 2022, at a ... ... MarketsandMarkets Logo ...
(Date:1/11/2017)... Worcester, Mass. (PRWEB) , ... January 11, 2017 ... ... months in rural and urban clinics in Peru studying the pathogens that cause ... set her on a career path of discovery. , Now, as an assistant ...
Breaking Biology Technology: