Navigation Links
Newborn vitamin A reduces infant mortality
Date:7/6/2008

A single, oral dose of vitamin A, given to infants shortly after birth in the developing world can reduce their risk of death by 15 percent, according to a study conducted by researchers at the Johns Hopkins Bloomberg School of Public Health. The study is published in the July 2008 edition of the journal Pediatrics.

"It has long been known that vitamin A supplementation can reduce mortality in children over 6 months of age. Our study showed that vitamin A given at birth can also improve infant survival within the first 6 months of life," said Rolf D.W. Klemm, DrPH, MPH, the study's lead author and a researcher with the Bloomberg School's Center for Human Nutrition.

The study enrolled 15,937 newborns from rural communities in northwest Bangladesh, where over 90 percent of babies are born at home. Half were randomly selected to receive a 50,000 IU dose of vitamin A, while the other half received a placebo. A 200,000 IU dose of vitamin A is recommended semi-annually for older children. The vitamin A was given orally to the infants within a few days of birth, usually by 7 hours after delivery. The mortality rate for the vitamin A group was 38.5 deaths per 1,000 births compared to 45.1 deaths per 1,000 births for the non-vitamin A group.

Although vitamin A reduced infant deaths from all causes, lives were likely saved by reducing the severity of potentially fatal infections which are responsible for most deaths in early infancy in South Asia.

"This study supports the findings of previous vitamin A studies in Southern Asia where the evidence is now strong that vitamin A given to newborns can dramatically reduce mortality," said study co-author Keith West, DrPH, MPH, RD, the George G. Graham Professor in Infant and Child Nutrition at the Bloomberg School of Public Health. "More studies are urgently needed to determine if newborn vitamin A supplementation would reduce mortality among infants in other regions, especially Africa."

"We are excited by the results of this study, that build on two previous studies in South Asia, confirming this low cost intervention can significantly contribute to reducing mortality in the first 6 months of life," said Kent R. Hill, assistant administrator for Global Health at the U.S. Agency for International Development (USAID). He added, "A key next step is to consider the operational issues for using this intervention." In conjunction with other partners, USAID is conducting operations research in Nepal and Bangladesh to determine possible approaches for delivering vitamin A to newborn infants.

In the 1980s, Alfred Sommer, MD, MHS, demonstrated that vitamin A deficiency dramatically increased the risk of child mortality. Sommer, along with West and colleagues from Hopkins further demonstrated that a single dose of vitamin A could reduce child mortality by 34 percent. The control of vitamin A deficiency is a global goal of the World Health Organization and is considered one of the most cost-effective of all health interventions for saving young lives.

"Because childhood mortality is greatest during the first few months of life, a single dose of vitamin A administered by mouth to a newborn child can save the lives of an additional 300,000 children in Asia every year," said Alfred Sommer, MD, MHS, professor and dean emeritus of the Bloomberg School of Public Health. "That is on top of the one million lives a year that would be saved by dosing all vitamin A deficient children twice a year from six months through 5 years of age."


'/>"/>

Contact: Tim Parsons
tmparson@jhsph.edu
410-955-7619
Johns Hopkins University Bloomberg School of Public Health
Source:Eurekalert

Related biology news :

1. MIT: Prenatal arsenic exposure detected in newborns
2. New technology may prevent vitamin B12 deficient seniors and vegetarians from needing injections
3. Vitamin D: New way to treat heart failure?
4. Moores UCSD Cancer Center study links vitamin D, type 1 diabetes
5. Study identifies trends of vitamin B6 status in US population sample
6. Vitamin D in brain function
7. Vitamin D and calcium influence cell death in the colon, researchers find
8. Vitamin E may increase tuberculosis risk in male smokers with high vitamin C intake
9. Team finds an economical way to boost the vitamin A content of maize
10. New way to produce high-vitamin corn could improve nutrition in developing countries
11. Jefferson scientists studying the effects of high-dose vitamin C on non-Hodgkin lymphoma patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/14/2017)... IBM ) is introducing several innovative partner startups at VivaTech ... startups and global businesses, taking place in Paris ... will showcase the solutions they have built with IBM Watson ... France is one of the most dynamic ... in the number of startups created between 2012 and 2015*, ...
(Date:5/6/2017)... , May 5, 2017 ... just announced a new breakthrough in biometric authentication ... exploits quantum mechanical properties to perform biometric authentication. These ... smart semiconductor material created by Ram Group and ... finance, entertainment, transportation, supply chains and security. Ram ...
(Date:4/17/2017)... NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" or the ... Annual Report on Form 10-K on Thursday April 13, 2017 with ... ... Relations section of the Company,s website at http://www.nxt-id.com  under "SEC ... . 2016 Year Highlights: Acquisition ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... October 12, 2017 , ... ... launched Rosalind™, the first-ever genomics analysis platform specifically designed for life science ... in honor of pioneering researcher Rosalind Franklin, who made a major contribution ...
(Date:10/11/2017)... ... October 11, 2017 , ... Proscia Inc ., ... a Webinar titled, “Pathology is going digital. Is your lab ready?” with Dr. ... best practices and how Proscia improves lab economics and realizes an increase in ...
(Date:10/11/2017)... ... October 11, 2017 , ... Singh ... orphan drug designation to SBT-100, its novel anti-STAT3 (Signal Transducer and Activator of ... SBT-100 is able to cross the cell membrane and bind intracellular STAT3 and ...
(Date:10/10/2017)... International research firm Parks Associates announced today that ... TMA 2017 Annual Meeting , October 11 in Scottsdale, ... security market and how smart safety and security products impact the competitive ... Parks Associates: Smart Home Devices: Main ... "The residential security market has experienced continued ...
Breaking Biology Technology: