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Newborn screening increases survival outcome for patients with severe combined immunodeficiency
Date:1/27/2011

(WASHINGTON, January 27, 2011) Severe Combined Immunodeficiency (SCID) occurs in just one out of every 50,000 to 100,000 births in the United States, yet it is the most serious primary immunodeficiency disorder.[1] A study published today in Blood, the Journal of the American Society of Hematology (ASH), demonstrates that babies with SCID who are diagnosed at birth and receive a hematopoietic stem cell transplant (HSCT), which is the transplantation of blood-forming stem cells, have significantly improved survival.

SCID is a rare group of genetic disorders characterized by severe abnormalities of the development and function of the immune system due to a defect in the specialized white blood cells that defend the body from infection. Patients with SCID lack almost all immune defenses, are prone to serious, life-threatening infections within the first few months of life, and require major treatment for survival beyond infancy. The most effective treatment for SCID is HSCT from the bone marrow of a healthy person. According to the Immune Deficiency Foundation, if a baby with SCID receives a bone marrow transplant in the first 3.5 months of life, the survival rate can be as high as 94 percent.[2]

"If diagnosed early enough, it is probable th
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Contact: Lindsey Love
webmaster@hematology.org
202-552-4925
American Society of Hematology
Source:Eurekalert

Page: 1 2 3

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