Navigation Links
New year, new vitamin C discovery: It 'cures' mice with accelerated aging disease
Date:1/4/2010

A new research discovery published in the January 2010 print issue of the FASEB Journal (http://www.fasebj.org) suggests that treatments for disorders that cause accelerated aging, particularly Werner's syndrome, might come straight from the family medicine chest. In the research report, a team of Canadian scientists show that vitamin C stops and even reverses accelerated aging in a mouse model of Werner's syndrome, but the discovery may also be applicable to other progeroid syndromes. People with Werner's syndrome begin to show signs of accelerated aging in their 20s and develop age-related diseases and generally die before the age of 50.

"Our study clearly indicates that a healthy organism or individuals with no health problems do not require a large amount of vitamin C in order to increase their lifespan, especially if they have a balanced diet and they exercise," said Michel Lebel, Ph.D., co-author of the study from the Centre de Recherche en Cancerologie in Quebec, Canada. "An organism or individual with a mutation in the WRN gene or any gene affected by the WRN protein, and thus predisposes them to several age-related diseases, may benefit from a diet with the appropriate amount of vitamin C."

Scientists treated both normal mice and mice with a mutation in the gene responsible for Werner's syndrome (WRN gene) with vitamin C in drinking water. Before treatment, the mice with a mutated WRN gene were fat, diabetic, and developing heart disease and cancer. After treatment, the mutant mice were as healthy as the normal mice and lived a normal lifespan. Vitamin C also improved how the mice stored and burned fat, decreased tissue inflammation and decreased oxidative stress in the WRN mice. The healthy mice did not appear to benefit from vitamin C.

"Vitamin C has become one of the most misunderstood substances in our medicine cabinets and food," said Gerald Weissmann, M.D., Editor-in-Chief of
'/>"/>

Contact: Cody Mooneyhan
cmooneyhan@faseb.org
301-634-7104
Federation of American Societies for Experimental Biology
Source:Eurekalert

Page: 1 2

Related biology news :

1. Putting limits on vitamin E
2. Multiple health concerns surface as winter, vitamin D deficiences arrive
3. Women at risk from vitamin A deficiency
4. New study links vitamin D deficiency to cardiovascular disease and death
5. Latest analysis confirms suboptimal vitamin D levels in millions of US children
6. Too much of a good thing? Scientists explain cellular effects of vitamin A overdose and deficiency
7. Oxidized form of a common vitamin may bring relief for ulcerative colitis
8. Insufficient levels of vitamin D puts elderly at increased risk of dying from heart disease
9. Can an over-the-counter vitamin-like substance slow the progression of Parkinsons disease?
10. Vitamin C deficiency impairs early brain development
11. Is vitamin D deficiency linked to Alzheimers disease and vascular dementia?
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2014)... a novel method to help kidney stone sufferers ... treatment possible., Kidney stones represent a major medical ... left untreated, apart from being particularly painful, they ... In many patients treated successfully, stone recurrence is ... approach to diagnosis and treatment needs to be ...
(Date:4/17/2014)... the Cell Press journal Current Biology on ... novel sex lives. The Brazilian insects, which represent four ... , are the first example of an animal with ... identified in several different animals, Neotrogla is ... also reversed," says Kazunori Yoshizawa from Hokkaido University in ...
(Date:4/17/2014)... Branch at Galveston are the first to recommend ... cancer should begin colorectal cancer screening earlier than ... a high incidence of secondary colorectal cancers among ... recommendations that the younger women in this group ... their initial cervical cancer diagnosis instead of waiting ...
Breaking Biology News(10 mins):In sex-reversed cave insects, females have the penises 2Radiation therapy for cervical cancer increases risk for colorectal cancer 2
... University of Geneva have discovered a genetic mechanism that defines ... only a secondary role. The research published in Cell ... found in a DNA sequence that was thought, incorrectly, to ... when combined with one another, modulate the activity of the ...
... Urban legend warns shoveling snow causes heart attacks, and the ... with a family history of premature cardiovascular disease. However, until ... Two of the most important cardiology associations in the ... risk physical activity, but all the citation references indicate that ...
... end rot on tomatoes and cucumbers, bitter-pit in apples ... only compromises the flavor but also causes significant harvest ... be traced back to insufficient calcium uptake or faulty ... occur even if the soil provides sufficient calcium. A ...
Cached Biology News:Finger (mal)formation reveals surprise function of desert DNA 2
(Date:1/15/2014)... (PRWEB) January 15, 2014 DTS Language ... its Online Web Portal for Life Science organizations who need ... specify the subject matter of their documents in advance with ... help reduce time-to-delivery of translations, often a critical factor in ...
(Date:1/15/2014)... 15, 2014 TaiGen Biotechnology Company, Limited ("TaiGen") today ... R-Pharm, a leading Russian pharmaceutical company, to develop and ... Russian Federation , Turkey ... is a novel antibiotic for the treatment of bacterial ...
(Date:1/14/2014)... , Jan. 14, 2014  3D Communications, a leading provider of strategic ... business, and media events in the United States ... associate Virginia Cox , JD, is returning to the firm,s ... Cox re-joins 3D after more than two years of service ...
(Date:1/14/2014)... BETHESDA, Md. , Jan. 14, 2014  Organovo announced ... from the National Institutes of Health (NIH) to help ... effective treatments to patients on a faster timeline. Organovo ... Sciences (NCATS) and the National Eye Institute (NEI) to ...
Breaking Biology Technology:DTS Improves Efficiency for Life Science Document Translations 2TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 2TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 3TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 4Former FDA Associate Commissioner Returns To 3D Communications 2Organovo Announces Collaboration with National Institutes of Health 2Organovo Announces Collaboration with National Institutes of Health 3
... of,the 2007 Nobel Prize in Physiology or Medicine ... Americans for Medical,Progress congratulates Mario R. Capecchi, Martin ... by the Karolinska Institute for their,animal-based research that ... treatments and cures for countless serious ailments., ...
... Company to Present Unique Business Model, SAN ... health,and wellness company and recent consecutive year award ... genetic research,announces today that it has been selected ... investor meeting, October 17, 2007 in San,Francisco, CA. ...
... 9 Boston Scientific,Corporation (NYSE: BSX ) ... cardioverter defibrillator (ICD). This approval,represents the first Boston ... death (SCD). The CONFIENT ICD, with an ... unnecessary right ventricular pacing. This product also,contains wireless ...
Cached Biology Technology:Nobel Award in Medicine Holds Strong Messsage for Animal Activists 2Salugen to Present at Nutrition Capital Network's First In-Person Investor Meeting 2Boston Scientific Announces European Approval of Next-Generation Implantable Defibrillator 2Boston Scientific Announces European Approval of Next-Generation Implantable Defibrillator 3
Monocarboxylate (lactate) transporter 2...
Chicken Anti-Human Stomatin-like 2 (STOML2 Polyclonal AntibodyNew Applications: ELISA, Western Blot...
MagSi monodispers, magnetic silica particles with modified surface for SO3 coupling chemistry....
Anti-Chicken IgY, (IgG) F(ab')2 Fragment Specific....
Biology Products: