Navigation Links
New ways to disarm deadly South American hemorrhagic fever viruses
Date:3/8/2010

This release is available in Spanish.

New World hemorrhagic fevers are emerging infectious diseases found in South America that can cause terrible, Ebola-like symptoms. Current treatments are expensive and only partially effective.

Now, Howard Hughes Medical Institute (HHMI) researchers have discovered exactly how one type of New World hemorrhagic fever virus latches onto and infects human cells, offering a much-needed lead toward new treatments.

"New World hemorrhagic fevers are nasty, serious, and often fatal diseases," says Stephen C. Harrison, an HHMI investigator at Harvard Medical School and senior author of the report, published March 7, 2010, in Nature Structural & Molecular Biology. "The need for new interventions is high."

Arenaviruses, the infectious agents that cause New World hemorrhagic fevers, circulate naturally in rodents and can infect people who are in close contact with the animals. Symptoms include severe inflammation and bleeding from the mouth, nose, eyes, and other orifices. Most outbreaks occur in rural regions of Bolivia, Venezuela, Argentina, and Brazil. "The outbreaks of New World hemorrhagic fever tend to be brief and brutal, with mortality rates of 20 to 30 percent," says Jonathan Abraham, an M.D./Ph.D. candidate at Harvard University and first author of the paper. "These viruses aren't a huge public health issue yet, but you could say the New World hemorrhagic fevers are an emerging disease threat."

Researchers have known about these viruses since the 1960s, but the molecular basis of the disease has only been tackled recently, says Abraham, whose graduate studies are funded by HHMI through a Gilliam Fellowship for Advanced Study. The Gilliam Fellowships program currently supports the doctoral education of 30 exceptional students from disadvantaged backgrounds.

In 2007, Abraham
'/>"/>

Contact: Andrea Widener
widenera@hhmi.org
301-215-8807
Howard Hughes Medical Institute
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Scientists ramp up ability of poplar plants to disarm toxic pollutants
2. Ebola virus disarmed by excising a single gene
3. Disarming specialized stem cells might combat deadly ovarian cancer
4. Scripps research team blocks bacterial communication system to prevent deadly staph infections
5. Northwestern to expose most deadly infectious diseases in 3-D
6. Best treatment identified to reduce deadly Staph infections
7. Research unveils new hope for deadly childhood disease
8. Deadly genetic disease prevented before birth in zebrafish
9. Ayurvedic nightshade deadly for dengue mosquito
10. Sydney harbors deadly diet for sea creatures
11. New vaccine may give long-term defense against deadly bird flu and its variant forms
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... with other group members to reduce aggression and gain ... strategy for grooming activities shows a certain pattern across ... scientific journal Biology Letters . , Grooming between ... without ulterior motives. To be groomed has hygienic benefits ... another individual can provide access to infants, mating opportunities ...
(Date:7/11/2014)... mesenchymal stem cells can stimulate neurogenesis in the brain ... (AD) and improve tissue and function injury under the ... the therapeutic effect of adipose-derived stem cells (ADSCs) transplantation ... oxidative injury and neurogenesis in the brain of AD ... Life Sciences, Tsinghua University, China transplanted ADSCs into the ...
(Date:7/11/2014)... to study the proteins that let nerve cells send ... stumbled upon a biological tactic that may offer a ... a safe and environmentally responsible way. , Their ... one species and harmless for a closely related onesuggests ... without harming beneficial species like bees. A summary of ...
Breaking Biology News(10 mins):Baboons groom early in the day to get benefits later 2Potent spider toxin 'electrocutes' German, not American, cockroaches 2Potent spider toxin 'electrocutes' German, not American, cockroaches 3
... of Health and Human Services (HHS) today announced the ... up research on the causes of common diseases such ... initiative boosts funding at the National Institutes of Health ... and environmental underpinnings of common illnesses. The other initiative ...
... may be no surprise that marine reserves protect the fish ... of Exeter have shown for the first time that they ... In a paper in the prestigious journal Science, Dr Peter ... the Bahamas was affected by the return of the reef's ...
... major players in the cruise industry, including cruise ... with civil society organizations - are taking proactive ... tourism while preserving cruise destinations, according to a ... Stewardship in Cruise Destinations issued by Conservation International's ...
Cached Biology News:Two NIH initiatives launch intensive efforts to find roots of common diseases 2Two NIH initiatives launch intensive efforts to find roots of common diseases 3Two NIH initiatives launch intensive efforts to find roots of common diseases 4Two NIH initiatives launch intensive efforts to find roots of common diseases 5Two NIH initiatives launch intensive efforts to find roots of common diseases 6Two NIH initiatives launch intensive efforts to find roots of common diseases 7Two NIH initiatives launch intensive efforts to find roots of common diseases 8How marine reserves are giving coral reefs a helping hand 2Report finds cruise industry is protecting the precious places it visits 2Report finds cruise industry is protecting the precious places it visits 3Report finds cruise industry is protecting the precious places it visits 4
(Date:7/10/2014)...  Kainos Capital, a firm specializing in acquiring and ... has acquired the Slim-Fast brand from Unilever. Unilever will ... the transaction were not disclosed. Slim-Fast is ... markets ready-to-drink shakes, powders, bars and snacks to retail ... in the United Kingdom and ...
(Date:7/10/2014)... Ceres, Inc . (Nasdaq: CERE ), an ... for the three months ended May 31, 2014 and ... reported that the company and its customers have made ... Brazil, which concluded in June, despite dry and hot ... part of the growing season. Yields of several of ...
(Date:7/10/2014)... Using microscopic polymer light resonators that expand ... MIT,s Quantum Photonics Laboratory have developed new optical ... range. Optical sensors are ideal for detecting trace ... compact, lightweight nature, and immunity to electromagnetic interference. ... developed before, the MIT team conceived an extremely ...
(Date:7/10/2014)... quantum Hall effect in bilayer graphene and shown that ... an electric field. , The fractional quantum Hall ... sheets are exposed to large magnetic fields, is a ... electrons behave as a single system. However, while the ... details of this collective behavior remain not well understood, ...
Breaking Biology Technology:Kainos Capital Acquires Slim-Fast From Unilever 2Ceres Announces Fiscal Third Quarter 2014 Financial Results 2Ceres Announces Fiscal Third Quarter 2014 Financial Results 3Ceres Announces Fiscal Third Quarter 2014 Financial Results 4Ceres Announces Fiscal Third Quarter 2014 Financial Results 5Ceres Announces Fiscal Third Quarter 2014 Financial Results 6Ceres Announces Fiscal Third Quarter 2014 Financial Results 7Ceres Announces Fiscal Third Quarter 2014 Financial Results 8Ceres Announces Fiscal Third Quarter 2014 Financial Results 9Swell new sensors 2Columbia researchers observe tunable quantum behavior in bilayer graphene 2Columbia researchers observe tunable quantum behavior in bilayer graphene 3
... Sept. 16 Genoptix, Inc.,(Nasdaq: GXDX ), a ... the UBS Global Life Sciences Conference,scheduled to take place ... September 22,- 25, 2008., Douglas Schuling, Senior Vice ... on Monday, September 22, beginning at,approximately 3:30 pm EDT. ...
... answer to ensuring a safe supply of drinking water ... or where water contamination is rife. Writing in the ... India explain how carbon nanotubes could replace conventional materials ... access to safe drinking water will continue to grow ...
... Symmetry Medical Inc.,(NYSE: SMA ), a leading ... and other medical markets, announced today that,Brian S. Moore, ... the UBS Global Life Sciences Conference at The Grand ... 25, 2008 at 11:30 a.m. ET., A live ...
Cached Biology Technology:Genoptix Announces Participation at the UBS Global Life Sciences Conference 2Water purification down the nanotubes 2Symmetry Medical to Present at UBS Global Life Sciences Conference 2
prototype Nco I...
... is aseptically collected via cardiac puncture from 3 ... mixed sex). It is then centrifuged and frozen ... filtered and bottled at 4C then stored at ... HAVE ALWAYS USED PEL-FREEZ COMPLEMENT, YOU CAN NOW ...
These disposable button tethers are designed for rat infusion studies lasting more than 2 weeks. After one to two weeks the subcutaneous tissue will grow into the Dacron mesh, making the sutures irre...
Performance, mycoplasma, virus, and endotoxin tested...
Biology Products: