Navigation Links
New way to generate abundant functional blood vessel cells from human stem cells discovered
Date:1/20/2010

NEW YORK (Jan. 20, 2010) -- In a significant step toward restoring healthy blood circulation to treat a variety of diseases, a team of scientists at Weill Cornell Medical College has developed a new technique and described a novel mechanism for turning human embryonic and pluripotent stem cells into plentiful, functional endothelial cells, which are critical to the formation of blood vessels. Endothelial cells form the interior "lining" of all blood vessels and are the main component of capillaries, the smallest and most abundant vessels. In the near future, the researchers believe, it will be possible to inject these cells into humans to heal damaged organs and tissues.

The new approach allows scientists to generate virtually unlimited quantities of durable endothelial cells -- more than 40-fold the quantity possible with previous approaches. Based on insights into the genetic mechanisms that regulate how embryonic stem cells form vascular endothelial cells, the approach may also yield new ways to study genetically inherited vascular diseases. The study appears in the advance online issue of Nature Biotechnology.

"This technique is the first of its kind with serious potential as a treatment for a diverse array of diseases, especially cardiovascular disease, stroke and vascular complications of diabetes," says Dr. Shahin Rafii, the study's senior author. Dr. Rafii is the Arthur B. Belfer Professor in Genetic Medicine and co-director of the Ansary Stem Cell Institute at Weill Cornell Medical College, and an investigator of the Howard Hughes Medical Institute.

In recent years, enormous hopes have been pinned on stem cells as the source of future cures and treatments. Indeed, human embryonic stem cells have the potential to become any one of the more than 200 types of adult cells. However, the factors and pathways that govern their differentiation to abundant derivatives that could be used to repair organs have remained poorly un
'/>"/>

Contact: Andrew Klein
ank2017@med.cornell.edu
212-821-0560
New York- Presbyterian Hospital/Weill Cornell Medical Center/Weill Cornell Medical College
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. Ethanol-powered vehicles generate more ozone than gas-powered ones
2. Supportive materials will help regenerate heart tissue
3. $2.4 million stimulus fuels effort to regenerate injured spinal cords
4. Stem cell success points to way to regenerate parathyroid glands
5. P[acman]-generated fruit fly gene library: A new research tool
6. Gene therapy appears safe to regenerate gum tissue
7. Cellulosic biofuel technology will generate low-cost green fuel, says major study
8. Researchers generate functional neurons from somatic cells
9. Columbia University scientist devises new way to more rapidly generate bone tissue
10. Fires regenerate African grassland
11. Cow power could generate electricity for millions
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... de Janeiro, Brazil- In the brains of all ... that allows an electric or chemical signal to ... Chemical synapses, which are the most abundant type ... Synapse formation is crucial for learning, memory, perception ... inhibitory synapses critical for brain function. For ...
(Date:7/10/2014)... June 27, 2014  The American Academy of ... of Standards and Technology (NIST) and the Department ... research and forensic science expert members to the ... an element of the NIST,s Organization of Scientific ... the first appointments made to the new FSSB ...
(Date:7/10/2014)... Mass. , June 30, 2014  Aware, Inc. ... biometrics software and services, previously announced on June 26, ... special cash dividend of $1.75 per share, or approximately ... date of July 10, 2014 and a payment date ... by NASDAQ that it had set an ex-dividend date ...
Breaking Biology News(10 mins):Blame it on the astrocytes 2Ten Members of the American Academy of Forensic Sciences Appointed to Forensic Science Standards Board (FSSB) 2Ten Members of the American Academy of Forensic Sciences Appointed to Forensic Science Standards Board (FSSB) 3NASDAQ Sets Ex-Dividend Date for Aware, Inc.'s Special Cash Dividend of $1.75 Per Share 2
... Ore. November 6, 2008. Although the Northwest Forest Plan ... land, forests in the driest regions are now at ... logging. A team of federal and university scientists recently ... discovered that elevated fire levels in the Pacific Northwest ...
... fungus has been found to produce a variety of ... known as Gliocladium roseum (NRRL 50073), lives ... Gary Strobel of Montana State University has found ... the particular diesel components produced can be varied by ...
... Turtles nesting along the Mississippi River and other areas ... temperatures, says a researcher from Iowa State University. ... biology, has studied turtle nesting habits and also accumulated ... habits of the turtles to find out when they ...
Cached Biology News:Wildfires result in loss of forests reserved by Northwest Forest Plan 2Obscure fungus produces diesel fuel components 2Turtles alter nesting dates due to temperature change says ISU researcher 2
(Date:7/10/2014)... Understanding the need for better quality and higher ... that currently exists in this area, ChanTest has recently ... validated ion channel and GPCR cell lines. ChanTest’s ... channels control many critical physiological functions throughout the body. ... to treat a variety of human diseases. , ...
(Date:7/10/2014)... (PRWEB) July 10, 2014 Robert Harman, DVM, ... Medicine company, is proud to announce the relaunch of his ... with a new series called “ What are Stem Cells ... an honest and straightforward foundation in the basics of stem ... decision on the right type of treatment when considering regenerative ...
(Date:7/10/2014)... CA (PRWEB) July 10, 2014 Senior ... institutions and professional associations, addressed the challenges of “Reducing ... Medical Device Industries” through strategic sourcing. Describing the partnership ... with the Supply Chain Management Institute ( SCMI) ... event on June 24 at the Kroc Institute of ...
(Date:7/10/2014)... July 10, 2014  Kainos Capital, a firm specializing ... announced that it has acquired the Slim-Fast brand from ... business. Terms of the transaction were not disclosed. ... replacement business that markets ready-to-drink shakes, powders, bars and ... and in the United Kingdom ...
Breaking Biology Technology:Leader in Ion Channel Research Announces Newly Validated and Re-Engineered Cells 2Leader in Ion Channel Research Announces Newly Validated and Re-Engineered Cells 3Robert Harman, DVM Talks About What Stem Cells are in His Latest Blog Series for Vet-Stem, Inc. 2Robert Harman, DVM Talks About What Stem Cells are in His Latest Blog Series for Vet-Stem, Inc. 3Biotech & Biopharm Supply Chain Management Executives Launch BSMA in San Diego 2Biotech & Biopharm Supply Chain Management Executives Launch BSMA in San Diego 3Biotech & Biopharm Supply Chain Management Executives Launch BSMA in San Diego 4Kainos Capital Acquires Slim-Fast From Unilever 2
... Cancer Prevention (CCP) began in 2007 with the single goal ... cancer.  It has now grown to a more than 6 ... media platform, Causes.com. Nearly five years later, CCP is an ... Medical School flagship teaching hospital, with all campaign funds channeled ...
... the launch of Curve™ Image Guided Surgery. Curve, the ... unveiling at the Congress of Neurological Surgeons (CNS) Annual ... based on years of feedback from our customers. Incorporating ... and has helped to produce the ultimate surgical navigation ...
... Oct. 1, 2011 This information is being released by ... in the second hepatitis C trial in Nevada, was called ... During questioning by the defense, Dr. Reingold testified transference of ... lack of hand washing, ungloved hands, bite blocks, biopsy equipment, ...
Cached Biology Technology:Campaign for Cancer Prevention Connects 6 Million+ Members on Facebook Causes to Groundbreaking Research at Brigham and Women's Hospital 2Campaign for Cancer Prevention Connects 6 Million+ Members on Facebook Causes to Groundbreaking Research at Brigham and Women's Hospital 3Campaign for Cancer Prevention Connects 6 Million+ Members on Facebook Causes to Groundbreaking Research at Brigham and Women's Hospital 4Brainlab Launches Newest Innovation in Image Guided Surgery Technology 2Brainlab Launches Newest Innovation in Image Guided Surgery Technology 3Defense Witness In Second Hepatitis C Trial In Nevada, Dr. Arthur Reingold, Testimony on Plausible Cause for Contamination Impeached 2
Human Cell Line Slides...
Mouse monoclonal [3576] to Yellow Fever Virus ( Abpromise for all tested applications). Antigen: Tissue / cell preparation...
... 2 Detection System combines the indirect ... principle and Signets unique formulation of ... and reliablility. Signet reagents will achieve ... and automated protocols. ,Signets USA ...
6X Loading Buffer is intended for gel electrophoresis of DNA fragments or PCR products....
Biology Products: