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New way to control disease-spreading mosquitoes: Make them hold their urine
Date:3/3/2010

ination. In lab experiments, Piermarini, Beyenbach and colleagues demonstrated that blocking the protein's function in the renal tubules with a drug reverses the enhanced rates of urination that would occur during blood feeding.

"Thus, blocking the function of this protein in natural populations of mosquitoes may limit their ability to survive the physiological stresses of a blood meal and to further transmit viruses," said Piermarini.

The Aedes aegypti renal system also serves as a valuable model for parts of the mammalian kidney, with similar cells in each system and possibly similar proteins, said the authors.


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Contact: Joe Schwartz
bjs54@cornell.edu
607-254-6235
Cornell University
Source:Eurekalert

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