Navigation Links
New virus discovered in patients with central nervous system infections
Date:6/17/2013

with suspected central nervous system infections or suspected viral encephalitis, the researchers generated 161,000 DNA sequence reads for further analysis.

Among these thousands of sequences, the researchers identified a sequence from a member of the Cyclovirus genus that was present in two patients, one adult and one child, both with acute central nervous system infections of unknown cause. Follow-up work with a technique called inverse PCR used that short sequence to determine the entire genome sequence of the virus present in one of the samples. CyCV-VN is a unique new species of Cyclovirus, a group that includes no known pathogens.

With the full genome in hand, the researchers went back to 642 samples from patients with suspected acute central nervous system infections and were able to detect the virus in samples from 26 patients (4 percent). The virus was not detected at all in samples from patients with non-infectious conditions of the central nervous system, like multiple sclerosis, a fact that argues that the virus could well be a human pathogen.

The virus was also detected in samples from farm animals in the province where the index patient lived: between 42 percent and 100 percent of fecal samples from pigs, ducks, and chickens in that region harbored viruses that are extremely closely related to CyCV-VN. This raises the possibility - but not certainty - say the authors, that livestock could represent a source for human infection with the virus.

Van also cautions that it is too soon to point an accusing finger at CyCV-VN. "Detection of a virus in human samples alone is insufficient to provide a direct link with an ongoing infection," he says. "Addressing the question of causation requires extensive effort."

Van says they are currently trying to isolate the virus in cell culture and develop a serological assay. If they are able to identify an antibody response to the virus in patient samples, h
'/>"/>

Contact: Jim Sliwa
jsliwa@asmusa.org
202-942-9297
American Society for Microbiology
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. New virus isolated from patients with severe brain infections
2. Saint Louis University researchers discover a way to detect new viruses
3. New Loyola study on hepatitis C virus entry factor
4. Alios BioPharma initiates Phase 1 clinical trial for respiratory syncytial virus infection
5. Evidence of host adaptation of avian-origin influenza A virus
6. Rotavirus vaccine developed in India demonstrates strong efficacy
7. Bird flu in live poultry markets are the source of viruses causing human infections
8. Source identification of H7N9 influenza virus causing human infections
9. University of Southern California scientists reveal natural process that blocks viruses
10. Predicting the next eye pathogen; analysis of a novel adenovirus
11. New mouse viruses could aid hepatitis research
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2015)... 31, 2015 NXT-ID, Inc. (NASDAQ: NXTD ) ... on the growing mobile commerce market and creator of ... provisional patent 62/198989 for ELECTRONIC CRYPTO-CURRENCY MANAGEMENT ... method to advance crypto-currencies such as Bitcoin into the ... uniform way to manage all payments.  ...
(Date:7/30/2015)... MOUNTAIN VIEW, Calif. , July 30, 2015 ... products and services for gene function analysis and ... CRISPR Guide RNA (sgRNA) Knockout Library targeting all ... to specifically and permanently "knock out" a gene,s ... library provides a high throughput screening tool so ...
(Date:7/27/2015)... , July 27, 2015   Zynx Health ... experience-based clinical improvement solutions, today announced that its ... now available on Android smartphones and tablets. With ... post-care organizations can use ZynxCarebook to securely exchange ... condition, streamline care transitions to other care settings, ...
Breaking Biology News(10 mins):NXT-ID Patents Electronic Crypto-Currency Management Technology 2NXT-ID Patents Electronic Crypto-Currency Management Technology 3NXT-ID Patents Electronic Crypto-Currency Management Technology 4CELLECTA, INC. Announces Launch of Human Whole Genome CRISPR Knockout Library 2Zynx Health Adds Android Device Support to ZynxCarebook Solution 2Zynx Health Adds Android Device Support to ZynxCarebook Solution 3
... historic meeting next week may decide the fate of tuna ... important marine resources. The Inter-American Tropical Tuna Commission ... 27 in Panama City, Panama, to reverse a trend ... of tuna stocks. Failure of the IATTC to compromise effectively ...
... in gaining major European Union funding to begin ... such as DNA, can be managed and made ... Centre for Integrated Genomic Medical Research (CIGMR), based ... a key role in developing the Biobanking and ...
... Worker Identification Credential (TWIC) Program, Ensures No ... MIAMI BEACH, Fla., June 17 ... high-performance solutions for trusted,credential assurance, reported that ... critical software to the Transportation Security Agency,s ...
Cached Biology News:Tuna populations at risk 2Manchester clears first hurdle in €170 million biobank building boom 2ID Solutions Awarded Full-Production Order for Fingerprint Processing Software for TWIC 2
(Date:7/29/2015)... , July 30, 2015 ... santé, publie ses résultats pour le premier semestre ... commente les résultats. Visionner l,interview vidéo ... http://www.eurobusinessmedia.com/ceo-direct/sanofi/sanofi-h1-2015-results-interview-with-ceo-olivier-brandicourt?utm_source=ceo-direct&utm_medium=wire Au sommaire de l,interview ... - Moteurs de croissance - Diabète ...
(Date:7/29/2015)... / Japan (Q2 2015: +14% CER / 20% of ... growth in China , as well as solid contributions from ... Europe / Middle East / ... gains in Germany , Turkey and ... / 49% of sales) grew 11%, excluding U.S. HPV sales, on demand across ...
(Date:7/29/2015)... 2015  AsureQuality and Ubiquitome have agreed to ... in food and primary production sectors. The collaboration ... device, the Freedom4. AsureQuality provides quality ... supermarket shelf for producers, processors and Competent Authorities ... disease control and pest management and surveillance programmes. ...
(Date:7/29/2015)... , ... July 29, 2015 , ... ... today announced its GHS Label Guide . To align chemical container labeling ... this guide includes explanations of label components, an example of an accurate label, ...
Breaking Biology Technology:QIAGEN Reports Results for Second Quarter and First Half of 2015 2QIAGEN Reports Results for Second Quarter and First Half of 2015 3QIAGEN Reports Results for Second Quarter and First Half of 2015 4QIAGEN Reports Results for Second Quarter and First Half of 2015 5QIAGEN Reports Results for Second Quarter and First Half of 2015 6QIAGEN Reports Results for Second Quarter and First Half of 2015 7QIAGEN Reports Results for Second Quarter and First Half of 2015 8QIAGEN Reports Results for Second Quarter and First Half of 2015 9QIAGEN Reports Results for Second Quarter and First Half of 2015 10AsureQuality and Ubiquitome Partner on Applications for Mobile Molecular Food Safety Testing 2Brady Announces a New GHS Label Guide 2
... SPEX ) reported that on July 21, 2008, ... the bid price of the,Company,s common stock for the ... minimum $1.00 per share required for continued listing,on NASDAQ. ... the Common Stock at,this time., Spherix has been ...
... July 23 Duska Therapeutics,Inc. (OTC Bulletin Board: ... comment a synopsis of a proposed Phase 3 ... U.S. Food and Drug Administration,s (the,"FDA") Division of ... communications with the FDA, including a face-to-face,meeting held ...
... July 23 NxStage Medical,Inc. (Nasdaq: NXTM ... announced ongoing public access to current summary,information derived ... (ESRD) who undergo hemodialysis at home on a ... the conventional regimen of therapy,received three times a ...
Cached Biology Technology:Spherix Receives NASDAQ Bid Price Deficiency Letter 2Duska Therapeutics Submits Phase 3 ATPace(TM) Protocol to FDA for Comment 2Duska Therapeutics Submits Phase 3 ATPace(TM) Protocol to FDA for Comment 3Duska Therapeutics Submits Phase 3 ATPace(TM) Protocol to FDA for Comment 4NxStage Announces Access to Demographic and Outcomes Information for the Growing U.S. Daily Home Hemodialysis Patient Population 2NxStage Announces Access to Demographic and Outcomes Information for the Growing U.S. Daily Home Hemodialysis Patient Population 3NxStage Announces Access to Demographic and Outcomes Information for the Growing U.S. Daily Home Hemodialysis Patient Population 4NxStage Announces Access to Demographic and Outcomes Information for the Growing U.S. Daily Home Hemodialysis Patient Population 5
... in Ham's F12K medium with 2 mM L-glutamine ... In order to keep the antigens in their ... cells are arrayed on a 12-well (5 mm) ... treated to enhance cellular attachment and to minimize ...
Mouse polyclonal antibody to REXO4 - XPMC2 prevents mitotic catastrophe 2 homolog (Xenopus laevis)...
... Stabilizer is an aqueous solution that contains ... chemicals in a PBS buffer (phosphate buffered ... product contains a combination of 0.02% methylisothiazolone ... StabilCoat Plus Stabilizer provides optimum performance for ...
... trays are disposable trays that ... that have been blotted onto ... eight 10.5 cm x 5 ... cut from blotted membrane and ...
Biology Products: