Navigation Links
New vaccine may give long-term defense against deadly bird flu and its variant forms
Date:4/17/2008

pathobiology. "How long it will last in humans, we don't know yet."

To produce the new vaccine, the scientists used a mutated common cold virus, known as an adenovirus, as a delivery system for important genes from two types of the H5N1 avian influenza. The adenovirus is incapable of multiplying and so cannot cause illness to people. By using the adenovirus vector technology, a couple of problems with existing vaccines used to fight annual flu outbreaks are solved.

Problems with current influenza vaccines include that they are made from eggs, a process that can take as long as six months. The vaccine Mittal and his research team has developed isn't grown in eggs, making vaccine production much faster.

Additionally it would be difficult under normal conditions to produce the hundreds of millions of doses needed to protect everyone at risk for highly pathogenic forms of bird flu. With the beginning of a pandemic, since H5N1 decimates poultry populations, the egg supply needed to produce vaccines would be drastically cut.

The new vaccine uses an adjuvant, molecules added to the vaccine that stimulate the body's immune system, so that lower doses of the vaccine can be used. The adjuvant also allows the vaccine to be stockpiled so more people can be vaccinated, and it helps the vaccine protect against variant forms of the H5N1. The only FDA-approved H5N1 vaccine protects against only that specific strain of flu and only works in about 60 percent of those immunized with a high dose.

"Adenoviral vector-based pandemic vaccines are an attractive option for developing countries where egg-independent cell-based vaccine technologies for other vaccines already are available," Sambhara said. "Since this process is already in place, our vaccine could be produced locally at an affordable price."

Since H5N1 has been known, it has changed so that there are now two main subgroups, called clades. Within one of the clades, five subcl
'/>"/>

Contact: Susan A. Steeves
ssteeves@purdue.edu
765-496-7481
Purdue University
Source:Eurekalert  

Page: 1 2 3 4

Related biology news :

1. Possible hepatitis C vaccine
2. Study by Pittsburgh researchers identifies possible vaccine target for chlamydia
3. New nanoparticle vaccine is more effective but less expensive
4. Flu vaccine in painless skin patches under development at Emory, Georgia Tech with NIH grants
5. Influenza vaccine causes weaker immune response for children of rural Gabon than in semi-urban areas
6. An Alzheimers vaccine?
7. Penn researchers find monkeys able to fend off AIDS-like symptoms with enhanced HIV vaccine
8. CWRU School of Medicine has evidence vaccine against malaria will reduce disease
9. HIV isolate from Kenya provides clues for vaccine design
10. Iowa State researchers look for smaller, cheaper, 1-dose vaccines
11. Vaccine for Ebola virus
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New vaccine may give long-term defense against deadly bird flu and its variant forms
(Date:7/24/2014)... Neiker-Tecnalia is currently conducting research into the potato genes ... characterised by a reduction in rainfall and increased extremes ... the most resistant genes in order to create new ... conditions.The research is also seeking to find out how ... of greater drought and higher and lower temperatures. , ...
(Date:7/24/2014)... in German . ... asthma sufferers worldwide, a further 600 million people living ... global population contending with allergic rhinitis (allergic inflammation of ... other organs and parts of the body beyond the ... the form of inflammatory bowel diseases such as colitis ...
(Date:7/24/2014)... release is available in German . ... to recognize and respond to threats to health, and ... detailed understanding of the mechanism underlying immunologic memory, however, ... have converged to support the hypothesis that the persistence ... cells with stem-cell-like potential. Until now, there was no ...
Breaking Biology News(10 mins):Neiker-Tecnalia is researching the potato genes that best adapt to climate change 2New drugs to combat asthma and the like 2New drugs to combat asthma and the like 3Experiments prove 'stemness' of individual immune memory cells 2Experiments prove 'stemness' of individual immune memory cells 3
... 2012 -- Over the past 30 years, numerous studies ... such as bipolar disorder, schizophrenia, anxiety disorder and dementia. ... causes behavior disorders in a range of mammals and ... patients, but study results have been inconsistent. Now, ...
... People who have Ulcerative Colitis (UC) or Ileal ... their time between flares is crucial to successfully living ... combination of drugs, dietary changes and, for many, the ... the dietary management of these conditions. Now, Sigma-Tau Pharmaceuticals, ...
... across the globe are trying to develop plans to ... footprint by reducing the associated greenhouse gas emissions. While ... more energy efficient lighting, windows, and building systems, deeper ... a rethinking of how future infrastructure and energy policies ...
Cached Biology News:Does Borna disease virus cause mental illness? 2Maker of VSL#3 probiotic offers assistance program for ulcerative colitis and ileal pouch patients 2Columbia engineers map energy use in NYC buildings 2Columbia engineers map energy use in NYC buildings 3
(Date:7/24/2014)... 2014  Asterias Biotherapeutics, Inc. (OTCBB: ASTYV), a ... regenerative medicine, announced today that it will host ... on Tuesday, July 29, 2014, at 4:30 p.m. ... an overview of Asterias, business strategy and product ... http://www.ustream.tv/channel/asterias-biotherapeutics at least 15 minutes before the ...
(Date:7/24/2014)... sophisticated equipment, trained personnel, and detection dogs to ... attacks. A revolutionary new electronic chip with nano-sized ... much easier. , The groundbreaking nanotechnology-inspired sensor, devised ... ,s School of Chemistry and Center for Nanoscience ... Tracense, picks up the scent of explosives molecules ...
(Date:7/24/2014)... computers have yet to materialise. Yet, scientists are ... such computers faster. One such approach relies on ... by applying an electric field. A new study ... coupled quantum dots (TQDs) with electrical impulses can ... example, should TQDs be used as quantum information ...
(Date:7/24/2014)... Although most natural and synthetic processes prefer to ... potential or energyit is within the realm of ... experience constant changes in energy and phases, such ... These conditions allow humans to regulate their body ... rumble with seismic activity. , But even ...
Breaking Biology Technology:Asterias Biotherapeutics Announces Live Investor Webcast 2Asterias Biotherapeutics Announces Live Investor Webcast 3Asterias Biotherapeutics Announces Live Investor Webcast 4Nano-sized chip 'sniffs out' explosives far better than trained dogs 2New approach to form non-equilibrium structures 2
... conversion of sunlight to electricity could brighten the ... National Laboratory (Berkeley Lab) have found a new ... place in semiconductor thin-films. This new route to ... continues to plague conventional solid-state solar cells. ...
... ... its 6th annual student award program. , ... SAN DIEGO, CA (Vocus) March 30, 2010 ... for Environmental Health & Sciences Foundation (AEHS Foundation) to recognize talented, emerging environmental ...
... genetic sleight of hand, researcher Xinyao Liu and professor ... coaxed photosynthetic microbes to secrete oilbypassing energy and cost ... appear in this week,s advanced online issue of the ... or PNAS . The challenges of ...
Cached Biology Technology:New path to solar energy via solid-state photovoltaics 2New path to solar energy via solid-state photovoltaics 3Association for Environmental Health & Sciences Foundation and Adventus Group Recognize Future Environmental Science Leaders 2Association for Environmental Health & Sciences Foundation and Adventus Group Recognize Future Environmental Science Leaders 3Association for Environmental Health & Sciences Foundation and Adventus Group Recognize Future Environmental Science Leaders 4Microbes reprogrammed to ooze oil for renewable biofuel 2Microbes reprogrammed to ooze oil for renewable biofuel 3
... Immunogen: Immunogen corresponds to amino ... human SKAP55.,PA1-525 has been successfully used in ... By Western blot, this antibody detects an ... cells.This antibody has also been used in ...
... to suit the widest possible range of ... laboratory. Labware carriers can be placed at ... simple for the user, thanks to a ... correctly guided into position. This allows easy ...
... was developed in the late 1960s by ... the earliest commercial pioneers of immunoassay in ... in 1987. Sac-Cel rapidly found favour with ... "in house" radioimmunoassays, and became a benchmark ...
... (3-D-Gluconamidopropyl)deoxycholamide White solid. HYGROSCOPIC. A ... Has reduced electrostatic interactions that do not ... Aggregation number: 8-16. Purity: ≥95% by ... Aggregation number 8 - 16, CMC 1.1 ...
Biology Products: