Navigation Links
New tuberculosis test more than skin deep
Date:6/5/2014

A new screening process for tuberculosis (TB) infections in Canadian prisons could mean that more than 50 per cent of those screened won't undergo unnecessary treatment due to false positives.

According to research by Wendy Wobeser and medical resident Ilan Schwartz, a test for TB using interferon-gamma release assays (IGRA) will detect a pre-existing TB infection, or latent TB, that might not present itself for many years, or until the body becomes weakened by another source.

"It's fairly uncommon that latent TB will reactivate only about a 10 per cent chance," says Dr. Wobeser, the study's lead author and an infectious diseases expert at Queen's. "That said, given the crowding in corrections facilities, the mass exposure of inmates to TB could be disastrous."

The IGRA test was developed in the last 10-15 years and diagnoses a latent TB infection. The body's immune system is provoked with a small amount of protein from the TB virus and if the body has previously been infected then a reaction will occur and the patient's blood will test positive for TB.

The pre-existing tuberculosis skin test (TST) for TB has been used for over 100 years but comes with two main limitations.

  • The current test requires two visits to determine the results: one to perform the test and then another visit a couple of days later to read the results.
  • Depending on the patient's exposure to other mycobacteria or the BCG vaccine, the current TB test can give many false positives.

The study group included representation from Public Health Agency of Canada (PHAC), Public Health Ontario (PHO), Correctional Services Canada (CSC) and the local public health agency. Inmates were tested at a Canadian intake institution before moving on to different corrections facilities. Ninety-six inmates tested positive for TB via the TST test. Only 31 of these inmates were confirmed as true latent TB infection when using the IGRA test.

"Wh
'/>"/>

Contact: Rosie Hales
rosie.hales@queensu.ca
613-533-6000 x77513
Queen's University
Source:Eurekalert

Page: 1 2

Related biology news :

1. Biosignatures distinguish between tuberculosis and sarcoidosis
2. Targeting tuberculosis hotspots could have widespread benefit
3. MIT-designed cooler preserves tuberculosis drugs, records doses
4. Research on improvements in diagnosing and treating tuberculosis
5. Millions of diabetics could die of tuberculosis
6. New approach of resistant tuberculosis
7. Iowa State, Ames Lab researchers study the structure of drug resistance in tuberculosis
8. High doses of Vitamin D help tuberculosis patients recover more quickly
9. Scientists reveal how natural antibiotic kills tuberculosis bacterium
10. Notre Dame research could provide new insights into tuberculosis and other diseases
11. Missing link discovered in the defence mechanism of the tuberculosis pathogen
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/9/2015)... Calif. , April 9, 2015 Synaptics ... interface solutions, announced today that it will report financial ... Thursday, April 23, 2015, after the close of market. ... analysts and investors at 2:00 p.m. PT (5:00 p.m. ... To participate on the live call, analysts ...
(Date:4/6/2015)... Apr. 6, 2015 NXT-ID, Inc. (NASDAQ: ... authentication company focused on the growing mobile commerce ... patent 62/143028 for MINIATURE, MULTI-PURPOSE ANTENNA ... NXT-ID introduces a new revolutionary method ... surrounds the use of miniature antenna modules for ...
(Date:4/2/2015)... April 2, 2015 At its 2015 ACMG ... City , the American College of Medical Genetics ... directors to its Board.  Members of the ACMG Board ... for forming and advancing its policies and programs. ACMG ... "It,s an eventful time in medical genetics ...
Breaking Biology News(10 mins):Synaptics to Report Third Quarter Results on April 23 2NXT-ID Patents Miniature, Low Power Wireless Magnetic Stripe 2NXT-ID Patents Miniature, Low Power Wireless Magnetic Stripe 3NXT-ID Patents Miniature, Low Power Wireless Magnetic Stripe 4American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 2American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 3American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 4American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 5American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 6American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 7American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 8
... ago inhabited savannas -- grassy plains dotted with trees and ... earth science Naomi Levin of The Johns Hopkins University,s Krieger ... at odds with a theory which holds that these ... forth by prominent University of California at Berkeley researcher Tim ...
... The title sounds like a crime novel on a dime-store ... meaning. And the prime suspect is very, very small. ... that the first cells to starve in a slime mold seem ... reproduce, but also pushes those that keep on eating into sacrificing ...
... Climate change is about more than just polar ... whose research into climate change communication has been published ... the efforts of journalists, campaigners and politicians to engage ... ,visual strategies, can communicate climate change messages against a ...
Cached Biology News:Early human habitat was savanna, not forest 2A Dicty mystery solved 2Beyond polar bears? Experts look for a new vision of climate change to combat skepticism 2
(Date:5/5/2015)... 2015 The Academy of Model Aeronautics ... led by Indiana Gov. Mike Pence, has declared August ... will host a Family Fest and aviation themed Motorcycle ... benefit the Wounded Warrior Project. , National Model Aviation ... Aeronautics—the country’s foremost organization for model aviation—to celebrate the ...
(Date:5/5/2015)... 5, 2015 ImmunoCellular Therapeutics, Ltd. ("ImmunoCellular") ... , President and Chief Executive Officer, will present ... DATE:  Thursday, May 7, 2015     TIME:  11:30 am ... > click the red "register/ watch presentations" button ... online event where investors are invited to ask ...
(Date:5/5/2015)... 05, 2015 Franz Inc ., the ... announced that its flagship product, AllegroGraph, has been named a ... Market Update report. AllegroGraph is a high performance ... industry standards. Graph databases are skyrocketing in popularity and have ... a recent DBMS ranking by DB-Engines. , “We ...
(Date:5/5/2015)... 5, 2015 CytomX, a biotechnology company developing ... that Sean McCarthy , D. Phil., chief executive ... in New York at 1:15 ... present an overview of CytomX,s Probody pipeline, including the ... About CytomX Therapeutics CytomX Therapeutics develops ...
Breaking Biology Technology:State of Indiana proclaims August 15 as Model Aviation Day 2ImmunoCellular Therapeutics to Webcast Live at VirtualInvestorConferences.com on May 7 2Bloor Research Positions AllegroGraph as a ‘Champion’ in Burgeoning Graph Database Market 2Bloor Research Positions AllegroGraph as a ‘Champion’ in Burgeoning Graph Database Market 3
... May 26, 2010 , , ... - Study Data Shows ORMD-0801 Resulted in Glucose and C-Peptide Reduction , ... Oramed Pharmaceuticals Inc. (OTCBB: ORMP.OB) ( ... study to assess the safety and pharmacodynamics,of five oral insulin formulations in healthy subjects," ...
... 26 /PRNewswire-FirstCall/ - Oncolytics Biotech Inc. ("Oncolytics") (TSX:ONC, ... & Research Center at the University of Texas ... (CTRC) has started patient enrolment in a U.S. Phase ... combination with gemcitabine (Gemzar(R)) in patients with advanced pancreatic ...
... LONDON , May 26 ... announces the issuance of United States patent ... Treatment of Cancer and Other Neovascularization Disease, by the ... patent, which deepens the Company,s diverse portfolio of RNA ...
Cached Biology Technology:Oramed Pharmaceuticals Announces Publication of Research Article on its Oral Insulin Capsule ORMD-0801 in Diabetes, Obesity and Metabolism 2Oramed Pharmaceuticals Announces Publication of Research Article on its Oral Insulin Capsule ORMD-0801 in Diabetes, Obesity and Metabolism 3Oncolytics Biotech(R) Inc. Announces Start of Enrolment in U.S. Phase 2 Pancreatic Cancer Clinical Trial 2Oncolytics Biotech(R) Inc. Announces Start of Enrolment in U.S. Phase 2 Pancreatic Cancer Clinical Trial 3Oncolytics Biotech(R) Inc. Announces Start of Enrolment in U.S. Phase 2 Pancreatic Cancer Clinical Trial 4Silence Therapeutics Issued Novel RNAi Patent Covering High-Value Cancer Target in United States 2Silence Therapeutics Issued Novel RNAi Patent Covering High-Value Cancer Target in United States 3Silence Therapeutics Issued Novel RNAi Patent Covering High-Value Cancer Target in United States 4
...
... kit contains sufficient materials for 1,464 array sample elements. ... each , Blocker BSA in PBS ... Antibody, HRP-conjugated: 10 g , BupH ... 10% Tween-20: 2 x 10 ml ampules , ...
... Clean and Accurate Results Laser Capture ... the sensitivity and accuracy of molecular assays ... types and multi-cellular structures isolated from whole ... to microdissection-developed in 1996 at the National ...
Mouse monoclonal antibody raised against a partial recombinant DHX8. NCBI Entrez Gene ID = DHX8...
Biology Products: