Navigation Links
New treatment offers hope for short-bowel syndrome patients
Date:7/18/2013

Bethesda, MD (July 18, 2013) A new drug, teduglutide, offers significant relief for patients with short-bowel syndrome intestinal failure who are reliant on intravenous nutrition, according to a new study in Clinical Gastroenterology and Hepatology, the official clinical practice journal of the American Gastroenterological Association. Patients with this relatively rare condition experience massive bowel loss and are unable to absorb nutrients, vitamins and water from digested foods. They rely on parenteral nutrition, or intravenous feeding, to deliver their daily nutrients.

"Short-bowel syndrome is a devastating condition, and without parenteral nutrition patients would not survive. However, this treatment method is labor-intensive, expensive and carries complications, including chronic infection, blood clots and liver failure," said Stephen J. D. O'Keefe, MD, MSc, FRCP, Division of Gastroenterology, University of Pittsburgh Medical School, PA, and lead study author. "Teduglutide, a new form of therapy, offers potential to significantly reduce intravenous nutrition dependency and improve the quality of life for patients."

Teduglutide is an injection administered once daily that helps improve intestinal absorption of fluids and nutrients, reducing the frequency and volume of parenteral nutrition.

Dr. O'Keefe and colleagues conducted a year-long trial to determine the safety, tolerability and clinical efficacy of teduglutide on patients with short-bowel syndrome. After 52 weeks, 68 percent of patients on just a low dose of teduglutide experienced lessened parenteral nutrition dependency and there was a greater than 20 percent reduction in IV-fluid requirements.

Remarkably, the study documented multiple patients who received complete independence from parenteral nutrition. These findings instill hope that short-bowel syndrome patients can achieve a significantly enhanced quality of life, free of sleep disturbances and limited social activities.

Teduglutide recently received FDA approval for individuals with short-bowel syndrome who are dependent on parenteral nutrition or intravenous therapy despite optimal medical management. There are no contraindications and no time limit on therapy. Physicians planning to prescribe the drug need to be knowledgeable in its use and potential side effects, which include gastrointestinal symptoms (abdominal pain, nausea, vomiting), headache and common cold-like symptoms. Further studies are needed to assess teduglutide's safety and efficacy long term.


'/>"/>

Contact: Rachel Steigerwald
media@gastro.org
301-272-1603
American Gastroenterological Association
Source:Eurekalert

Related biology news :

1. Molecular discovery puts cancer treatment in a new perspective
2. Which Prostate Cancers Really Need Treatment?
3. Lifesaving HIV treatment could reach millions more people following landmark study
4. Continued research needed on treatment for women with lung cancer who are never smokers
5. Artificial sweetener a potential treatment for Parkinsons disease
6. Posttraumatic stress disorder treatment: Genetic predictor of response to exposure therapy
7. Scientists identify potential drug target for treatment-resistant anemias
8. Neurochemical traffic signals may open new avenues for the treatment of schizophrenia
9. Addition of bevacizumab to initial treatment for brain tumors does not extend patients lives
10. Engineered stem cell advance points toward treatment for ALS
11. Using big data to identify prostate cancers and best treatments
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/23/2017)... ARMONK, N.Y. and ITHACA, N.Y. ... IBM ) and Cornell University, a leader in dairy ... combined with bioinformatics designed to help reduce the chances ... breaches. With the onset of this dairy project, Cornell ... the Consortium for Sequencing the Food Supply Chain, a ...
(Date:5/23/2017)... , May 23, 2017  Hunova, the first robotic gym for ... has been officially launched in Genoa, Italy . The ... and the USA . The technology was ... the market by the IIT spin-off Movendo Technology thanks to a 10 ... Multimedia News Release, please click: ...
(Date:5/16/2017)... 16, 2017   Bridge Patient Portal , ... MD EMR Systems , an electronic medical ... GE, have established a partnership to build an ... the GE Centricity™ products, including Centricity Practice Solution ... These new integrations will allow healthcare delivery ...
Breaking Biology News(10 mins):
(Date:7/18/2017)... New Jersey (PRWEB) , ... July 18, 2017 , ... ... that aligns with your needs and has the capabilities to properly execute your job ... site customglassparts.com is a sourcing portal designed to showcase the company’s ...
(Date:7/18/2017)... ... July 18, 2017 , ... ... and has released the first phase of the Allotrope Framework for commercial use. ... Awards were created to “not only elevate the critical role of information technology ...
(Date:7/17/2017)... ... July 17, 2017 , ... ... software company AB Cube has joined its eHealth App xChange ™, ... innovation across life sciences and healthcare. Under the partnership, AB Cube’s comprehensive, ...
(Date:7/17/2017)... (PRWEB) , ... July 17, 2017 , ... ... diagnostics company that has developed and intends both to manufacture and sell reagents ... on the NASDAQ Capital Market. , Headquartered in Sandy, Utah, Co-Diagnostics’ intellectual property ...
Breaking Biology Technology: