Navigation Links
New therapy for heart failure may enhance body's stem cell response at cardiovascular injury site
Date:2/21/2013

TAMPA, Florida (Feb. 21, 2013) Cardiovascular disease specialists at Florida Hospital Pepin Heart Institute and Dr. Kiran C. Patel Research Institute affiliated with the University of South Florida announced they have enrolled their first patients into a clinical trial testing a novel gene therapy for the treatment of heart failure after ischemic injury. The therapy may promote the regeneration of heart tissue by encouraging the body to deploy more stem cells to the injury site.

Dr. Charles Lambert, Medical Director of Florida Hospital Pepin Heart Institute and Dr. Leslie Miller, Director of the USF Heart Institute, are leading the way for the randomized, placebo-controlled trial which spans 10 sites across the United States. The study, called the STOP-HF, will enroll 90 patients nationwide.

Heart failure (HF) can occur when the muscles of the heart become weakened and cannot pump blood sufficiently throughout the body. The injury is most often caused by inadequate blood flow to the heart resulting from chronic or acute cardiovascular disease, including heart attacks. Considerable scientific evidence has emerged over the past decade demonstrating the high therapeutic potential of regenerative medicine for a host of diseases. Heart failure is a leading cause of death, disability and hospitalization.

Dr. Charles Lambert is performing the gene therapy by direct injection into the heart using an investigational system in the catheterization laboratories at Florida Hospital Pepin Heart Institute.

"Pepin Heart and Dr. Kiran C. Patel Research Institute and USF are exploring and conducting leading-edge research to develop break-through treatments long before they are even available in other facilities," Dr. Lambert said. "Stem cells have the unique ability to develop into many different cell types, and in many tissues serve as an internal repair system, dividing essentially without limit to replenish other cells. This tria
'/>"/>

Contact: Anne DeLotto Baier
abaier@health.usf.edu
813-974-3303
University of South Florida (USF Health)
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Cell therapy a little more concrete thanks to VIB research
2. Preclinical study shows potential of new technologies to detect response to cancer therapy earlier
3. Novel coronavirus well-adapted to humans, susceptible to immunotherapy
4. Experimental gene therapy treatment for Duchenne muscular dystrophy offers hope for youngster
5. Compound stimulates tumor-fighting protein in cancer therapy
6. VEGF Inhibition: Therapy-Indicating and Prognostic Biomarkers, 2013
7. Pitt researchers reveal mechanism to halt cancer cell growth, discover potential therapy
8. Changes to DNA on-off switches affect cells ability to repair breaks, respond to chemotherapy
9. BUSM study shows potential of differentiated iPS cells in cell therapy without immune rejection
10. Canada launches first gene therapy trial for Fabry disease
11. New way to kill lymphoma without chemotherapy
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New therapy for heart failure may enhance body's stem cell response at cardiovascular injury site
(Date:12/19/2014)... 2014 Research and Markets ( http://www.researchandmarkets.com/research/8kmfcn/iphone_5s ) ... Fingerprint Sensor - Apple/AuthenTec TMDR92 & Sapphire - Technology ... http://photos.prnewswire.com/prnh/20130307/600769 Following the acquisition ... reading feature with the iPhone 5S. It is currently ...
(Date:12/17/2014)... BELVOIR, Va. , Dec. 15, 2014 The ... it easier to detect and prevent counterfeit microcircuits from ... agency started performing an in-house microcircuit anti-counterfeit initiative dubbed ... purchased microcircuits while increasing their reliability throughout the supply ...
(Date:12/15/2014)... DUBLIN , Dec. 12, 2014 Research and Markets ... of the "Global Facial Recognition Market 2015-2019" ... http://photos.prnewswire.com/prnh/20130307/600769 Facial recognition is a technology ... measures the overall facial feature of a person such ...
Breaking Biology News(10 mins):iPhone 5S Fingerprint Sensor - Apple/AuthenTec TMDR92 & Sapphire - Technology Report 2Defense Logistics Agency Launches DNA Marking Capability to Strengthen Microcircuit Supply Chain 2Defense Logistics Agency Launches DNA Marking Capability to Strengthen Microcircuit Supply Chain 3Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 2Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 3
... Researchers at the University of Cambridge have discovered a ... within the body, a breakthrough that could lead to ... , Dr. Pietro Mastroeni, Professor Duncan Maskell at ... pioneered the integration of mathematical models with observational data ...
... had narrow, pointed teeth, which were more suited to tearing ... then grind their food? Until recently many researchers have assumed ... their muscular stomach these then acted as a kind of ... correct, as scientists at the universities of Bonn and Tübingen ...
... regulate neuronal signaling in the brain and spinal cord ... mouse with a mutation affecting a neuronal zinc target, ... modulating signaling among the neurons. Significantly, they found the ... as children with the genetic disorder called "startle disease," ...
Cached Biology News:Researchers map spread of pathogens in the human body 2Dinosaurs -- stones did not help with digestion 2Dinosaurs -- stones did not help with digestion 3Zinc plays important role in brain circuitry 2
(Date:1/22/2015)... today announces the firm brokered a long-term lease totaling 202,492 ... company, at Two Ledgemont Center in Lexington, Massachusetts ... and Brian Cohen , senior vice president, represented Shire ... Hayden Ave. Photo - http://photos.prnewswire.com/prnh/20150122/170765 ...
(Date:1/22/2015)... 2015 Pipette.com has added the ... comprehensive portfolio of Eppendorf products. , The Eppendorf Centrifuge ... Centrifuge 5424/5424 R and receive the following:, ... plus or Eppendorf Reference 2 ,     3 ...
(Date:1/22/2015)... Denville, NJ (PRWEB) January 22, 2015 ... shearing technologies such as the Bioruptor® and complete ... semi-automation system for chromatin immunoprecipitation, alleviating the need ... reagents and controls needed for ChIP of histones ...
(Date:1/22/2015)... , Jan. 22, 2015  Derma Sciences, Inc. ... company focused on advanced wound care, announces that ... tissues, have been added to the Premier, Inc. ... the opportunity for the AMNIOEXCEL® and AMNIOMATRIX® product ...
Breaking Biology Technology:Transwestern?RBJ Advises Shire in 202,000 SF Lease, Creating Boston's Largest Suburban Biotech Campus 2Eppendorf Announces Promotional Bundle Which Includes: Eppendorf Centrifuge 5424, 3-Pack of Pipettes, and Tips - Available Now at Pipette.com 2Diagenode Launches Unique Semi-Automated Solution for Chromatin Immunoprecipitation 2Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 2Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 3Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 4Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 5
... Businesses Find the ... Best Leaders, ... is featured in the September issue of New Jersey Business magazine.,The ... Association (NJBIA), the largest state employer organization in,the country. The article, ...
... N.C., Sept. 5 A study in ... the use of the GlycoMark,1,5-anhydroglucitol (1,5-AG) blood ... especially to target postprandial hyperglycemia (elevated,after-meal glucose ... achieving optimal glycemic control and reducing the ...
... CRY ),a biomaterials, medical device and tissue ... vice president, chief operating officer,and chief financial officer ... Bear Stearns 20th Annual Healthcare Conference on Monday, ... will also present at the First Albany,Capital Regenerative ...
Cached Biology Technology:Boyden's Summit Practice Featured in the September Issue of New Jersey Business Magazine 2Study Supports Use of GlycoMark Blood Test to Evaluate Therapy in Children with Diabetes 2
...
GLP expression profiling service on the Affymetrix platform. Starting material can be blood, tissue or RNA. 5 day turnaround. Standard and custom post analyses of microarray data available....
... enables early selection of the best ... quantitative data for sensitivity, dynamic range, ... Furthermore quantitative antibody fingerprints can be ... your antibodies., The full-service package includes ...
... allows for rapid, convenient, and efficient Denatured ... process utilizes a spin column to make ... concentration of proteins which were electro-eluted in ... ion exchangers, offering high binding capacity fo ...
Biology Products: