Navigation Links
New technology to improve early detection and prognosis of cancer
Date:3/24/2011

Grand Rapids, Mich. (March 24, 2011) Gentel Biosciences, a leader in proteomics tools, and Van Andel Research Institute (VARI), a biomedical research institute, jointly announce today the granting of U.S. Patent 7,838,634 for a new method to profile changes in the glycosylation of proteins captured on the surface of an antibody array slide. Gentel first obtained an exclusive right to commercialize the technology in 2006.

According to Brian H. Haab, Ph.D., head of VARI's Laboratory of Cancer Immunodiagnostics and inventor of the technology, "A number of new biomarkers using glycosylated variants of proteins have recently received or are proceeding toward FDA clearance. The ability to efficiently screen glycosylated variants of many proteins for use as biomarkers offers an unprecedented opportunity for discoveries of new glycan-based biomarkers."

Glycosylation is the addition of linear or branched sugar molecules to proteins. Many studies have shown that glycosylated variants of proteins can make better markers for early detection and for prognosis in cancers like hepatocellular carcinoma when compared to measuring the protein alone.

"There is a lack of tools to screen proteins for changes in glycosylation that might be associated with disease. Dr. Haab's approach is a better method to identify new diagnostic biomarkers based on glycosylated variants of proteins," added Bryce P. Nelson, Ph.D., Vice President of Technology and Business Development at Gentel Biosciences.

A patent for the technology is also pending in the European Union.

The new glycan detection technology will soon be combined with the more than fifty SilverQuant Antibody Array kits available from Gentel. These antibody array kits target nearly 500 proteins and provide a complete proteomics workflow from screening to quantification. SilverQuant kits are configured for use with the Gentel Proteomics Multi-System and Gentel's AthenaQuant analysis software for an easy-to-use and cost-effective alternative with better sensitivity than fluorescence-based detection. SilverQuant chromogenic technology allows for the detection of any biotinylated molecule, generating array spots that are visible to the naked eye that can be detected with the Gentel Proteomics Multi-System. Simple protocols empower both experts and novices to obtain meaningful protein multiplexing data in a single day.


'/>"/>

Contact: Joe Gavan
joe.gavan@vai.org
616-234-5390
Van Andel Research Institute
Source:Eurekalert

Related biology news :

1. U of M researchers close in on technology for making renewable petroleum
2. University of Houston wins $1 million EPA grant to test diesel technology on buses
3. AMIA on meaningful use: Invest in people and technology
4. Cleveland Clinic researchers honored for contributions to science and technology
5. DHS Science and Technology Directorates science conference: Catastrophes and Complex Systems
6. NextCAT secures license agreement for advanced biofuel technology from Wayne State
7. New technology pinpoints genetic differences between cancer and non-cancer patients
8. Groundbreaking technology will revolutionize blood pressure measurement
9. Stanford researchers develop new technology for cheaper, more efficient solar cells
10. Immunologist J. John Cohen receives the 2010 AAAS Public Understanding of Science and Technology Award
11. New MegaMatcher 4.0 from Neurotechnology Integrates Fingerprint, Iris, Facial and Palmprint Biometrics In One High-Performance SDK
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/30/2017)... -- On April 6-7, 2017, Sequencing.com will host the world,s ... at Microsoft,s headquarters in Redmond, Washington ... health and wellness apps that provide a unique, personalized ... is the first hackathon for personal genomics and the ... the genomics, tech and health industries are sending teams ...
(Date:3/30/2017)... Trends, opportunities and forecast in this market ... (fingerprint, AFIS, iris recognition, facial recognition, hand geometry, vein ... use industry (government and law enforcement, commercial and retail, ... others), and by region ( North America ... Pacific , and the Rest of the World) ...
(Date:3/28/2017)... The report "Video Surveillance Market ... Storage Devices), Software (Video Analytics, VMS), and Service (VSaaS, ... to 2022", published by MarketsandMarkets, the market was valued ... to reach USD 75.64 Billion by 2022, at a ... year considered for the study is 2016 and the ...
Breaking Biology News(10 mins):
(Date:6/23/2017)... (PRWEB) , ... June 23, ... ... the launch of a redesigned, easier-to-navigate website for all six of their ... for physicians, nurses, dentists, pharmacists, physical and occupational therapists, and biotechnicians, DocCafe.com ...
(Date:6/22/2017)... ... June 22, 2017 , ... AESKU.GROUP, an ... Diagnostische Systeme & Technologien GmbH, thereby expanding its product portfolio to include allergy ... fever, urticaria, asthma, atopic eczema or a food allergy. Allergies are escalating to ...
(Date:6/22/2017)... MD (PRWEB) , ... June 22, 2017 , ... ... solutions provider, announced the release of Limfinity® version 6.5, a content-packed update to ... framework continue to gain a larger and more diverse base of customers among ...
(Date:6/20/2017)... 20, 2017  Kibow Biotech Inc., a pioneer in ... issuance of a new patent covering a unique method ... U.S. Patent and Trademark Office on May 23 rd ... Buzz of Bio award in 2014 in ... non-drug approaches to chronic disease. Renadylâ„¢, the first and ...
Breaking Biology Technology: