Navigation Links
New technology for boosting vaccine efficiency
Date:4/24/2008

One of the most pressing biomedical issues is the development of techniques that increase the efficiency of vaccines. In a paper published on April 24, 2008 in the journal Vaccine, a Massachusettss biotechnology company, Cure Lab, Inc. has proposed a new technology for anti-viral vaccination. This technology consists of two major elements. First, each vaccine antigen should be made in two forms. One is easily processed within the organisms cells by an intracellular chopping machine called the proteosome, while another is resistant to the chopping. Thus both these forms of an antigen would be used in combination to elicit a much stronger immune response than either of them would be able to do alone.

Imagine a vaccine that could make a cell within our body produce a viral protein. This is called a recombinant vaccine. Recombinant vaccines give the most hope today as anti-viral and anti-cancer vaccines. They train the immune system to recognize and eliminate first infected or cancerous cells, preventing a disease progression. In order for a recombinant vaccine to be effective, the produced viral protein must be presented by the cell to our immune system. This antigen presentation process is very complex and remains poorly understood.

A few years ago the situation seemed to be simple- said Dr. Alex Shneider, Founder and CEO of Cure Lab, Inc. - Vaccinologists believed that a recombinant vaccine makes the cell able to produce a viral protein. The proteosome cuts this protein into pieces. These pieces are then presented on the cell surface and stimulate immunity. If this was the complete story, life-saving solutions would be so close. A lot of research groups rushed to enhance their vaccines by fusing different viral proteins used in vaccines with specific transport signals directing the proteins to the proteosome. The logic was pretty straightforward. The more protein that would be targeted to a proteosome, the more protein segments generated for
'/>"/>

Contact: Alex Shneider
thoidis@curelab.com
609-841-1201
Cure Lab, Inc.
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Yale scientists use nanotechnology to fight E. coli
2. Voice Biometrics Gains Traction as Most Accurate and Convenient Technology to Secure Customer Privacy
3. M2SYS Partners with SecuGen Corporation to Support Market Leading Hamster Plus Fingerprint Reader with Auto-On Technology
4. Silicon Valley Technology Leaders LaserCard Corporation and Tesla Motors Sign LaserPass Secure Access Deal
5. Nanotechnology: Whats that?
6. UCs NIH grant brings technology from outer space to playgrounds
7. BIO-key(R) International to Showcase Deployed Biometric Security Applications at 2007 Biometric Technology Expo
8. Cogent Systems and Northrop Grumman Reach Agreement to Settle Automated Fingerprint Identification Technology Suit and Create Strategic Alliance
9. UCLA/VA partners with ASU to advance biosensor technology for urinary tract infections
10. Herr receives Heinz Award for Technology, the Economy and Employment
11. Singapore National Science and Technology Awards
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/23/2014)... store four times more carbon than the atmosphere ... have a big effect on atmospheric greenhouse gas ... Nature Climate Change concludes that climate warming ... affect soil carbon storage, despite increases in ecosystem ... Forest Service Research Ecologist Dr. Christian Giardina, with ...
(Date:9/23/2014)... Scientists often measure the effects of temperature on insects ... and abundance, but a Dartmouth study shows for the ... addition to temperature, ultimately limits how fast they grow. ... more about the overall environmental conditions that shape the ... lead author Lauren Culler , an Arctic postdoctoral ...
(Date:9/23/2014)... today that the Company has secured $21 million in ... used to expand the Company,s cancer immunotherapy pipeline and ... Yuan Capital led the round, with participation from Majuven ... Suma Venture and Harbinger Venture Capital. , Eureka ... antibodies engineered to mimic the functions of a T ...
Breaking Biology News(10 mins):Study helps assess impact of temperature on belowground soil decomposition 2Insects' fear limits boost from climate change, Dartmouth study shows 2
... in the Journal of Proteome Research, authored by ... GmbH, Rosetta Inpharmatics LLC, CXR Biosciences Ltd, the ... synergisms and enhanced analytic power of the combination ... proprietary microarray analysis methods of Genomatix Software GmbH., ...
... The Ohio State University have demonstrated that Target Region ... preserving the important genetic diversity of ornamental flower collections. ... the most popular flowers the world. So popular, in ... 3,000 varieties of geranium in their 2004 distribution catalogue. ...
... common dietary molecules found in legumes and bran ... radiation, researchers from the University of Maryland report. ... skin cells and a skin cancer-prone mouse from ... radiation found in sunlight, the team reported today ...
Cached Biology News:'TRAP' preserves genetic properties of popular geranium 2Antioxidants could provide all-purpose radiation protection 2Antioxidants could provide all-purpose radiation protection 3
(Date:9/23/2014)... Calif. , Sept. 23, 2014 ... in India devoted to genome-based research ... Biomedical Genomics (NIBMG) is taking a bite out of ... cancer among males in India with ... storage solutions from DataDirect Networks (DDN). , To fuel ...
(Date:9/23/2014)... --  GenoSpace , a precision medicine software company that ... the broad use of genomic data in research and ... Phase I of a Fast Track Small Business Innovation ... (NIH) to enable enhanced data access and cohort construction ... During the past decade, the cost ...
(Date:9/23/2014)... September 23, 2014 Dr. Williams says, ... book on healthcare offers a three phase process that ... healthcare delivery system that would go far beyond anything ... regarding the delivery of healthcare.” , “Every effort to ... failed to provide discernable progress throughout that system because ...
(Date:9/22/2014)... 22, 2014 Patients who were treated with a statin ... were significantly more likely to survive than those who ... JAMA Neurology . This study was conducted by ... of cholesterol-lowering statins can improve survival in victims of ... or obstruction of a blood vessel that blocks blood ...
Breaking Biology Technology:National Institute of Biomedical Genomics (NIBMG) Deploys DataDirect Networks Storage to Achieve Significant Performance Improvement in World-Class Genomics Research and Collaboration for Oral Cancer 2National Institute of Biomedical Genomics (NIBMG) Deploys DataDirect Networks Storage to Achieve Significant Performance Improvement in World-Class Genomics Research and Collaboration for Oral Cancer 3National Institute of Biomedical Genomics (NIBMG) Deploys DataDirect Networks Storage to Achieve Significant Performance Improvement in World-Class Genomics Research and Collaboration for Oral Cancer 4National Institute of Biomedical Genomics (NIBMG) Deploys DataDirect Networks Storage to Achieve Significant Performance Improvement in World-Class Genomics Research and Collaboration for Oral Cancer 5GenoSpace Awarded Fast Track SBIR Grant to Enable Data Access and Cohort Construction for Biorepositories 2Dr. Ira Williams Offers the Healthcare Solution Necessary for Patient Safety Improvement 2Statin use during hospitalization for hemorrhagic stroke associated with improved survival 2
... SAN FRANCISCO, Calif., Aug. 23 Monogram,Biosciences, Inc. (Nasdaq: ... CEO,and Chairman, is scheduled to present a corporate overview ... September 5, 2007,at 3:15 p.m. (Eastern Time) at the ... live audio broadcast or the subsequent archived,recording, log on ...
... (Nasdaq: KNDL ), a,leading, global full-service clinical ... 10th anniversary as a public company by,ringing the ... also marked the,anniversary with an Investor Day at ... and shareholders the company,s perspective on the,latest industry ...
... Initiative to Pursue Cures for Patients, ... controversial Human Cloning, WASHINGTON, Aug. 22 Today, a ... taxpayer funds,support cures for patients, without involving human cloning. ... statement on the new initiative, Cures Without Cloning. "I ...
Cached Biology Technology:Monogram Biosciences to Present at the Thomas Weisel Partners Healthcare Conference 2007 2Kendle Marks 10th Anniversary as Public Company With NASDAQ Opening Bell Ceremony and Investor Day Event 2Kendle Marks 10th Anniversary as Public Company With NASDAQ Opening Bell Ceremony and Investor Day Event 3Kendle Marks 10th Anniversary as Public Company With NASDAQ Opening Bell Ceremony and Investor Day Event 4Kendle Marks 10th Anniversary as Public Company With NASDAQ Opening Bell Ceremony and Investor Day Event 5
... is the simplest, easiest-to-use system ever for ... handling capabilities,into their labs, or groups in ... applications on a separate instrument. Plate-handling is ... even when you have thousands of samples., ...
... Safe Deposit Service ECACC is able to accept ... cGMP for cryo-storage. The cell lines must be ... been produced in accordance with the requirements of ... freedom from mycoplasma, bacteria or fungi. What are ...
... provides cost effective cell culture services for ... antibodies. Quality at a reasonable price is ... research or commercial product, we strive toward ... as roller bottles, hollow fiber, and bioreactor ...
... Cell Bank Service The Human Genetic ... Epstein-Barr Virus (EBV) immortalisation of human peripheral ... of lymphoblastoid cell lines (LCLs). These cell ... and expandable source of genomic DNA and ...
Biology Products: