Navigation Links
New technology enhances therapeutic potential of cord blood stem cells
Date:6/6/2008

A CD26 Inhibitor increases the efficiency and responsiveness of umbilical cord blood for bone marrow transplants and may improve care for blood cancer patients according to research from Rush University Medical Center being presented at the 6th Annual International Umbilical Cord Blood Transplantation Symposium, June 6-7 in Los Angeles.

Kent W. Christopherson II, PhD, assistant professor of medicine and researcher in the Sections of Hematology and Stem Cell Transplantation at Rush, is researching a CD26 Inhibitor, a small molecule enzyme inhibitor that enhances directional homing of stem cells to the bone marrow by increasing the responsiveness of donor stem cells to a natural homing signal. Homing is the process by which the donor stem cells find their way to the bone marrow. It is the first and essential step in stem cell transplantation.

Cord blood is increasingly being used by transplant centers as an alternative source of stem cells for the treatment of blood cancers, including myeloma, lymphoma and leukemia. The cells, which are collected from the umbilical cord after the baby is delivered and separated from the cord, are most commonly used for bone marrow transplantation when a donor from a patient's family or an unrelated donor does not produce an appropriate bone marrow match.

The current drawback to the usage of cord blood cells is that due to the limited volume and cell number, there are generally only enough cells available from a single cord blood collection for children or very small adults. Cord blood cells also usually take longer to engraft, leaving the patient at a high risk for infection longer than donor matched transplanted marrow or peripheral blood stem cells. The goal of Christopherson's research is to increase the transplant efficiency of umbilical cord blood and ultimately make transplant safer and available to all patients who require this treatment.

In his discussion on "Strategies to Improve Homi
'/>"/>

Contact: Kim Waterman
Kimberly_Waterman@rush.edu
312-942-7820
Rush University Medical Center
Source:Eurekalert

Page: 1 2

Related biology news :

1. bioMETRX, Inc. Partners with Biometric Solutions, LLC to Deliver Next Generation Finger Activated Technology
2. Synergy between biology and physics drives cell-imaging technology
3. Brown to host conference on advances in neurotechnology
4. DHS, business leaders discuss technology to protect US at Homeland Security conference
5. Scripps Research Institute awarded patent for remarkable chemical technology
6. Neurotechnology Announces MegaMatcher 2.1 SDK for Development of Large-scale AFIS and Multi-biometric Face-Fingerprint Identification Systems
7. IEEE Homeland Security Conference Business Panel to feature experts on technology commercialization
8. Atmel Receives Frost & Sullivans Technology Innovation Award for FingerChip(R) Biometric Sensor
9. Too much technology may be killing beneficial bacteria
10. Scientists make chemical cousin of DNA for use as new nanotechnology building block
11. BIO-key(R) Granted Image Identification System Patent for Award Winning Biometric Technology
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/31/2015)... DUBLIN , Aug. 31, 2015 Research ... of the "Saudi Arabia Biomedical Sensors Market - ... offering. The Saudi Arabia Biomedical Sensors ... a CAGR of 3.64% over the period 2014-2020 ... are adaptable to the genetic formulation of each individual. ...
(Date:8/24/2015)... Aug. 24, 2015  Based on its recent analysis of ... the 2015 African Biometrics Company of the Year Award. DERMALOG ... commercial success in Africa . It has ... it has implemented one of the largest biometric mass applications ... as the Central Bank of Nigeria ...
(Date:8/18/2015)... , Aug. 18, 2015  Navitas today ... contributor to the Submission Content Management webinar ... a non-profit forum. Dedicated to the Implementation of ... neutral platform for industry, vendors, health authorities, ... and work towards a standard method of ...
Breaking Biology News(10 mins):Saudi Arabia Biomedical Sensors Market Report 2015 - Growth, Trends & Forecasts (2014-2020) 2Frost & Sullivan Applauds DERMALOG's Rise as the Supplier of Best-in-class Biometric Solutions in Africa 2Frost & Sullivan Applauds DERMALOG's Rise as the Supplier of Best-in-class Biometric Solutions in Africa 3Frost & Sullivan Applauds DERMALOG's Rise as the Supplier of Best-in-class Biometric Solutions in Africa 4Frost & Sullivan Applauds DERMALOG's Rise as the Supplier of Best-in-class Biometric Solutions in Africa 5Frost & Sullivan Applauds DERMALOG's Rise as the Supplier of Best-in-class Biometric Solutions in Africa 6Navitas, a Key Contributor in IRISS Forum Webinar 2Navitas, a Key Contributor in IRISS Forum Webinar 3
... In our not-so-distant evolutionary past, stress often meant ... so part of our body,s stress response is ... Medicine Partnership Unit (MMPU), a collaboration between the ... and the University of Heidelberg Medical Centre, have ...
... in the long-standing arms race between the flowering plant ... Duke University researchers have found that the little mustard ... prepare for the greatest onslaught of infectious spores released by ... time of day it is and change their activities accordingly, ...
... PORTLAND, Ore. -- The pediatric cardiac team at Oregon ... first in the region and one of a handful ... without open-heart surgery. To date, four patients have ... Adult Congenital Cardiac Catheterization Lab. All reported immediate improvement ...
Cached Biology News:Blood-clotting protein linked to cancer and septicemia 2Blood-clotting protein linked to cancer and septicemia 3Plant's immune defense revs up for the morning attack 2Plant's immune defense revs up for the morning attack 3OHSU fixes complex heart problems without open-heart surgery 2
(Date:8/30/2015)... England , August 31, 2015 /PRNewswire/ ... 51-jährige Wartezeit   einer Frau   für chirurgische   ... Alter von 7-90   werden für eine ... Programm soll 1200 Frauen behandeln und die Anzahl ausgebildeter ... Astellas gab heute bekannt, dass  Action ...
(Date:8/28/2015)... 28, 2015 According to a ... Cryogenic Storage Systems, Thawing Equipment, Alarms), by Biospecimen (Human ... Trials), End User - Global Forecast to 2020", published ... reach USD 3,731.03 Million by 2020 from USD 2,150.48 ... between 2015 and 2020. Browse 74 ...
(Date:8/28/2015)... , ... August 28, 2015 , ... ... Gardner, has organized and will present a session on chemical spectroscopic imaging at ... conference and exposition is Asia’s largest analytical and scientific instruments show which will ...
(Date:8/28/2015)... , ... August 28, 2015 , ... ... and orthopedic surgeon, Wade McKenna, DO, announced today that the use of sterile, ... resulted in complete healing of an otherwise non-healing surgical knee wound. , The ...
Breaking Biology Technology:Über 550 Frauen, deren Leben durch "Action on Fistula" transformiert wurde 2Über 550 Frauen, deren Leben durch "Action on Fistula" transformiert wurde 3Über 550 Frauen, deren Leben durch "Action on Fistula" transformiert wurde 4Über 550 Frauen, deren Leben durch "Action on Fistula" transformiert wurde 5Biopreservation Market Worth 3,731.03 Million USD by 2020 2Biopreservation Market Worth 3,731.03 Million USD by 2020 3Biopreservation Market Worth 3,731.03 Million USD by 2020 4Biopreservation Market Worth 3,731.03 Million USD by 2020 5U.S. Symposium on Imaging Organized by Pittcon’s Program Chairman Chuck Gardner 2U.S. Symposium on Imaging Organized by Pittcon’s Program Chairman Chuck Gardner 3Dallas-Fort Worth Stem Cell Researchers Use Amniotic Tissue To Successfully Treat Non-Healing Surgical Wound 2Dallas-Fort Worth Stem Cell Researchers Use Amniotic Tissue To Successfully Treat Non-Healing Surgical Wound 3Dallas-Fort Worth Stem Cell Researchers Use Amniotic Tissue To Successfully Treat Non-Healing Surgical Wound 4
... warm business climate,and appealing lifestyle, Florida is fast ... Statewide, Florida,s high-tech industries added 10,900 net jobs ... to Florida Cybercities,2007, a recent report by the ... data available. With a 4 percent growth ...
... N.J., Nov. 15 At a ... Wyeth (NYSE: WYE ), held ... per share on the outstanding shares ... January 2, 2008 to stockholders of ...
... Inc. (OTC Bulletin Board: AIDA) today announced that it,has ... 30, 2007. Net,revenues totaled $7,373,770 for the quarter ended ... 2006. Gross profit decreased by 2.66% due to an,increase ... Aida,s,transfusion and injection forms of etimicin sulfate increased markedly.,Gross ...
Cached Biology Technology:Florida's Technology Sector Attracting Skilled Workers Needing Homes 2Aida Files 10Q 2Aida Files 10Q 3Aida Files 10Q 4
RABBIT ANTI HUMAN APP (KP1 DOMAIN) Immunogen: Synthetic peptide composed of amino acids 292-312 from the KPI domain of human APP....
... The Light Diagnostics Cytomegalovirus (CMV) pp65 ... the qualitative identification of lower matrix protein ... leukocytes. Kit Components: ... 5122) One bottle containing 220 mL of ...
ANTI NO-TRYPTOPHAN CONJUGATE...
ANTI DEOXY CORTICO...
Biology Products: