Navigation Links
New technique tracks proteins in single HIV particle
Date:5/5/2014

on as well as in a human cell infected with it."

"We then used the technique to study both clinically approved and newly developed HIV inhibitors. Some of these drugs were thought to affect interaction between integrase particles. With our new technique, we were able to observe that this was indeed the case."

"There are already a few dozen medications available for HIV, but further research is essential. Whenever HIV multiplies by hijacking an immune cell, there is a chance of mutation, and there is no guarantee that an HIV drug will be able to handle that mutation. A medication may not be as effective over the course of a patient's lifetime. Moreover, current HIV drugs are very expensive. Hence the importance of being able to test anti-HIV medications quickly and efficiently."

The good news is that this new technique can be broadly applied: "It may seem surprising, but we can also use a genetically modified version of a dangerous virus to examine other pathogens. Essentially, we have created a nano test tube out of an HIV virion, inside of which protein interactions can be studied. In principle, we can make any protein fluorescent, be it from HIV, from another disease or from a human cell."

"Researchers have been studying protein interactions for some time, but studying them at the level of a single viral particle was not possible until now," says Jelle Hendrix. Our technique allows scientists to quickly test many molecules potential medications for many diseases using minimal material. In future research, we will be using the technique to study integrase proteins of other viruses."


'/>"/>

Contact: Dr. Jelle Hendrix
jelle.hendrix@chem.kuleuven.be
32-016-327-344
KU Leuven
Source:Eurekalert

Page: 1 2

Related biology news :

1. Ground breaking technique offers DNA Sat Nav direct to your ancestors home 1,000 years ago
2. New technique detects microscopic diabetes-related eye damage
3. New technique will accelerate genetic characterization of photosynthesis
4. New technique takes cues from astronomy and ophthalmology to sharpen microscope images
5. Researchers develop novel molecular blood group typing technique
6. New technique brings us closer to HIV and Hepatitis C vaccines
7. New technique sheds light on human neural networks
8. New technique for identifying gene-enhancers
9. Heat-based technique offers new way to measure microscopic particles
10. NIST microanalysis technique makes the most of small nanoparticle samples
11. New technique makes biogasoline from plant waste
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/27/2015)... , July 27, 2015   Zynx Health ... experience-based clinical improvement solutions, today announced that its ... now available on Android smartphones and tablets. With ... post-care organizations can use ZynxCarebook to securely exchange ... condition, streamline care transitions to other care settings, ...
(Date:7/23/2015)... Research and Markets ( http://www.researchandmarkets.com/research/rzzp3v/global_outlook_of ) ... Outlook of the Biometrics Industry 2015 " ... global biometrics market is likely to witness significant ... to the uptake of multiple technologies available. The ... the growth of biometrics in existing applications as ...
(Date:7/21/2015)... 2015  NXT-ID, Inc. (NASDAQ: NXTD ) ... focused on the growing mobile commerce market and ... it has filed provisional patent 62/192218 for ... This invention highlights next generation payment technology ... but also the user using unique personal identifiers ...
Breaking Biology News(10 mins):Zynx Health Adds Android Device Support to ZynxCarebook Solution 2Zynx Health Adds Android Device Support to ZynxCarebook Solution 3Global Outlook of the Biometrics Industry 2015 2Global Outlook of the Biometrics Industry 2015 3NXT-ID Patents Personalized Tokenized Payments for Next Generation Secure Payment Technology 2NXT-ID Patents Personalized Tokenized Payments for Next Generation Secure Payment Technology 3NXT-ID Patents Personalized Tokenized Payments for Next Generation Secure Payment Technology 4
... This release is available in German . ... disk currently consists of about 3 million magnetic atoms. Researchers ... memory with one bit per molecule. By an electric pulse, ... magnetic state and a low-conductive, non-magnetic state. This novel correlation ...
... in most developing countries to meet the United Nations, ... from hunger by 2015 compared with 1990 levels, according ... and weight, published today in the Lancet . ... improved overall since 1985, one in five infants and ...
... medicine for Parkinson,s disease, by investigating signs of the ... respond to drug treatments. The study was funded by ... skin cells from patients with genetically inherited forms of ... found that neurons derived from individuals with distinct types ...
Cached Biology News:Nature: Molecule changes magnetism and conductance 2Developing world has less than 5 percent chance of meeting UN child hunger target, study estimates 2Developing world has less than 5 percent chance of meeting UN child hunger target, study estimates 3Patient-derived stem cells could improve drug research for Parkinson's 2Patient-derived stem cells could improve drug research for Parkinson's 3Patient-derived stem cells could improve drug research for Parkinson's 4
(Date:7/29/2015)...  HealthSouth Corporation (NYSE: HLS ), one ... services, offering both facility-based and home-based post-acute services, ... second quarter ended June 30, 2015. ... growth in both segments and an 11.0% increase ... and Chief Executive Officer of HealthSouth. "While reported ...
(Date:7/29/2015)... ... July 29, 2015 , ... ... announces the launch of their 2nd generation cell therapy POD® design. The 2nd ... but it also represents a new POD® design. , “G-CON first offered ...
(Date:7/29/2015)... (PRWEB) , ... July 29, 2015 , ... ... solutions, today announced its GHS Label Guide . To align chemical container ... (GHS), this guide includes explanations of label components, an example of an accurate ...
(Date:7/29/2015)... NEW YORK , July 29, 2015 /PRNewswire/ ... neuropathology testing, announces increased partnerships with VA and ... offers Epidermal Nerve Fiber Density (ENFD) and Sweat ... of small fiber neuropathy ( https://therapath.com/skin ). ... Epidermal Nerve Fiber Density (ENFD) on punch skin ...
Breaking Biology Technology:HealthSouth Reports Results for Second Quarter 2015 2HealthSouth Reports Results for Second Quarter 2015 3HealthSouth Reports Results for Second Quarter 2015 4HealthSouth Reports Results for Second Quarter 2015 5HealthSouth Reports Results for Second Quarter 2015 6HealthSouth Reports Results for Second Quarter 2015 7HealthSouth Reports Results for Second Quarter 2015 8HealthSouth Reports Results for Second Quarter 2015 9HealthSouth Reports Results for Second Quarter 2015 10HealthSouth Reports Results for Second Quarter 2015 11HealthSouth Reports Results for Second Quarter 2015 12HealthSouth Reports Results for Second Quarter 2015 13HealthSouth Reports Results for Second Quarter 2015 14HealthSouth Reports Results for Second Quarter 2015 15HealthSouth Reports Results for Second Quarter 2015 16HealthSouth Reports Results for Second Quarter 2015 17HealthSouth Reports Results for Second Quarter 2015 18HealthSouth Reports Results for Second Quarter 2015 19HealthSouth Reports Results for Second Quarter 2015 20HealthSouth Reports Results for Second Quarter 2015 21HealthSouth Reports Results for Second Quarter 2015 22HealthSouth Reports Results for Second Quarter 2015 23HealthSouth Reports Results for Second Quarter 2015 24HealthSouth Reports Results for Second Quarter 2015 25HealthSouth Reports Results for Second Quarter 2015 26HealthSouth Reports Results for Second Quarter 2015 27HealthSouth Reports Results for Second Quarter 2015 28HealthSouth Reports Results for Second Quarter 2015 29HealthSouth Reports Results for Second Quarter 2015 30HealthSouth Reports Results for Second Quarter 2015 31HealthSouth Reports Results for Second Quarter 2015 32HealthSouth Reports Results for Second Quarter 2015 33HealthSouth Reports Results for Second Quarter 2015 34HealthSouth Reports Results for Second Quarter 2015 35HealthSouth Reports Results for Second Quarter 2015 36
... most conductive material, discovered in 2004 at the University ... Novoselov, has the potential to revolutionize material science. , ... scientists the Nobel Prize for Physics last year and ... plans for a 50m graphene research hub to be ...
... Novelda AS announced today two new antennas for its CMOS Impulse ... on a Sinuous Antenna geometry. The antenna itself consists of two ... the antenna itself; the lower PCB is a balancing network. The ... can be lowered by attaching a lens. This lens is built ...
... AlloSource, ( www.allosource.org ) a leading developer, ... use in surgical procedures around the world, is among ... Denver Business Journal,s inaugural awards program. With concerns ... employee benefits, the Denver Business Journal sought ...
Cached Biology Technology:Graphene's 'Big Mac' creates next generation of chips 2Wideband Antenna for Novelda Nanoscale Impulse Radar 2AlloSource Named One of Denver's Healthiest Employers 2AlloSource Named One of Denver's Healthiest Employers 3
Lipofectin Reagent is the reagent of choice for some cell lines; cells of endothelial derivation transfect well with Lipofectin Reagent....
... miRNA Isolation Traditional mRNA isolation procedures ... can result in the loss of substantial ... Isolation Kit purifies all RNA species (including ... an enrichment procedure included in the mirVana ...
anti-JNK2 Immunogen: Recombinant human JNK2 protein Accession Number: NM_002752 Quality Assurance: Routinely evaluated by immunoblot. Molecular Weight: 46 and/or 54 kDa Available ...
... Synthetic peptide derived from the C-terminal region ... kinase C zeta isoform (PKCzeta). Specificity: ... protein. Recognizes PKCzeta and PKMzeta (PKCzeta ... Reactivity: Mouse Rat (positive controls: mouse ...
Biology Products: