Navigation Links
New technique to see neurons of the deep brain for months at a time developed at Stanford
Date:1/16/2011

Travel just one millimeter inside the brain and you'll be stepping into the dark.

Standard light microscopes don't allow researchers to look into the interior of the living brain, where memories are formed and diseases such as dementia and cancer can take their toll.

But Stanford scientists have devised a new method that not only lets them peer deep inside the brain to examine its neurons but also allows them to continue monitoring for months.

The technique promises to improve understanding of both the normal biology and diseased states of this hidden tissue.

Other recent advances in micro-optics had enabled scientists to take a peek at cells of the deep brain, but their observations captured only a momentary snapshot of the microscopic changes that occur over months and years with aging and illness.

The Stanford development appears online Jan. 16 in the journal Nature Medicine. It also will appear in the February 2011 print edition.

Scientists study many diseases of the deep brain using mouse models, mice that have been bred or genetically engineered to have diseases similar to human afflictions.

"Researchers will now be able to study mouse models in these deep areas in a way that wasn't available before," said senior author Mark Schnitzer, associate professor of biology and of applied physics.

Because light microscopy can only penetrate the outermost layer of tissues, any region of the brain deeper than 700 microns or so (about 1/32 of an inch) cannot be reached by traditional microscopy techniques. Recent advances in micro-optics had allowed scientists to briefly peer deeper into living tissues, but it was nearly impossible to return to the same location of the brain and it was very likely that the tissue of interest would become damaged or infected.

With the new method, "Imaging is possible over a very long time without damaging the region of interest," said Juergen
'/>"/>

Contact: Louis Bergeron
louisb3@stanford.edu
650-725-1944
Stanford University
Source:Eurekalert  

Page: 1 2

Related biology news :

1. NJIT professor finds engineering technique to identify disease-causing genes
2. New technique enables assessment of drought performance
3. New technique eliminates toxic drugs in islet transplant in diabetic mice
4. These shells dont clam up: Innovative technique to record human impact on coastal waters
5. Einstein researchers develop technique to count messages made by single genes
6. These shells dont clam up: Innovative technique to record human impact on coastal waters
7. Novel technique for fluorescence tomography of tumors in living animals
8. New edition of laboratory manual includes cutting-edge techniques to study gene regulation
9. New technique is quantum leap forward in understanding proteins
10. Novel technique changes lymph node biopsy, reduces radiaiton exposure
11. Novel technique changes lymph node biopsy, reduces radiation exposure
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New technique to see neurons of the deep brain for months at a time developed at Stanford
(Date:7/25/2014)... molecular testing panel developed at UPMC greatly increases ... for patients with thyroid nodules and cancer, report ... (UPCI), partner with UPMC CancerCenter., The test, available ... diagnostic testing agencies, improved the chances of patients ... according to the study published this month in ...
(Date:7/25/2014)... July 25, 2014 Biometrics industry ... turning to digital technology for online & commerce payments ... Inc. (NASDAQ: GOOG ), LifeLock Inc. (NYSE: ... V ), Apple Inc. (NASDAQ: AAPL ) ... (OTCQB: NXTD) a biometric authentication company focused on the ...
(Date:7/24/2014)... loss leads to conflict among people around the world, ... (WCS) Health & Ecosystems: Analysis of Linkages (HEAL) Program ... to tackle global biodiversity decline. , The harvest of ... people and provides protein for more than a billion ... surprise that today,s unprecedented loss of wildlife, is bringing ...
Breaking Biology News(10 mins):Test increases odds of correct surgery for thyroid cancer patients 2Test increases odds of correct surgery for thyroid cancer patients 3Consumer Needs for Identity Theft Security Grows with Popularity of Latest Smart Technology Products - Biometrically Secure Digital Wallet to Replace Credit Card Dependency 2Consumer Needs for Identity Theft Security Grows with Popularity of Latest Smart Technology Products - Biometrically Secure Digital Wallet to Replace Credit Card Dependency 3Consumer Needs for Identity Theft Security Grows with Popularity of Latest Smart Technology Products - Biometrically Secure Digital Wallet to Replace Credit Card Dependency 4Consumer Needs for Identity Theft Security Grows with Popularity of Latest Smart Technology Products - Biometrically Secure Digital Wallet to Replace Credit Card Dependency 5Consumer Needs for Identity Theft Security Grows with Popularity of Latest Smart Technology Products - Biometrically Secure Digital Wallet to Replace Credit Card Dependency 6New study draws links between wildlife loss and social conflicts 2
... diverse, densely packed human population, head for New York,s ... people, then Southwestern Florida is your best bet. This ... Strand Preserve State Park not far from the Everglades ... a census led by Robert Lcking, collections manager and ...
... potato salad? Young adults who frequently attend religious activities ... middle age as young adults with no religious involvement, ... first longitudinal study to examine the development of obesity ... "We don,t know why frequent religious participation is associated ...
... Gentel Biosciences, a leader in proteomics tools, and Van ... today the granting of U.S. Patent 7,838,634 for a new ... on the surface of an antibody array slide. Gentel ... 2006. According to Brian H. Haab, Ph.D., head of ...
Cached Biology News:Study finds remarkable diversity of lichen species in Florida state park 2Study finds remarkable diversity of lichen species in Florida state park 3Religious young adults become obese by middle age 2Religious young adults become obese by middle age 3New technology to improve early detection and prognosis of cancer 2
(Date:7/26/2014)... 2014 Canada Endoscopy Visualization Systems ... on the Canada Endoscopy Visualization Systems market. The ... volume (in units) and average prices (in US ... Systems, Mid-Range Endoscopy Visualization Systems and Low-End Endoscopy ... http://www.marketresearchreports.biz/analysis/213254 . , The report also provides company ...
(Date:7/25/2014)... July 25, 2014 Research and ... "Global Metabolomics Market 2014-2018" report to their ... Metabolomics or Metabonomics is the scientific ... become a new experimental technique that is being ... sciences. Metabolites are small molecules that are present ...
(Date:7/25/2014)... July 25, 2014  Galmed Pharmaceuticals Ltd. (Nasdaq: ... on the development and commercialization of a once-daily, oral ... gallstones, today announced financial results for the period ended ... Summary: , Reported cash and cash equivalents totaling ... at December 31, 2013.  , Reported a net ...
(Date:7/24/2014)... -- A novel combination of microscopy and data processing ... Ridge National Laboratory an unprecedented look at the surface ... electrochemical properties. , The research team led by ... of a perovskite manganite, a complex material that exhibits ... understand surface behavior could benefit researchers who are interested ...
Breaking Biology Technology:Canada Endoscopy Visualization Systems Market Outlook to 2020: MarketResearchReports.Biz 2Canada Endoscopy Visualization Systems Market Outlook to 2020: MarketResearchReports.Biz 3Canada Endoscopy Visualization Systems Market Outlook to 2020: MarketResearchReports.Biz 4Canada Endoscopy Visualization Systems Market Outlook to 2020: MarketResearchReports.Biz 5Global Metabolomics Market 2014-2018: Key Vendors are Agilent, Bio-Rad, Bruker, Human Metabolome and Metabolon 2Galmed Pharmaceuticals Reports First Half 2014 Financial Results 2Galmed Pharmaceuticals Reports First Half 2014 Financial Results 3Galmed Pharmaceuticals Reports First Half 2014 Financial Results 4Galmed Pharmaceuticals Reports First Half 2014 Financial Results 5Galmed Pharmaceuticals Reports First Half 2014 Financial Results 6ORNL study reveals new characteristics of complex oxide surfaces 2
... - Dan Rooney knows soil. He also knows ... after starting his Madison-based company, his ideas about turning ... ,"There is information about location everywhere," said Rooney, founder ... , ,Combining that information with the growing power of ...
... Eric Schmidt, then the CTO of Sun Microsystems, gave ... language called Java. A thoroughly modern development platform for ... Java promised to ease programming headaches, the biggest of ... another. , ,Today, we can debate whether Java ...
... Wis. - Craig Schiefelbein believes in reincarnation - in ... - and still counting - reiterations of his company, ... its 20 th anniversary with a very important streak ... is a rare breed - a memory chip broker that ...
Cached Biology Technology:Global information firm reaches diverse markets 2Global information firm reaches diverse markets 3Global information firm reaches diverse markets 4Java's undeniable impact on the Web 2Java's undeniable impact on the Web 3PDS survives with technological reinvention 2PDS survives with technological reinvention 3PDS survives with technological reinvention 4PDS survives with technological reinvention 5
... PowerPac 3000 power supply is the ... for isoelectric focusing, DNA sequencing, isotachophoresis, ... western blotting, and submerged gel nucleic ... powre, the PowerPac 3000 power supply ...
... wide mini ReadySub-Cell GT cell and PowerPac basic ... electrophoresis of nucleic acids in agarose gels. The ... lid with cables and electrodes, and leveling bubble. ... V, provides output of 10-300 V, 4-400 mA, ...
... and you reduce the chance of error. ... 8000. Developed using Beckman Coulters extensive experience ... electrophoresis technology, the CEQ 8000 is a ... automatically fills the capillary array with a ...
... CZE 2000 Capillary Electrophoresis System uses ... protein electrophoresis (SPE), urine protein electrophoresis ... and accurate analysis. The system is ... preparation and no staining to process ...
Biology Products: