Navigation Links
New technique enables drug tests via exhaled breath
Date:5/19/2010

A new study from the Swedish medical university Karolinska Institutet presents a new technique that makes drug testing possible through exhaled air for the first time. By examining people who had received emergency care for an amphetamine overdose, the researchers found that in all cases there were traces of amphetamine and metamphetamine in the exhaled breath.

"Traditionally, drugs tests have been carried out using urine and blood samples," says Professor Olof Beck, who led the study. "In recent years we've been trying to find simpler alternatives using saliva, which, unfortunately, has proved difficult. Our results open the way for a new kind of drugs test, which is simple and safe to conduct and that requires no integrity-violating monitoring or medical staff."

Drug abuse is a huge social problem and drugs tests are used widely and comprehensively by the healthcare and social services, the legal system, at workplaces and schools. Reliable drugs tests are important for making correct diagnoses and for keeping tabs on drug users to ensure that they are following their prescribed treatment. Alcohol use can easily be checked in a breathalyser, and the technology is available for conducting measurements in a way that does not violate a person's integrity. Measurements of other substances in the exhaled breath are also available for diagnosing diseases such as cancer, asthma and diabetes.

In this present study, which is published in the latest issue of the Journal of Analytical Toxicology, scientists at Karolinska Institutet have developed a new and unique method for collecting narcotic substances from the exhaled breath. This they did by asking subjects to breathe into a specially designed mask for ten minutes, whereupon the exhaled air was collected and passed through a filter, which trapped the narcotic substances. These filters were then analysed using combined liquid chromatography and tandem mass-spectrometry, techniques that are highly sensitive and reliable.

The researchers took samples from 12 patients who had been admitted into emergency care with toxic symptoms after having taken amphetamines. The samples were taken after the effects of the drug had worn off and with the permission of the regional ethical review board in Stockholm. The ingestion of the drug was confirmed in the patient group through urine and blood samples. In all cases, the researchers were able to ascertain the presence of amphetamine and metamphetamine (a narcotics-classed central-stimulating substance similar to amphetamine) in the exhaled breath as well. The measured excretion rate was between 0.2 and 139 pg/min, which is very low compared to the blood and urine. No amphetamine or metamphetamine were detected in samples from healthy controls.

"The results are convincing and very promising," says Professor Beck. "The study is the first to report the possibility of measuring drugs in the exhaled breath, and represents a unique, unexpected finding. We now have to move on to other drugs that are of interest for this type of breath test, and to develop the sampling and analysis methods. An instrument like a breathalyser for drugs would be the optimal solution for the efficient control of drug use by motorists, for example."


'/>"/>

Contact: Katarina Sternudd
katarina.sternudd@ki.se
46-852-483-895
Karolinska Institutet
Source:Eurekalert

Related biology news :

1. New technique can be breakthrough for early cancer diagnosis
2. University of Leicester scientists discover technique to help friendly bacteria
3. New technique reveals subtle force-induced changes in biomolecules conformation
4. New magnetic separation technique might detect multiple pathogens at once
5. New technique captures chemical reactions in a single living cell at unprecedented resolution
6. Software Techniques Inc. Selects M2SYS Fingerprint Software to Meet Continuous Growth and Demand for Desktop Biometric Time & Attendance Solutions
7. New X-ray technique targets terrorists and tumors
8. Technique controls nanoparticle size, makes large numbers
9. New technique could dramatically lower costs of DNA sequencing
10. New techniques create butanol
11. New radar satellite technique sheds light on ocean current dynamics
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/11/2017)... 11, 2017 No two people are ... the New York University Tandon School of Engineering ... found that partial similarities between prints are common ... mobile phones and other electronic devices can be ... vulnerability lies in the fact that fingerprint-based authentication ...
(Date:4/5/2017)... April 5, 2017 Today HYPR Corp. ... the server component of the HYPR platform is officially ... the end-to-end security architecture that empowers biometric authentication across ... has already secured over 15 million users across the ... of connected home product suites and physical access represent ...
(Date:3/30/2017)... March 30, 2017  On April 6-7, 2017, Sequencing.com ... Genome hackathon at Microsoft,s headquarters in ... will focus on developing health and wellness apps that ... Hack the Genome is the first hackathon for ... world,s largest companies in the genomics, tech and health ...
Breaking Biology News(10 mins):
(Date:4/21/2017)... ... April 21, 2017 , ... Frederick Innovative ... range of emerging bio and technology start-ups, is hosting “Celebration Friday” (a festive ... event will start with libations and networking at 3:30 p.m. at FITCI’s 4539 ...
(Date:4/20/2017)... ... April 20, 2017 , ... Assured Enterprises, Inc. ... offer a full spectrum of digital security goods and services. The strategic partners ... the ground-breaking proactive cybersecurity services and products through Assured Enterprises. The two companies ...
(Date:4/20/2017)... ... April 20, 2017 , ... Husson ... clinical research community’s growing body of knowledge during its Eighth Annual Research ... and the adjacent Darling Atrium. During the event, undergraduates, graduate students, and faculty ...
(Date:4/20/2017)... MA (PRWEB) , ... April 20, 2017 , ... ... brightness light sources for advanced technology applications, announced today that Chief Executive Officer ... (NAAB). , SEMI is the global industry association connecting the electronics ...
Breaking Biology Technology: