New technique determines the number of fat cells remains constant in all ...(of fat cells two years after the surgery...)

Date:5/9/2008

of fat cells two years after the surgery. Similarly, significant weight gain (15-25 percent) over several months in non-obese adult men resulted in significant increase in body fat volume but no change in number. Subsequent weight loss back to baseline resulted in a decrease in fat cell volume but no change in the number of fat cells.

If you are overweight and you lose weight, you still have the capacity to store lipids because you still have the same number of fat cells. That may be why it's so hard to keep the weight off, Buchholz said.

Overweight and obesity result from an energy imbalance - eating too many calories and not getting enough physical activity. Body weight is the result of genes, metabolism, behavior, environment, culture and socioeconomic status. This work may give us new ideas of how to deal with the diseases that go along with obesity, Buchholz said.

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Contact: Anne Stark stark8@llnl.gov 925-422-9799 DOE/Lawrence Livermore National Laboratory Source:Eurekalert

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