Navigation Links
New technique can be breakthrough for early cancer diagnosis
Date:9/12/2007

Early detection of disease is often critical to how successful treatment can be. Therefore, the development of new methods of diagnosis is a hot research field, where every small step is of great importance. In an article in the latest issue of Molecular & Cellular Proteomics, Uppsala University researchers describe a technique that the journal regards as especially interesting.

Proteins build up the bodys cells and tissues, and our knowledge of the human genome also entails that todays scientists are aware of all of the proteins that our body can produce. It is known that many morbid conditions can be linked to changes in proteins, so it is important to enhance our knowledge of what proteins bind to each other, how they work together, and how processes are impacted by various disturbances.

In 2006 Ola Sderberg and his colleagues at the Department of Genetics and Pathology devised a new technique, in situ PLA (in situ proximity ligation assay), that could detect communication between proteins in cells. These researchers have now refined the method and can now see how proteins undergo change inside a cell.

The method provides a better potential to truly understand how proteins function in the cell and can show what is wrong with a sick cell, as in cancer, for instance. The refined method has the potential to revolutionize cancer diagnostics, so there has been a great deal of interest in the method from the research community, says Ola Sderberg.

The technique is more sensitive and more reliable than other available techniques in molecular diagnostics, and it has already started to be sold by the Uppsala company Olink, so there are high hopes that it will soon be used in health care.


'/>"/>

Contact: Anneli Waara
anneli.waara@uadm.uu.se
46-184-711-974
Uppsala University
Source:Eurekalert

Page: 1

Related biology news :

1. New Technique for Tracking Gene Regulators
2. Live Recombinant Adenovirus Vaccine Technique Explored
3. New lab technique identifies high levels of pathogens in therapy pool
4. Brain-mapping technique aids understanding of sleep, wakefulness
5. Technique may allow cancer patients to freeze eggs, preserving fertility before starting treatment
6. Study reveals new technique for fingerprinting environmental samples
7. Researchers Find New Technique To Identify Fetal Genetic Material From Amniotic Fluid
8. Researchers pioneer new gene therapy technique using natural repair process
9. Newer imaging techniques may lead to over-treatment
10. Gene silencing technique offers new strategy for treating, curing disease
11. Mosaic mouse technique offers a powerful new tool to study diseases and genetics
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/22/2014)... DUBLIN , Dec. 22, 2014 /PRNewswire/ ... ) has announced the addition of the ... report to their offering. ... This insight provides an overview of the ... Watermarking aims to control and monitor piracy ...
(Date:12/19/2014)... , Dec. 18, 2014  23andMe, Inc., the ... a study that pinpoints fine-scale differences in genetic ancestry ... . Since immigrants first arrived more ... States has served as a meeting place ... American history and the ongoing mixing of peoples with ...
(Date:12/17/2014)... , Dec. 15, 2014  HITLAB SM ... Practices (GCP) audit to confirm its adherence to ... This accomplishment enables HITLAB to conduct regulated smart ... highest principles for patient safety and research quality. ... healthcare access, quality, and delivery with innovative technology," ...
Breaking Biology News(10 mins):The Global Watermarking and Fingerprinting Markets 223andMe Study Sketches Genetic Portrait of the United States 223andMe Study Sketches Genetic Portrait of the United States 323andMe Study Sketches Genetic Portrait of the United States 4HITLAB Completes GCP Audit for FDA Smart Device & App Compliance 2
... Nearctic deposited in the United States National Museum of ... Collection of Insects, researchers have found 16 new species ... seven new species. The new species are described ... Species, and a Key of the Charipinae (Hymenoptera: Cynipoidea: ...
... nucleus. In this state it synthesises proteins and, even though ... fact its structure is governed by precise rules that are ... studied DNA by observing it experimentally with a variety of ... silico, that is to say, the study of DNA by ...
... century writer Adam Smith provided a workable metaphor for the ... of Nations," he argued that even as individuals strive, through ... contribute---as if under the influence of a "hidden hand"---to an ... physicist and alive in the 21st century he might be ...
Cached Biology News:25 years of DNA on the computer 2The entropy of nations 2The entropy of nations 3The entropy of nations 4
(Date:12/22/2014)... Dec. 22, 2014  ( www.competitivehealth.com ) — Competitive ... medical bill review and advocacy service, has signed an ... WellCard Savings discount health services marketplace. 63% ... more than they expected to pay. As part of ... costs, WellCard Savings is pleased to offer medical bill ...
(Date:12/22/2014)... 22, 2014 Fertility Associates of Memphis ... Bank USA , a network of more than 20 ... partnership, patients have fast access to a national pool ... IVF . Fertility Associates of Memphis is the only ... treatment option. , Dr. William Kutteh , director ...
(Date:12/19/2014)... BioPlus Specialty Pharmacy (BioPlus), one ... of Nick Maroulis, Pharm.D. to the newly created position ... In this position, Dr. Maroulis will continue to manage ... of our multi-site pharmacies as the company expands. Dr. ... that time he has served in many different capacities ...
(Date:12/19/2014)... Dec. 19, 2014 Bina Technologies, Inc. (Bina, ... that they have been acquired by Roche (SIX: RO, ... privately held company that provides a big data platform ... (NGS) data for the academic and translational research markets. ... and will continue to focus on development of their ...
Breaking Biology Technology:WellCard Savings Announces CoPatient Medical Bill Review Service for Members 2Fertility Associates of Memphis Announces Partnership with Donor Egg Bank USA 2Fertility Associates of Memphis Announces Partnership with Donor Egg Bank USA 3BioPlus Specialty Pharmacy Promotes Dr. Nick Maroulis to Vice President of Specialty Pharmacy Services 2Bina Technologies is acquired by Roche. 2Bina Technologies is acquired by Roche. 3
... two years of the Governor's Business Plan Contest , the ... edge of its respective industry. This year's field of 27 finalists ... by start ups like Mithridion, Inc., the 2005 winner, and ... , ,As is the custom, the winner will be announced on ...
... , Wis. - Ralph Kauten is taking direct aim ... just passed an early test. , ,Kauten, CEO of ... initial screening of its PreserveX Polymeric Micelles, a core product. ... that enter the body and is used to determine whether ...
... Madison, Wis. - As part of its $6 ... $400 million to extend coverage to customers in Wisconsin and ... continues from 2005, when Cingular invested more $300 million in ... between Illinois and Wisconsin. , ,Since the start of 2006, ...
Cached Biology Technology:Business plan finalists offer peek into entrepreneurial future 2Business plan finalists offer peek into entrepreneurial future 3Business plan finalists offer peek into entrepreneurial future 4QBI's PreserveX product passes initial test 2QBI's PreserveX product passes initial test 3
... Large (Klenow) Fragment, Exonuclease Minus, is a ... 5´→3´ and the 3´→5´ exonuclease activities present ... (1,2). It is used for random primer ... (5). Klenow Fragment, Exonuclease Minus, will leave ...
... 8-iso PGE2 is one of several isoprostanes ... is a potent renal vasoconstrictor in the rat. ... with IC50 values of 0.5 and 5 µM, ... the rat at a concentration of 4 mg/kg/min, ...
DNA Polymerase I Large (Klenow) Fragment is a DNA polymerase that lacks the 5'Cut Site3' exodeoxyribonuclease activity of intact DNA Polymerase I but it contains the 3'Cut Site5' exodeoxyribonuclease...
... offers both high-speed and high-volume versatility ... rotor options, making it ideal for a ... Versatility , High-speed (up to 15,000 ... high-volume (4 x 250mL) swinging bucket rotors ...
Biology Products: