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New system developed for early diagnosis of Alzheimer's disease
Date:6/10/2010

PET tomographies from three different databases. The first database contains 97 de-identified SPECT images which were labeled by experts and provided by Dr. Manuel Gmez-Ro and the Department of Nuclear Medicine, university hospital Virgen de las Nieves, Granada, Spain. The second database contains 60 PET images provided by the company PET- Cartuja (Seville). The third was the largest database, and it had 219 PET images provided by ADNI (United States).

These databases included brain CT scans from aged patients suffering from Alzheimer's disease or with normal development patterns. A series of algorithms were developed, which allowed the identification of brain areas affected by the disease, and helped in distinguishing diseased patients from healthy ones.

The three methods presented in this study attained 90% success rate in identifying Alzheimer through CT both PET and SPECT. At present, a computer software is being developed jointly with the company PTEC (Malaga) to translate these results into a software that can be used in hospitals. Thus, neurologists will have a tool as precise as a team of experts.

These results were partially published in the journals Information Sciences (2010), Neuroscience Letters (2009) and Electronics Letters (2009).


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Contact: Ignacio Alvarez Illan
illan@ugr.es
34-958-240-459
University of Granada
Source:Eurekalert

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