Navigation Links
New system developed for early diagnosis of Alzheimer's disease
Date:6/10/2010

This release is available in Spanish.

Researchers of the University of Granada have developed a new computer program that allows early diagnosis of Alzheimer's disease through processed images. This new system has enhanced successful early diagnosis of Alzheimer's disease up to 90%, which is an important progress within this area of study.

The study was conducted by professor Ignacio Alvarez Illn, a member of SIPBA (Signal Processing and Biomedical Applications) TIC-010 of the University of Granada, and supervised by professors Juan Manuel Grriz Sez, Javier Ramrez Prez de Inestrosa and Carlos Garca Puntonet.

Scientists of the University of Granada have validated some new techniques for diagnosing Alzheimer's disease through a series of processed images. These techniques were successfully tested, and promising results were obtained. This study is part of a wider project still under development which purpose is developing a complete software for clinical use in hospitals. It is being developed in cooperation with the companies PET-Cartuja and PTEC, and it belongs to the prizewinning project PETRI-DENCLASES, which was rewarded at the III Premios Andaluca Sociedad de la Informacin 2010 edition, a prize awarded by the Andalusian Regional Government to companies contributing to an enhanced information society.

The research group has cooperated with the international project ADNI (Alzheimer's Disease NeuroImaging Initiative), which confers an international character to the study, and has enabled the use of one of the largest database in the world concerning Alzheimer's disease.

Tomograms

To test this new automated computer-assisted diagnosis, the researchers of the University of Granada used SPECT and PET tomographies from three different databases. The first database contains 97 de-identified SPECT images which were labeled by experts and provided by Dr. Manuel Gmez-Ro and the Department of Nuclear Medicine, university hospital Virgen de las Nieves, Granada, Spain. The second database contains 60 PET images provided by the company PET- Cartuja (Seville). The third was the largest database, and it had 219 PET images provided by ADNI (United States).

These databases included brain CT scans from aged patients suffering from Alzheimer's disease or with normal development patterns. A series of algorithms were developed, which allowed the identification of brain areas affected by the disease, and helped in distinguishing diseased patients from healthy ones.

The three methods presented in this study attained 90% success rate in identifying Alzheimer through CT both PET and SPECT. At present, a computer software is being developed jointly with the company PTEC (Malaga) to translate these results into a software that can be used in hospitals. Thus, neurologists will have a tool as precise as a team of experts.

These results were partially published in the journals Information Sciences (2010), Neuroscience Letters (2009) and Electronics Letters (2009).


'/>"/>

Contact: Ignacio Alvarez Illan
illan@ugr.es
34-958-240-459
University of Granada
Source:Eurekalert

Related biology news :

1. Bursts of waves drive immune system soldiers toward invaders
2. Bioengineers at University of Pennsylvania devise nanoscale system to measure cellular forces
3. Obesity and the central nervous system -- the state of the art
4. How the plant immune system can drive the formation of new species
5. Upgraded IMG 2.3 Data Management System released by DOE JGI to eager user community
6. Systems Biology poised to revolutionize the understanding of cell function and disease
7. Europe needs collective effort on System Biology, says ESF Task Force
8. Cogent Systems and Northrop Grumman Reach Agreement to Settle Automated Fingerprint Identification Technology Suit and Create Strategic Alliance
9. Radiant Systems Selects BIO-key(R) Biometric Software for POS Solution
10. Fujitsu and HT Systems Partner to Provide Biometric Patient Identity Management
11. Fujitsu and HT Systems Partner to Provide Biometric Patient Identity Management
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/5/2017)... Allen Institute for Cell Science today announces the launch ... dynamic digital window into the human cell. The website ... deep learning to create predictive models of cell organization, ... suite of powerful tools. The Allen Cell Explorer will ... resources created and shared by the Allen Institute for ...
(Date:4/5/2017)... , April 4, 2017 KEY FINDINGS ... to expand at a CAGR of 25.76% during the ... is the primary factor for the growth of the ... https://www.reportbuyer.com/product/4807905/ MARKET INSIGHTS The global stem ... technology, application, and geography. The stem cell market of ...
(Date:4/3/2017)... 2017  Data captured by IsoCode, IsoPlexis ... a statistically significant association between the potency ... and objective response of cancer patients post-treatment. ... whether cancer patients will respond to CAR-T ... as to improve both pre-infusion potency testing and ...
Breaking Biology News(10 mins):
(Date:10/10/2017)... (PRWEB) , ... October 10, 2017 , ... ... Science Center’s FirstHand program has won a US2020 STEM Mentoring Award. Representatives of ... award for Excellence in Volunteer Experience from US2020. , US2020’s mission is to ...
(Date:10/10/2017)... ... October 10, 2017 , ... The Pittcon Program Committee is ... honoring scientists who have made outstanding contributions to analytical chemistry and applied spectroscopy. ... world’s leading conference and exposition for laboratory science, which will be held February ...
(Date:10/9/2017)... ... October 09, 2017 , ... ... October 5, 2017, in the medical journal, Epilepsia, Brain Sentinel’s SPEAC® System ... standard, video EEG, in detecting generalized tonic-clonic seizures (GTCS) using surface electromyography ...
(Date:10/6/2017)... ... October 06, 2017 , ... On ... and webinar on INSIGhT, the first-ever adaptive clinical trial for glioblastoma (GBM). The ... The event is free and open to the public, but registration is required. ...
Breaking Biology Technology: