Navigation Links
New study ushers in spring-time for slow inactivation
Date:11/17/2009

The December 2009 issue of the Journal of General Physiology (JGP) contains a paper by Christopher Ahern (The University of British Columbia, Vancouver) and colleagues that explores pore mutation effects in Shaker and other K+ channels using in vivo nonsense suppression technology. The study will be published online November 16 (www.jgp.org).

According to Riccardo Olcese (UCLA) in a commentary accompanying the manuscript, the new research elegantly addresses the relation between pore structure and slow inactivation in a non-invasive way, and the results are fascinating. Ahern and colleagues find that tetraethylammonium (TEA) accelerates slow inactivation in the Shaker mutant T449F, as if the inactivation gate were pulled closed by the presence of the TEA, a process the authors describe as "spring-in-the-door." The study sheds light on intriguing aspects of potassium pore dynamics and serves as an important foundation for subsequent research.


'/>"/>

Contact: Rita Sullivan
rsullivan@rockefeller.edu
212-327-8603
Rockefeller University Press
Source:Eurekalert

Page: 1

Related biology news :

1. DoseCue(TM) Presents Positive Study Results at BioTech 2009
2. Study shows link between influenza virus and fever
3. Study pits man v. machine in piecing together 425-million-year-old jigsaw
4. New study links vitamin D deficiency to cardiovascular disease and death
5. Largest gene study of childhood IBD identifies 5 new genes
6. Exploration by explosion: Studying the inner realm of living cells
7. Carnegie Mellon researchers to develop probes to study cellular GPS
8. CSHL study shows that some malignant tumors can be shut down after all
9. USC study finds big air pollution impacts on local communities
10. Singapore scientists join international study of 10,000 vertebrates genomes
11. Study points to new uses, unexpected side effects of already existing drugs
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/30/2017)... 2017  On April 6-7, 2017, Sequencing.com will host ... hackathon at Microsoft,s headquarters in Redmond, ... on developing health and wellness apps that provide a ... Genome is the first hackathon for personal genomics ... companies in the genomics, tech and health industries are ...
(Date:3/29/2017)... , March 29, 2017  higi, the health ... in North America , today announced ... and the acquisition of EveryMove. The new investment and ... set of tools to transform population health activities through ... lifestyle data. higi collects and secures data ...
(Date:3/24/2017)... MILAN , March 24, 2017 The Controller ... Deputy Controller Mr. Abdulla Algeen have received the prestigious international ... Continue Reading ... ... small picture) and Deputy Controller Abdulla Algeen (small picture on the right) ...
Breaking Biology News(10 mins):
(Date:5/23/2017)... (PRWEB) , ... May 23, ... ... offer an unlimited source of human cardiovascular cells for research and the ... methods makes it possible to generate large numbers of cardiomyocytes (hPSC-CMs). Due ...
(Date:5/23/2017)... ... 2017 , ... Energetiq Technology, a world leader in high ... accommodate its rapid growth. , The renovations at the company’s headquarters in Woburn, ... areas. The expansion includes, a state-of-the-art engineering facility, and a second clean manufacturing ...
(Date:5/22/2017)... ... ... Stratevi, a boutique firm that partners with healthcare companies to creatively develop and ... downtown Boston at 745 Atlantic Ave. , “We are seeing that even the ... value they provide, not just to patients, but also payers. Having a presence in ...
(Date:5/19/2017)... ... , ... In response to the strong base of evidence supporting the use ... release of their Gait Trainer 3 with an Integrated Music Therapy option. This is ... in rehabilitating individuals with cerebral palsy, traumatic brain injury, stroke and Parkinson’s disease. ...
Breaking Biology Technology: