Navigation Links
New study ushers in spring-time for slow inactivation
Date:11/17/2009

The December 2009 issue of the Journal of General Physiology (JGP) contains a paper by Christopher Ahern (The University of British Columbia, Vancouver) and colleagues that explores pore mutation effects in Shaker and other K+ channels using in vivo nonsense suppression technology. The study will be published online November 16 (www.jgp.org).

According to Riccardo Olcese (UCLA) in a commentary accompanying the manuscript, the new research elegantly addresses the relation between pore structure and slow inactivation in a non-invasive way, and the results are fascinating. Ahern and colleagues find that tetraethylammonium (TEA) accelerates slow inactivation in the Shaker mutant T449F, as if the inactivation gate were pulled closed by the presence of the TEA, a process the authors describe as "spring-in-the-door." The study sheds light on intriguing aspects of potassium pore dynamics and serves as an important foundation for subsequent research.


'/>"/>

Contact: Rita Sullivan
rsullivan@rockefeller.edu
212-327-8603
Rockefeller University Press
Source:Eurekalert

Page: 1

Related biology news :

1. DoseCue(TM) Presents Positive Study Results at BioTech 2009
2. Study shows link between influenza virus and fever
3. Study pits man v. machine in piecing together 425-million-year-old jigsaw
4. New study links vitamin D deficiency to cardiovascular disease and death
5. Largest gene study of childhood IBD identifies 5 new genes
6. Exploration by explosion: Studying the inner realm of living cells
7. Carnegie Mellon researchers to develop probes to study cellular GPS
8. CSHL study shows that some malignant tumors can be shut down after all
9. USC study finds big air pollution impacts on local communities
10. Singapore scientists join international study of 10,000 vertebrates genomes
11. Study points to new uses, unexpected side effects of already existing drugs
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/16/2014)... tract infections and worldwide claims the lives of ... Ghent University have succeeded in developing a promising ... , Xavier Saelens (VIB/UGent): "We discovered a ... the development of a novel approach to vaccination ... numerous small children and elderly people." , ...
(Date:10/15/2014)... ,Models of Life, is a non-traditional biophysics textbook and ... book is a journey of discovery into biological systems ... and biological regulation. It is about how our genes ... between the billions of cells in an organism. It ... between principles, which can be found on both large ...
(Date:10/15/2014)... awarded the 44th Rosenstiel Award for Distinguished Work in ... exploring the mechanisms of genomic instability and its implications ... the second alumnus to win the Rosenstiel Award; the ... , Alt is the Charles A. Janeway Professor of ... and an investigator at the Howard Hughes Medical Institute ...
Breaking Biology News(10 mins):New perspectives for development of an RSV vaccine 2New book about life as seen from physics 2Brandeis awards 44th Rosenstiel Award to pioneering geneticist Fred Alt 2
... team led by two Texas A&M University anthropologists now ... to 2,000 years earlier than the 13,500 years ago ... The teams findings are outlined in a review article ... Modern Humans in the Americas, which synthesizes new data ...
... solar cells can be found in dye-sensitised solar cells. This ... energy by, for instance, plants and light-sensitive bacteria. Annemarie Huijser ... of solar cell, which is similar to Grtzel cells. Huijser ... on Tuesday 25 March. The use of solar cells ...
... . , OTTAWA The Government of ... of chemicals that can be used to make explosives. ... the Honourable Stockwell Day, Minister of Public Safety, today ... explosives precursors, will be implemented under the Explosives Act. ...
Cached Biology News:Substantial improvement in essential cheap solar cell process 2New regulations tighten controls on restricted chemicals 2
(Date:10/22/2014)... October 21, 2014 The North American ... market North America with analysis and forecast of revenue. ... and is expected to reach $623.6 million by 2018, ... , Browse through the TOC of the North American ... the in-depth analysis provided. This also provides a glimpse ...
(Date:10/22/2014)... Diego, CA (PRWEB) October 22, 2014 ... balances from Sartorius, A & D Weighing, Rice ... Sartorius CPA Semi-Micro Balance . The Sartorius CPA ... for an affordable high-quality, precise, and user-friendly laboratory ... manufacturing of laboratory equipment, their laboratory balances are ...
(Date:10/22/2014)... --  Synthetic Biologics, Inc. (NYSE MKT: SYN), a ... and diseases, announced today that the U.S. Patent and ... a composition of matter patent application that covers the ... This is Synthetic Biologics, first allowed patent application directly ... the Company,s extensive C. difficile patent estate. ...
(Date:10/22/2014)... HONG KONG , Oct. 22, 2014 ... enterprise, announced today that rare disease expert John ... president, research. Dr. McKew brings more than two decades ... at the National Institutes of Health, Wyeth Research and ... McKew will lead aTyr,s efforts to expand and translate ...
Breaking Biology Technology:The North American crystal oscillator market is expected to reach $623.6 million by 2018 - New Report by MicroMarket Monitor 2The North American crystal oscillator market is expected to reach $623.6 million by 2018 - New Report by MicroMarket Monitor 3The North American crystal oscillator market is expected to reach $623.6 million by 2018 - New Report by MicroMarket Monitor 4Pipette.com Launches the Addition of Sartorius CPA Semi-Micro Balance to Their Product Portfolio with Special Promotional Pricing 2Pipette.com Launches the Addition of Sartorius CPA Semi-Micro Balance to Their Product Portfolio with Special Promotional Pricing 3Synthetic Biologics Announces Allowance of Key U.S. Composition of Matter Patent for C. difficile Program 2Synthetic Biologics Announces Allowance of Key U.S. Composition of Matter Patent for C. difficile Program 3Synthetic Biologics Announces Allowance of Key U.S. Composition of Matter Patent for C. difficile Program 4aTyr Pharma Appoints John C. McKew, Ph.D., as Vice President, Research 2aTyr Pharma Appoints John C. McKew, Ph.D., as Vice President, Research 3
... from finely etched lines in silicon wafers to ... of Energy,s Lawrence Berkeley National Laboratory (Berkeley Lab) ... through a molecular junctiona nanometer scale circuit element ... Their findings reveal the electrical resistance through this ...
... ONTY ) (TSX:ONY), a biotechnology company specializing ... treatment of cancer, today announced that it intends to ... results on Monday, March 9, 2009 after the close ... Oncothyreon,s management expects to discuss these financial results and ...
... an unknown organism often calls for total shutdown ... be identified and eliminated. Such shutdowns can ... of medical device and pharmaceutical manufacturers alike.A new ... DNA Sequencing Services Help Prevent Catastrophic Cleanroom Shutdowns ...
Cached Biology Technology:Researchers discover a potential on-off switch for nanoelectronics 2Researchers discover a potential on-off switch for nanoelectronics 3Researchers discover a potential on-off switch for nanoelectronics 4White Paper Details How DNA Sequencing Services Can Prevent Cleanroom Shutdowns at Medical Device and Pharmaceutical Manufacturers 2White Paper Details How DNA Sequencing Services Can Prevent Cleanroom Shutdowns at Medical Device and Pharmaceutical Manufacturers 3
Rabbit polyclonal to BCA1 ( Abpromise for all tested applications). Antigen: Generated using E.coli expressed mouse BCA1. Entrez GeneID: 10563 SWISS Protein ID: O43927...
PKC Sampler Kit 10 mu g each...
Purified anti-SOCS3...
AMAP Multi Site-directed Mutagenesis Kit Research Focus: other Storage Temperature: -20C Shipping Temperature: dry ice...
Biology Products: