Navigation Links
New study ushers in spring-time for slow inactivation
Date:11/17/2009

The December 2009 issue of the Journal of General Physiology (JGP) contains a paper by Christopher Ahern (The University of British Columbia, Vancouver) and colleagues that explores pore mutation effects in Shaker and other K+ channels using in vivo nonsense suppression technology. The study will be published online November 16 (www.jgp.org).

According to Riccardo Olcese (UCLA) in a commentary accompanying the manuscript, the new research elegantly addresses the relation between pore structure and slow inactivation in a non-invasive way, and the results are fascinating. Ahern and colleagues find that tetraethylammonium (TEA) accelerates slow inactivation in the Shaker mutant T449F, as if the inactivation gate were pulled closed by the presence of the TEA, a process the authors describe as "spring-in-the-door." The study sheds light on intriguing aspects of potassium pore dynamics and serves as an important foundation for subsequent research.


'/>"/>

Contact: Rita Sullivan
rsullivan@rockefeller.edu
212-327-8603
Rockefeller University Press
Source:Eurekalert

Page: 1

Related biology news :

1. DoseCue(TM) Presents Positive Study Results at BioTech 2009
2. Study shows link between influenza virus and fever
3. Study pits man v. machine in piecing together 425-million-year-old jigsaw
4. New study links vitamin D deficiency to cardiovascular disease and death
5. Largest gene study of childhood IBD identifies 5 new genes
6. Exploration by explosion: Studying the inner realm of living cells
7. Carnegie Mellon researchers to develop probes to study cellular GPS
8. CSHL study shows that some malignant tumors can be shut down after all
9. USC study finds big air pollution impacts on local communities
10. Singapore scientists join international study of 10,000 vertebrates genomes
11. Study points to new uses, unexpected side effects of already existing drugs
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/9/2016)... Finland , June 9, 2016 ... National Police deploy Teleste,s video security solution to ensure the ... France during the major tournament ... data communications systems and services, announced today that its video ... Prefecture to back up public safety across the ...
(Date:6/3/2016)... June 3, 2016 ... Nepal hat ein ... hochsicherer geprägter Kennzeichen, einschließlich Personalisierung, Registrierung und ... der Produktion und Implementierung von Identitätsmanagementlösungen. Zahlreiche ... im Januar teilgenommen, aber Decatur wurde als ...
(Date:6/2/2016)...   The Weather Company , an IBM Business (NYSE: ... capability in which consumers will be able to interact with ... via voice or text and receive relevant information about the ... Marketers have long sought an advertising solution that can create ... relevant and valuable; and can scale across millions of interactions ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... Prostate Cancer Foundation (PCF) is pleased to announce 24 new Young ... cancer. Members of the Class of 2016 were selected from a pool of ... More About the Class of 2016 PCF Young Investigators ... ... ...
(Date:6/23/2016)... ... June 23, 2016 , ... ... the launch of the Supplyframe Design Lab . Located in Pasadena, Calif., ... the future of how hardware projects are designed, built and brought to market. ...
(Date:6/23/2016)... , June 23, 2016 Apellis ... Phase 1 clinical trials of its complement C3 ... single and multiple ascending dose studies designed to ... (PD) of subcutaneous injection in healthy adult volunteers. ... (SC) either as a single dose (ranging from ...
(Date:6/23/2016)... NEW YORK , June 23, 2016 ... the trading session at 4,833.32, down 0.22%; the Dow Jones ... the S&P 500 closed at 2,085.45, down 0.17%. Stock-Callers.com has ... INFI ), Nektar Therapeutics (NASDAQ: NKTR ... BIND Therapeutics Inc. (NASDAQ: BIND ). Learn more ...
Breaking Biology Technology: