Navigation Links
New study shows how copper restricts the spread of global antibiotic-resistant infections
Date:12/4/2012

New research from the University of Southampton has shown that copper can prevent horizontal transmission of genes, which has contributed to the increasing number of antibiotic-resistant infections worldwide.

Horizontal gene transfer (HGT) in bacteria is largely responsible for the development of antibiotic-resistance, which has led to an increasing number of difficult-to-treat healthcare-associated infections (HCAIs).

The newly-published paper, which appears in the journal mBio, shows that while HGT can take place in the environment, on frequently-touched surfaces, such as door handles, trolleys and tables, which are made from stainless steel copper prevents this process from occurring and rapidly kills bacteria on contact.

Lead author Professor Bill Keevil, Chair in Environmental Healthcare at the University of Southampton, explains: "Whilst studies have focussed on HGT in vivo (an experiment that is done in the body of a living organism), this work investigates whether the ability of pathogens to persist in the environment, particularly on touch surfaces, may also play an important role. Here we show prolonged survival of multidrug resistant Escherichia coli and Klebsiella pneumoniae on stainless steel surfaces for several weeks. However, rapid death of both antibiotic-resistant strains and destruction of plasmid and genomic DNA was observed on copper and copper alloy surfaces, which could be useful in the prevention of infection spread and gene transfer."

Showing that horizontal transmission of genes (for example, those governing antibiotic resistance) occurs on touch surfaces, supports the important role of the environment in infection prevention.

Professor Keevil summarises: "We know many human pathogens survive for long periods in the hospital environment and can lead to infection, expensive treatment, blocked beds and death. What we have shown in this work is the potential for strategically-placed antimicrobial copper touch surfaces to not only break the chain of contamination, but also actively reduce the risk of antibiotic resistance developing at the same time. Provided adequate cleaning continues in critical environments, copper can be employed as an important additional tool in the fight against pathogens."

Beyond the healthcare environment, copper also has a wider role to play in infection control. Professor Keevil explains: "Copper touch surfaces have promise for preventing antibiotic resistance transfer in public buildings and mass transportation systems, which lead to local and in the case of jet travel rapid worldwide dissemination of multi-drug resistant superbugs as soon as they appear.

"People with inadequate hand hygiene could exchange their bugs and different antibiotic resistance genes just by touching a stair rail or door handle, ready to be picked up by someone else and passed on. Copper substantially reduces and restricts the spread of these infections, making an important contribution to improved hygiene and, consequently, health."

Installations of copper touch surfaces have already taken place across the UK and around the world, harnessing copper's ability to continuously reduce bioburden and consequently the risk of HCAI transmission. This research offers additional evidence to deploy copper (and copper-containing alloys that benefit from the metal's antimicrobial properties) in the form of touch surfaces to provide extra protection alongside standard hygiene practices.


'/>"/>
Contact: Glenn Harris
G.Harris@soton.ac.uk
44-023-805-93212
University of Southampton
Source:Eurekalert  

Related biology news :

1. Study by UC Santa Barbara researchers suggests that bacteria communicate by touch
2. Law that regulates shark fishery is too liberal: UBC study
3. New study will help protect vulnerable birds from impacts of climate change
4. Study jointly led by UCSB researcher supports theory of extraterrestrial impact
5. BYU study: Using a gun in bear encounters doesnt make you safer
6. 15-year study: When it comes to creating wetlands, Mother Nature is in charge
7. Pycnogenol (French maritime pine bark extract) shown to improve menopause symptoms in new study
8. Crystal structure of archael chromatin clarified in new study
9. EU-funded study underlines importance of Congo Basin for global climate and biodiversity
10. University of Houston study shows BP oil spill hurt marshes, but recovery possible
11. Study demonstrates cells can acquire new functions through transcriptional regulatory network
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New study shows how copper restricts the spread of global antibiotic-resistant infections
(Date:3/9/2017)... Australia , March 9, 2017 4Dx ... prestigious World Lung Imaging Workshop at the University of ... was invited to deliver the latest data to world ... recognised event brings together leaders at the forefront of ... in lung imaging. "The quality of ...
(Date:3/7/2017)... CITY , March 7, 2017   HireVue ... help top global companies identify the best talent, faster, ... as Chief Sales Officer (CSO) and Diana Kucer ... appointments round out a seasoned executive team poised to drive ... beyond, building on a year of record bookings in ...
(Date:3/2/2017)... Summary This report provides all the information ... partnering interests and activities since 2010. Download the ... Deals and Alliance since 2010 report provides an in-depth ... world,s leading life sciences companies. On demand ... of the most up to date deal and company ...
Breaking Biology News(10 mins):
(Date:3/24/2017)... , March 24, 2017 ... the trading session at 5,817.69, down 0.07%; the Dow ... 20,656.58; and the S&P 500 closed at 2,345.96, marginally ... 4 sectors closed in green, 4 sectors finished in ... This Friday, Stock-Callers.com has initiated reports coverage on the ...
(Date:3/23/2017)... -- Research and Markets has announced the addition ... their offering. ... The Global Market for Bioproducts Should Reach $714.6 ... CAGR of 8.9%, This research report quantifies ... major product segments: bio-derived chemicals, biofuels, pharmaceuticals (biodrugs and herbal/botanicals), ...
(Date:3/23/2017)... ... March 23, 2017 , ... ... selected by the Connecticut Technology Council (CTC) as a 2017 Women of Innovation® ... annual Women of Innovation Awards Dinner. , The dinner recognizes women accomplished in ...
(Date:3/23/2017)... , March 23, 2017 In ... four equities in the Biotech industry: Sangamo Therapeutics Inc. ... Inc. (NYSE MKT: SYN), and Regulus Therapeutics Inc. (NASDAQ: ... , 2017, Credit Suisse upgraded its rating on Pharmaceuticals/Biotechnology to "Overweight" from ... their free report at: ...
Breaking Biology Technology: