Navigation Links
New study indicates smallpox vaccination effective for decades
Date:11/30/2008

New York, December 1, 2008 Although naturally occurring smallpox was eradicated in 1977, there is concern that bioterrorists might obtain smallpox from a laboratory and release it into the population. Under such circumstances, the supply of smallpox vaccine may be insufficient for universal administration. In a study published in the December 2008 issue of The American Journal of Medicine, researchers found that lifetime protection is obtained from just one vaccination, even when that vaccination occurred as much as 88 years ago. They conclude that in the event of a smallpox bioterrorist attack, vaccinia smallpox vaccine should be used first on individuals who have not been vaccinated previously.

Examining 246 participants of the Baltimore Longitudinal Study of Aging, investigators from the National Institute on Aging and the National Institute of Allergy and Infectious Diseases, National Institutes of Health found permanent immunity was conferred by vaccination or by survival from an active smallpox infection. In the sample, 209 subjects were vaccinated one or more times 13 to 88 years prior to the study; an additional 18 had had childhood smallpox, and 29 with no history of vaccination or smallpox were included.

Although the vaccinia virus vaccine was used since the late 18th century, routine vaccination was discontinued more than 30 years ago in many countries. Most Americans under 35 have never been vaccinated and most over 35 have not received booster immunizations since the early 1970s. If a bioterrorist attack were to occur, it would be critical to know who already had effective immunity and would not need to be vaccinated, leaving another dose available for someone else.

Current recommendations relating to smallpox vaccination has been that people with repeated exposure to smallpox, for example travelers to endemic areas, should be revaccinated every five years. This study suggests that such reimmunizations may not be
'/>"/>

Contact: Pamela Poppalardo
ajmmedia@elsevier.com
212-633-3944
Elsevier Health Sciences
Source:Eurekalert

1

GOOD

Page: 1 2

Related biology news :

1. Study identifies genetic variants giving rise to differences in metabolism
2. UNC expands brain imaging study of infants at risk for autism
3. Shrimp trawling may boost mercury in red snapper, study suggests
4. Dolphin population stunted by fishing activities, Scripps/NOAA study finds
5. Nature Medicine study shows Peregrines bavituximab can cure lethal virus infections
6. Hairspray is linked to common genital birth defect, says study
7. Carbon dioxide already in danger zone, warns study
8. Duke study pinpoints potential green collar job growth in US
9. UNC, Yale partner to study effects of cocaine use on mother-infant relationships
10. Montana State researchers receive grant to study algae as a source of biofuel
11. UBC study establishes formula for predicting climate change impact on salmon stocks
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/18/2013)... 2013). A team of internationally recognized feline experts including ... from the University of Lincoln, U.K. and Dr Ilona ... invited by the International Society of Feline Medicine (ISFM) ... compile guidelines for veterinarians, owners and those working with ... the domestic cat. The new guidelines appear in the ...
(Date:6/17/2013)... to high levels of air pollution while pregnant were up ... as women who lived in areas with low pollution, according ... (HSPH). It is the first large national study to examine ... "Our findings raise concerns since, depending on the pollutant, 20% ... areas where risk of autism was elevated," said lead author ...
(Date:6/17/2013)... identified a new virus in patients with severe brain ... whether the virus is responsible for the symptoms of ... of 28 out of 644 patients with severe brain ... not in any of the 122 patients with non-infectious ... brain and central nervous system are often fatal and ...
Breaking Biology News(10 mins):Feline behavior experts release guidelines to improve the welfare of cats 2Exposure to high pollution levels during pregnancy may increase risk of having child with autism 2New virus isolated from patients with severe brain infections 2New virus isolated from patients with severe brain infections 3
... Samuel Waxman Cancer Research Foundation (SWCRF) has awarded 13 ... $1.54 million. The 16 grants represent a portion of ... award more than $2 million this year to cancer ... scientific minds in differentiation therapyreprogramming cancer cellsa hallmark of ...
... July 13 InQ Biosciences, a provider of innovative technologies for ... InQ™ Cell Research System during the fourth quarter of 2010. InQ is ... vivo environment for studying stem cells, plus nerve, brain, and other ... , , ...
... at the UK National Stem Cell Network annual science ... approach to treating heart attack and cardiomyopathy using stem ... Imperial College London, said "Recent clinical trials using stem ... terms of safety but unfortunately the bone marrow stem ...
Cached Biology News:The Samuel Waxman Cancer Research Foundation awards $1.54 million in research grants for 2010-2011 2The Samuel Waxman Cancer Research Foundation awards $1.54 million in research grants for 2010-2011 3InQ Biosciences Introduces First Fully Integrated Cell Research System 2InQ Biosciences Introduces First Fully Integrated Cell Research System 3Improving clinical use of stem cells to repair heart damage 2
(Date:6/18/2013)... Philadelphia, PA (PRWEB) June 18, 2013 ... fiber-optic Ball Lenses engineered of synthetic Sapphire and Glass ... stock sizes from Swiss Jewel Company , of ... performance by expanding and collimating the light beams without ... extreme optical clarity and natural durability (9 mohs) make ...
(Date:6/18/2013)... , June 18, 2013 ... the release of the HELM biomolecular representation standard ... source MIT licence. HELM (Hierarchical Editing ... wide range of biomolecules (e.g. proteins, nucleotides, antibody ... small-molecule and sequence-based informatics methodologies impractical or unusable. ...
(Date:6/18/2013)... Israel , June 18, 2013 ... Active Pharmaceutical Ingredients (APIs), generic and innovative intermediates, and finished ... that the company has been granted a United ... the US and Europe for the ... number 8,410,176 B2 is titled Intermediate Compounds and Processes ...
(Date:6/18/2013)... 2013   Lexicon Pharmaceuticals, Inc. (Nasdaq: ... on discovering breakthrough treatments for human disease, announced ... the company as its vice president of marketing, ... commercial experience to Lexicon, including both pre-launch planning ... areas. Mr. Northcott has held commercial ...
Breaking Biology Technology:Swiss Jewel Introduces the Crown Jewels of Fiber-Optic Connectors 2The Pistoia Alliance Releases HELM Biomolecular Representation Standard Open Source Tools 2Mapi Pharma Granted United States Patent for Pain Relief Medication "Tapentadol" 2John Northcott Joins Lexicon as Vice President of Marketing, Commercial Strategy and Operations 2John Northcott Joins Lexicon as Vice President of Marketing, Commercial Strategy and Operations 3
... HAMBURG, Germany, December 16 Eppendorf ... SP systems for,infringement of European patent EP 1 179 180 ... target compound". The import,ban covers any and all imports of ... authorities are required to confiscate any,violating products. , ...
... Mass., Dec. 15 Repligen Corporation (Nasdaq: RGEN ) ... funding to support the ongoing development of new treatments for ... grant will support the completion of preclinical GLP toxicology testing ... trials. Support from the MDA not only provides important ...
... ... developed and are opening up a new area of research for studies at the ... angle, meniscus height, evaporation rate and viscosity - all in a single force distance ... (PRWEB) ...
Cached Biology Technology:Eppendorf Successfully Initiates Import ban Against Nanosphere, Inc. for the Countries of the European Union 2Repligen Receives Second Research Grant from the Muscular Dystrophy Association to Support Friedreich's Ataxia Preclinical Development Program 2Repligen Receives Second Research Grant from the Muscular Dystrophy Association to Support Friedreich's Ataxia Preclinical Development Program 3New Constant Diameter NeedleProbes™ with Unique Ability to Measure Liquid Surface Properties by AFM 2New Constant Diameter NeedleProbes™ with Unique Ability to Measure Liquid Surface Properties by AFM 3
... PCR Workstation brings together UV irradiation and ... environment against PCR contamination! Quickly inactivate ... Maintain a clean environment with antimicrobial coated ... reagents within minutes with built-in 30-minute timer ...
... Recombinant Enterokinase (rEK) is a highly purified ... enterokinase, a serine protease which recognizes the ... (AspAspAspAspLys?) and has similar enzymatic activity (1). ... and purified to yield the highest activity ...
... of a Hybridizer and UV Crosslinker (254nm UV) ... , This unique, new design for the ... one location , Hybridizer and Crosslinker portions ... , The Crosslinker is also available as ...
Preparation Note: Prepared essentially by method of Singer, T.P., J. Biol. Chem., 174, 11 (1948). Quality Clarifier: Contains lipase Unit Definition: One unit will hydrolyze 1.0 μmole of p-ni...
Biology Products: