Navigation Links
New study evaluates noninvasive technology to determine heart disease
Date:8/29/2012

MINNEAPOLIS, MN August 29, 2012 A study published in the most recent issue of the Journal of the American Medical Association (JAMA) presented encouraging news regarding physicians' ability to determine blood flow and associated coronary artery disease (CAD) using noninvasive CT scanning technology. Data from the Determination of Fractional Flow Reserve by Anatomic Computed Tomographic Angiography (DeFACTO) study were presented on August 26 at the European Society of Cardiology Congress in Munich, Germany. John R. Lesser, MD, a Cardiologist and senior researcher at the Minneapolis Heart Institute Foundation, served as a principal investigator for the DeFACTO study and Minneapolis Heart Institute Foundation Cardiologist and senior researcher Robert Schwartz, MD directed the Integration Core Lab coordinating data from 17 sites worldwide.

"The study showed improved diagnostic accuracy with CT scanning when we also use a new technique called fractional flow reserve that identifies the rate of coronary blood flow and possible blockages in the arteries that may interfere with flow," said Robert Schwartz, MD.

Fractional flow reserve (FFR) has been identified as a procedure that may help to reduce unnecessary angiography and stenting when used. It requires a minimally invasive procedure. FFR with CT scanning requires no invasive procedure and has the potential to deliver equally useful data.

The objective of the DeFACTO study was to assess the diagnostic performance of CT with and without FFR for diagnosis of significant coronary stenosis. In its conclusion, the use of noninvasive FFRCT among patients with CAD was associated with improved diagnostic accuracy and discrimination.

"DeFACTO is worthy of note because, while it did not achieve it's endpoint, it definitely showed improved diagnostic accuracy using FFRCT vs. CT alone," stated Schwartz. "We are always looking to use the least invasive procedures to get the best results and DeFACTO indicates that we may soon have another useful tool in evaluating and treating heart disease."

In an editorial in JAMA, Manesh R. Patel, MD, Duke Clinical Research Institute, Duke University Medical Center, wrote, "The current report describes an important noninvasive technology that may improve existing care and has the potential to outperform established noninvasive technologies."

DeFACTO is a multi-center diagnostic performance study involving 252 stable patients with suspected or known CAD from 17 centers in 5 countries who underwent CT, invasive coronary angiography (ICA), FFR, and FFRCT between October 2010 and October 2011. The primary study outcome assessed whether FFRCT plus CT could improve the per-patient diagnostic accuracy. Among study participants and compared with obstructive CAD diagnosed by CT alone, FFRCT was associated with improved diagnostic accuracy and discrimination.


'/>"/>
Contact: Steve Goodyear
sgoodyear@mhif.org
612-863-1658
Minneapolis Heart Institute Foundation
Source:Eurekalert

Related biology news :

1. Study by UC Santa Barbara researchers suggests that bacteria communicate by touch
2. Law that regulates shark fishery is too liberal: UBC study
3. New study will help protect vulnerable birds from impacts of climate change
4. Study jointly led by UCSB researcher supports theory of extraterrestrial impact
5. BYU study: Using a gun in bear encounters doesnt make you safer
6. 15-year study: When it comes to creating wetlands, Mother Nature is in charge
7. Pycnogenol (French maritime pine bark extract) shown to improve menopause symptoms in new study
8. Crystal structure of archael chromatin clarified in new study
9. EU-funded study underlines importance of Congo Basin for global climate and biodiversity
10. University of Houston study shows BP oil spill hurt marshes, but recovery possible
11. Study demonstrates cells can acquire new functions through transcriptional regulatory network
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/26/2016)... and LONDON , ... Finacle, part of EdgeVerve Systems, a product subsidiary ... Onegini today announced a partnership to integrate the ...      (Logo: http://photos.prnewswire.com/prnh/20151104/283829LOGO ) ... provide their customers enhanced security to access and ...
(Date:4/19/2016)... 2016 The new GEZE SecuLogic ... web-based "all-in-one" system solution for all door components. It ... the door interface with integration authorization management system, and ... The minimal dimensions of the access control and the ... installations offer considerable freedom of design with regard to ...
(Date:4/15/2016)... 15, 2016 Research and ... Biometrics Market 2016-2020,"  report to their offering.  , ... , ,The global gait biometrics market is expected ... the period 2016-2020. Gait analysis generates ... be used to compute factors that are not ...
Breaking Biology News(10 mins):
(Date:5/4/2016)... (PRWEB) , ... May 04, 2016 , ... PBI-Gordon Corporation ... and Agricultural Sales. , Doug began his career at PBI-Gordon in February 1988, ... in a wide variety of roles, ranging from customer service to national product manager, ...
(Date:5/3/2016)... Boston, Massachusetts (PRWEB) , ... May 03, 2016 ... ... communities will gather at Boston CEO 2016 on May 31st and June 1st ... off-the-record networking forum for leading executives in the life sciences, offering exclusive access ...
(Date:5/3/2016)... , May 3, 2016  Dr. Thomas ... surgeon in The Woodlands, Texas , ... 24 percent of treated fat cells in just 25-minutes, ... Close to 90 percent of Americans report feeling bothered ... Nonsurgical fat reduction procedures are a growing industry. This ...
(Date:5/2/2016)... ... May 02, 2016 , ... StarNet Communications Corp, ( http://www.starnet.com/ ... addition of three Secure Remote Desktop modules to its flagship X-Win32 PC X server. ... and Unix servers to the user’s PC over encrypted SSH. , Traditionally, users of ...
Breaking Biology Technology: