Navigation Links
New studies show spinal cord injury and ALS respond to cell transplantation
Date:7/19/2012

y not only confirmed the established link between microglial activation and inflammatory cytokines, but also demonstrated that functional recovery might be attributed to immunomodulatory effects rather than cell replacement. They also recommended that autologous (self-donated) MSCs, rather than human-derived MSCs, should be used in subsequent studies to "suppress undesirable immune response."

Contact: Dr. Sung-Rae Cho, Department and Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine, 134 Shinchon-dong, Seodaemun-gu, Seoul, Korea 120-752
Tel: +82 2 2228-3715 Fax: +82 2 363-2795 Email: srcho918@yuhs.ac

Citation: Seo, J. H.; Jang, I. K.; Kim, H.; Yang, M. S.; Lee, J. E.; Kim, H. E.; Eom, Y-W.; Lee, D-H.; Yu, J. H.; Kim, J. Y.; Kim, H. O.; Cho, S-R. Early immunomodulation by intravenously transplanted mesenchymal stem cells promotes functional recovery in spinal cord injured rats. Cell Med. 2(2):55-67; 2011.

Bone marrow cell transplantation coupled with stimulating factor offers neuroprotective and angiogenic effects in ALS animal models

In this the first report showing the effects of bone marrow cell transplantation (BMT) combined with granulocyte colony-stimulating factor (GCSF) in mouse models of ALS, researchers from Okayama University, Japan demonstrated that the co-treatment potentially confers neuroprotective and angiogenic (blood vessel growth) effects on the test mice.

"Combined treatment with BMT and GCSF delayed disease progression and prolonged the survival of G93A mice while BMT or GCSF treatment alone did not," said corresponding author professor Koji Abe of the Department of Neurology in the Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences. "In addition, the mice treated with BMT and GCSF also showed a reduction in motor neuron loss, induced neuronal precursor cell proliferation, and th
'/>"/>

Contact: David Eve
cellmedicinect@gmail.com
Cell Transplantation Center of Excellence for Aging and Brain Repair
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. FirstMark Scientific Board of Advisors Meet to Discuss New Clinical Studies for PREvent
2. Preclinical studies use specialized ultrasound to detect presence of cancer
3. GSA Bulletin presents studies in Antarctica, Italy, Mexico, Algeria, Mongolia, and more
4. 2 Cell Transplantation studies impact dental stem cell research for therapeutic purposes
5. Miniature Sandia sensors may advance climate studies
6. Improving equine health: Research studies vaccinations to protect newborn foals
7. Autism Speaks awards $1.1 million to fund high priority studies
8. Collaborative preclinical efficacy studies suggest a new target for drug addiction treatment
9. Studies reveal structure of EV71, a virus causing childhood illnesses
10. Neuroprotective dietary supplements for chronic spinal cord injury
11. Neural stem cell transplants for spinal cord injury maximized by combined, complimentary therapies
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/22/2014)... , Dec. 22, 2014  The 2014 Holiday Season ... as Acuity Market Intelligence reports that the long anticipated ... forecasts that intensifying demand for smart phones, tablets, and ... global market of 2.5 billion users with nearly 4.8 ...
(Date:12/19/2014)... , Dec. 18, 2014  23andMe, Inc., the leading personal genetics ... fine-scale differences in genetic ancestry of individuals from across ... first arrived more than four hundred years ago, ... place for peoples from different continents. This study illuminates how ...
(Date:12/17/2014)... Dec. 15, 2014 The Defense Logistics Agency is ... and prevent counterfeit microcircuits from entering into its supply ... in-house microcircuit anti-counterfeit initiative dubbed DNA marking. The capability ... their reliability throughout the supply chain. The new quality ...
Breaking Biology News(10 mins):First Season of Holiday Shopping with Mobile Biometric Payments Wraps Up With a Present for Biometrics Industry: A Rosy Forecast for More Than 2 Billion Users of 4.8 Billion Mobile Biometric Devices by 2020 223andMe Study Sketches Genetic Portrait of the United States 223andMe Study Sketches Genetic Portrait of the United States 323andMe Study Sketches Genetic Portrait of the United States 4Defense Logistics Agency Launches DNA Marking Capability to Strengthen Microcircuit Supply Chain 2Defense Logistics Agency Launches DNA Marking Capability to Strengthen Microcircuit Supply Chain 3
... first reported case in Asia of primate-to-human transmission of simian ... primates that so far has not been shown to cause ... monkey to a human took place at a monkey temple ... of the journal Emerging Infectious Diseases. Even though this particular ...
... States Department of Agriculture (USDA) has positively identified the pathogenic ... in Mongolia by field veterinarians from the Wildlife Conservation Society ... occurring in wild migratory birds with no apparent contact to ... for a health survey of wild bird populations in the ...
... modern oceanography is how animals in the deep sea ... Bay Aquarium Research Institute (MBARI) recently published a paper ... that live on the deep seafloor off the coast ... deep-sea video, Bruce Robison and his colleagues found that ...
Cached Biology News:Primate virus jumps species barrier to humans for first time in Asia 2Primate virus jumps species barrier to humans for first time in Asia 3Bird samples from Mongolia confirmed as H5N1 avian flu 2Bird samples from Mongolia confirmed as H5N1 avian flu 3'Sinkers' provide missing piece in deep-sea puzzle 2'Sinkers' provide missing piece in deep-sea puzzle 3'Sinkers' provide missing piece in deep-sea puzzle 4
(Date:1/22/2015)... Eckert & Ziegler Vitalea Science (EZVS), ... to the pharmaceutical and biotech industry, has announced that ... the position of Director of Science & Technology. , ... experience in drug metabolism and bioanalysis to EZVS in ...
(Date:1/22/2015)... Cambridge Semantics, the leading provider of smart data solutions ... a record-breaking year across the board for the company. ... Platform and our Smart Data solutions, our customers were able ... led to record growth for the company in 2014,” said ...
(Date:1/22/2015)... zFlo Motion , a US leader in biomechanics ... from a new partner. STT-Systems has developed an ... years, with offerings in the optical-motion capture, 3D scanning, and ... measurement unit), iSen, is opening eyes around the world. With ...
(Date:1/22/2015)... NEW BRUNSWICK , Nueva Jersey , 22 ... Award for Biomedical Research abre hoy su llamada ... las personas cuya investigación científica ha hecho, o tiene ... de la salud humana. Las nominaciones se aceptarán hasta ...
Breaking Biology Technology:Eckert & Ziegler Vitalea Science appoints Mark Seymour, PhD as Director of Science & Technology 2Eckert & Ziegler Vitalea Science appoints Mark Seymour, PhD as Director of Science & Technology 3Cambridge Semantics Announces Record Results for 2014 23D Motion Capture Just Got Easy 2El Dr. Paul Janssen Award for Biomedical Research emite su llamada a los nominados para 2015 2El Dr. Paul Janssen Award for Biomedical Research emite su llamada a los nominados para 2015 3El Dr. Paul Janssen Award for Biomedical Research emite su llamada a los nominados para 2015 4
... Madison, Wis. Can a Mac really be hacked in ... University of Wisconsin-Madison systems engineer, who criticized recent media reports for ... which the owner of a computer gave out login accounts to ... for someone who had been given access to the computer to ...
... last week's Fusion2006 was to make information ... that presenters delivered, private-sector CIOs would be well advised ... there was a dominant theme of the second annual ... linkage - linkage with their CEOs and linking information ...
... — Competition is heating up in Waukesha for ... residents. , ,Three firms want to build the infrastructure ... bandwidth to Internet service providers. After waiting several years ... city would start to receive royalties. , ,Midwest Fiber, ...
Cached Biology Technology:IT can't be separate from core business 2
... Rabbit polyclonal to MSY2/YBOX2 ( Abpromise ... Antigen: Synthetic peptide ... the C-terminus of Human MSY2/YBOX2. ... proprietary) (Peptide available ...
...
Request Info...
Purified Mouse anti-Hu LAT (pY226) Storage Temperature: Refrigerate(2 to 8C)...
Biology Products: