Navigation Links
New step forward in search for solution to infection puzzle
Date:8/6/2008

Scientists at the University of York have helped to reveal more about the way bacteria can attach to human tissues.

The study could help in the development of new treatments for serious heart conditions such as infective endocarditis.

The researchers studied the way a protein found on the surface of the bacteria Staphylococcus aureus binds to a human protein called fibronectin. Their discovery is an important step in understanding how bacteria attach to the surface of blood vessels during infection.

The high-resolution structures of parts of the bacterial protein in complex with multiple fibronectin domains reveals the efficiency with which the bacterial molecule can bind several copies of the human protein, a feature thought to play a role in infection.

Dr Jennifer Potts of the Departments of Biology and Chemistry at York, who led the research said: "Interactions of S. aureus with fibronectin were first reported more than 30 years ago, and yet we still don't understand precisely how and why the bacteria target this human protein.

"Our studies provide a significant step toward solving that issue and could help the future development of new treatments for rare but serious conditions such as infective endocarditis, an infection of the lining or valves of the heart."


'/>"/>

Contact: David Garner
dcg501@york.ac.uk
44-019-044-32153
University of York
Source:Eurekalert

Page: 1

Related biology news :

1. Graduate Education in Physics: Which Way Forward?
2. Is hybridoma production about to take a quantum leap forward?
3. A step forward in virology
4. AVAC comments on NIAID decision not to move forward with PAVE 100 Trial
5. Research shows skeleton to be endocrine organ
6. Newly created cancer stem cells could aid breast cancer research
7. Dominant cholesterol-metabolism ideas challenged by new research
8. Researchers identify proteins involved in new neurodegenerative syndrome
9. Texas researchers and educators head for Antarctica
10. MGH researchers describe new way to identify, evolve novel enzymes
11. University of Pennsylvania researchers develop formula to gauge risk of disease clusters
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/22/2016)... PUNE, India , March 22, 2016 ... new market research report "Electronic Sensors Market for ... Fingerprint, Proximity, & Others), Application (Communication & ... and Geography - Global Forecast to 2022", ... consumer industry is expected to reach USD ...
(Date:3/21/2016)... Massachusetts , March 22, 2016 ... facial recognition with passcodes for superior security   ... ), a leading provider of secure digital communications services, ... their biometric technology and offer enterprise customers, particularly those ... secure facial recognition and voice authentication within a mobile ...
(Date:3/17/2016)... ABI Research, the leader in transformative ... market will reach more than $30 billion by ... Consumer electronics, particularly smartphones, continue to boost the ... reach two billion shipments by 2021 at a ... Research Analyst at ABI Research. "Surveillance is also ...
Breaking Biology News(10 mins):
(Date:5/3/2016)... ... , ... According to world renowned prostate cancer surgeon, Dr. David B. ... two main treatment options: surgery or radiation. Based on a patient’s goals, disease state, ... enabled doctors to administer higher doses of radiation to prostate cancer patients ...
(Date:5/2/2016)... ... May 02, 2016 , ... StarNet Communications Corp, ( http://www.starnet.com/ ) a leading ... Secure Remote Desktop modules to its flagship X-Win32 PC X server. The new ... to the user’s PC over encrypted SSH. , Traditionally, users of PC X servers ...
(Date:4/29/2016)... ... 29, 2016 , ... Amendia, Inc., a leading designer, developer, ... the completion of a significant transaction and partnership that positions Amendia for accelerated ... Kohlberg & Company, L.L.C. (“Kohlberg”), a leading private equity firm specializing in ...
(Date:4/29/2016)... ... ... Intelligent Implant Systems announced today that the two-level components for the Revolution™ ... States. These components expand the capabilities of the system and allow Revolution™ to ... of 2015, the company has seen significant sales growth in 1Q 2016, and the ...
Breaking Biology Technology: