Navigation Links
New stem cell research points to early indicators of schizophrenia
Date:5/13/2014

LA JOLLAUsing new stem cell technology, scientists at the Salk Institute have shown that neurons generated from the skin cells of people with schizophrenia behave strangely in early developmental stages, providing a hint as to ways to detect and potentially treat the disease early.

The findings of the study, published online in April's Molecular Psychiatry, support the theory that the neurological dysfunction that eventually causes schizophrenia may begin in the brains of babies still in the womb.

"This study aims to investigate the earliest detectable changes in the brain that lead to schizophrenia," says Fred H. Gage, Salk professor of genetics. "We were surprised at how early in the developmental process that defects in neural function could be detected."

Currently, over 1.1 percent of the world's population has schizophrenia, with an estimated three million cases in the United States alone. The economic cost is high: in 2002, Americans spent nearly $63 billion on treatment and managing disability. The emotional cost is higher still: 10 percent of those with schizophrenia are driven to commit suicide by the burden of coping with the disease.

Although schizophrenia is a devastating disease, scientists still know very little about its underlying causes, and it is still unknown which cells in the brain are affected and how. Previously, scientists had only been able to study schizophrenia by examining the brains of patients after death, but age, stress, medication or drug abuse had often altered or damaged the brains of these patients, making it difficult to pinpoint the disease's origins.

The Salk scientists were able to avoid this hurdle by using stem cell technologies. They took skin cells from patients, coaxed the cells to revert back to an earlier stem cell form and then prompted them to grow into very early-stage neurons (dubbed neural progenitor cells or
'/>"/>

Contact: Chris Emery
cemery@salk.edu
858-453-4100
Salk Institute
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Study by UC Santa Barbara researchers suggests that bacteria communicate by touch
2. Research reveals first evidence of hunting by prehistoric Ohioans
3. Diabetes Research Institute develops oxygen-generating biomaterial
4. APS issues new policy requiring identification of sex or gender in reporting scientific research
5. UC Santa Barbara researchers discover genetic link between visual pathways of hydras and humans
6. Study jointly led by UCSB researcher supports theory of extraterrestrial impact
7. U of Alberta researcher steps closer to understand autoimmune diseases
8. Research on flavanols and procyanidins provides new insights into how these phytonutrients may positively impact human health
9. A project to research biological and chemical aspects of microalgae to fuel approach
10. Scripps Research discoveries lead to newly approved drug for infant respiratory distress syndrome
11. Researchers attempt to solve problems of antibiotic resistance and bee deaths in one
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New stem cell research points to early indicators of schizophrenia
(Date:4/13/2015)... According to a recently ... & Opportunities, 2020", the global biometrics market is ... till 2020. The biometrics market is garnering attention ... review of biometric management systems. The constant development ... greater efficiency, are resulting in increasing installation of ...
(Date:4/9/2015)... SAN JOSE, Calif. , April 9, 2015 /PRNewswire/ ... of human interface solutions, announced today that it will ... 2015 on Thursday, April 23, 2015, after the close ... call for analysts and investors at 2:00 p.m. PT ... information.    To participate on the live ...
(Date:4/2/2015)... April 2, 2015 In ... by far outperforms the strongest competitors, showing outstanding ... accuracy, the system is capable of a throughput ... proves up to be ten times faster than ... runner-up performance.      (Photo: http://photos.prnewswire.com/prnh/20150402/738673-a ...
Breaking Biology News(10 mins):Global Biometrics Market to Cross US$ 21 Billion by 2020: TechSci Research 2Synaptics to Report Third Quarter Results on April 23 2DERMALOG AFIS Emerges as Performance Winner in NIST Benchmark Test 2DERMALOG AFIS Emerges as Performance Winner in NIST Benchmark Test 3
... waste has been produced for a long time, there is ... which remains hazardous for up to 130 000 years. In ... and Responsibility, Mats Andrn, professor in History of Ideas and ... issue from a humanistic perspective. The nuclear waste debate ...
... studying 1,600-year-old cotton from the banks of the Nile have ... evolution has occurred in a major crop group within the ... an insight into the dynamics of agriculture in the ancient ... such as climate change and water scarcity. The researchers, ...
... being among his most vibrant and celebrated works, Vincent van ... genetic basis has, until now, been a mystery. In a ... University of Georgia scientists reveal the mutation behind the distinctive, ... painted more than 100 years ago. The most common ...
Cached Biology News:Postpone the nuclear waste decision 2Ancient Egyptian cotton unveils secrets of domesticated crop evolution 2Ancient Egyptian cotton unveils secrets of domesticated crop evolution 3Genetic mutation depicted in van Gogh's sunflower paintings revealed by scientists 2
(Date:4/28/2015)... 28, 2015 CargoSense, a Virginia-based ... on supply chain logistics, today announced that it ... round, bringing total investment proceeds to $2.5 million. ... venture capital firms IrishAngels and Middleburg Capital Development. ... also participated in the round. , CargoSense ...
(Date:4/28/2015)... , April 28, 2015  Adaptive Biotechnologies ... conducted with researchers at The University of Texas ... next-generation sequencing-based approach to identification and quantification of ... sequences in the blood of people with classical ... British Journal of Haematology , represent a ...
(Date:4/28/2015)... drug discovery company, Novogen Limited (ASX: NRT; NASDAQ: NVGN) ... NASDAQ informing it that it had regained full compliance ... In November 2014, the Company received a deficiency ... plan to regain compliance with the Listing Rule, which ... equity as of June 30, 2014; (ii) at least ...
(Date:4/28/2015)... Claremont, CA (PRWEB) April 28, 2015 ... Association, more than 450,000 patients receive medical treatment from ... acute management of burn injury, extensive formation of scars ... of these burn patients for which there is no ... skin that prevent normal movement and can cause permanent ...
Breaking Biology Technology:CargoSense Completes Seed Round Offering By Raising $2.5 Million 2CargoSense Completes Seed Round Offering By Raising $2.5 Million 3CargoSense Completes Seed Round Offering By Raising $2.5 Million 4Adaptive Biotechnologies and Researchers from MD Anderson Cancer Center Demonstrate Ability to Detect Hodgkin's Lymphoma in Blood 2Adaptive Biotechnologies and Researchers from MD Anderson Cancer Center Demonstrate Ability to Detect Hodgkin's Lymphoma in Blood 3Novogen Regains Full Compliance with NASDAQ Listing Rule 2Novogen Regains Full Compliance with NASDAQ Listing Rule 3Synedgen Burn Treatment Results Presented at Premier Wound Conference 2Synedgen Burn Treatment Results Presented at Premier Wound Conference 3
... CryoLife, Inc., (NYSE: CRY ) ... today announced that it has received a Humanitarian Use Device ... its CryoValve® SG aortic human heart valve. The HUD ... Exemption (HDE) for the CryoValve SG aortic human heart valve, ...
... Jobs and Economic Revitalization Across State , INDIANAPOLIS ... (NRDC) will release a major new report Wednesday (October 7, ... to prove a major boost to farm incomes and rural ... and ample access to the raw materials for biofuels, biopower ...
... Cryo-Cell International, a global leader in stem cell innovation, ... against breast cancer through research and development using stem ... Breast Cancer Awareness Month, Cryo-Cell is supporting Susan G. ... which enables women to collect and cryopreserve stem cells ...
Cached Biology Technology:CryoLife Receives Humanitarian Use Device Designation for SynerGraft(R) Processed Human Aortic Heart Valves 2CryoLife Receives Humanitarian Use Device Designation for SynerGraft(R) Processed Human Aortic Heart Valves 3CryoLife Receives Humanitarian Use Device Designation for SynerGraft(R) Processed Human Aortic Heart Valves 4A New Economic Future for Rural Indiana?: Study to Show How Renewable Energy Could Trigger Boom for Economically Struggling Areas in State 2Cryo-Cell International's Stem Cell Research and Development Helps the Fight Against Breast Cancer 2Cryo-Cell International's Stem Cell Research and Development Helps the Fight Against Breast Cancer 3
... samples for freezing point determinations. Includes built-in printer, keypad, and software for ... RS-232 port. Microprocessor-controlled autocalibration. Two-step Calibration. ... ... ...
The Light Diagnostics Calicivirus Genotype 1&2 Typing OligoDetect assay is applicable for the qualitative detection of calicivirus RNA generated by an in-house validated in vitro nucleic acid amplifi...
X-Gal...
Recombinant Rat CINC-2 alpha, CF...
Biology Products: