Navigation Links
New sleep cycle discovery explains why fatty diets during pregnancy make kids obese
Date:11/22/2010

The link between sleeping and obesity is drawn tighter as a new research published online in the FASEB Journal (http://www.fasebj.org/content/early/2010/11/19/fj.10-172080.abstract) study shows that what your mother ate when she was pregnant may make you obese or overweight by altering the function of genes (epigenetic changes) that regulate circadian rhythm. In the report, pregnant primate females consuming a high-fat diet altered the function of fetal genes that regulate circadian rhythm (including appetite and food intake) during development. The offspring also had non-alcoholic fatty liver disease.

"It is our hope that our studies will continue to guide research aimed at understanding the pivotal role that maternal health plays in guiding the health of the next generation," said Kjersti Aagaard-Tillery, M.D., Ph.D., a researcher involved in the work from the Department of Obstetrics and Gynecology at Baylor College of Medicine in Houston. "We are enthusiastic that our research will give hope that even small changes, such as improving one's diet in pregnancy and during breastfeeding, will translate into a lower chance for obesity in our next generation."

To make this discovery, Aagaard-Tillery and colleagues studied three groups of Japanese macaque primates. One group was fed a 12 percent fat diet (the control group). The second group was fed a 35 percent fat or high-fat diet and the third group was fed the high-fat diet for up to five years and then switched back to the control diet. Each group maintained their specific diet prior to conception and throughout pregnancy. Offspring from the high-fat group developed non-alcoholic fatty liver disease; experienced changes in histones (the core set of proteins which DNA wrap around), and had altered metabolic profiles and circadian rhythms. Results also showed that the genes in the fetal liver, which are
'/>"/>

Contact: Cody Mooneyhan
cmooneyhan@faseb.org
301-634-7104
Federation of American Societies for Experimental Biology
Source:Eurekalert

Page: 1 2

Related biology news :

1. Analyzed relation between sleep disorders and risk perception by drivers with disorder
2. Researchers study sleep apnea and lack of oxygen
3. WSU researchers discover key mechanism behind sleep
4. New link between pollution, temperature and sleep-disordered breathing
5. Biologists identify genes regulating sleeping and feeding
6. HJF research psychologist receives Sleep Research Societys Young Investigator Award
7. Extremes of sleep related to increased fat around organs
8. Babies and sleep: Another reason to love naps
9. Sleeping Beauty -- Molecule of the Year
10. Scientists hope to end sleeping sickness by making parasite that causes it self-destruct
11. Sleeping Beauty hooks up with herpes to fight brain disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/29/2014)... and number of connections in transcription factor networks (TFNs) ... a study published in PLOS Computational Biology ... signature contributes to a network,s resilience against mutations. ... assortativity of TFN models has a greater effect on ... of assortativity," said Dov A. Pechenick, PhD, lead author ...
(Date:8/29/2014)... in German . ... is considered the oldest form of communication. Acting as ... example, the sexual attraction between males and females. Fish ... coordinate reproductive behavior in males and females. Scientists at ... Algarve in Faro, Portugal, and at the Max Planck ...
(Date:8/29/2014)... a cell,s nucleus, chromosomal DNA is tightly bound ... biologists call chromatin. Until about two decades ago, ... mere packing material around which the glamorous DNA ... a greater appreciation for how DNA/histone interactions govern ... research institutions studying the sequence of the genome ...
Breaking Biology News(10 mins):Assortativity signatures of transcription factor networks contribute to robustness 2Ready for mating at the right time 2Ready for mating at the right time 3'K-to-M' histone mutations: How repressing the repressors may drive tissue-specific cancers 2'K-to-M' histone mutations: How repressing the repressors may drive tissue-specific cancers 3
... 25, 2013) A team of researchers at The ... Scott Noggle, PhD, Director of the NYSCF Laboratory and ... Alzheimer,s Disease, and Michael W. Nestor, PhD, a NYSCF ... three-dimensional cultures of induced pluripotent stem (iPS) cells called ...
... California sagebrush in the southern part of the ... populations in the north, according to UC Irvine researchers ... with the Center for Environmental Biology. The results ... Change Biology , will assist land management and policy ...
... 2013 Listed below are the selected highlights for the ... Genetics . The April issue is available online ... Vol. 193, April 2013, Copyright 2013. Please feel ... these articles on a wide array of topics including methods, ...
Cached Biology News:NYSCF scientists develop 3-D stem cell culture technique to better understand Alzheimer's disease 2Southern California sagebrush better suited to climate change, UCI study finds 2Genetics Society of America's Genetics journal highlights for April 2013 2Genetics Society of America's Genetics journal highlights for April 2013 3Genetics Society of America's Genetics journal highlights for April 2013 4
(Date:8/29/2014)... 2014  Pfenex Inc. (NYSE MKT: PFNX), a ... high-value and difficult to manufacture proteins including biosimilar ... financial results for the second quarter ended June ... of our initial public offering, we have the ... candidates, derived from our proprietary protein expression platform," ...
(Date:8/29/2014)... Pittcon is pleased to announce that the ... Horiba Scientific, have organized a session on nanotechnology for ... , Asia’s largest analytical and scientific instruments show, will ... , The four speakers in this U.S. symposium, ... to Single Cells” will present their use of nanotechnology ...
(Date:8/29/2014)... Due to a misstatement posted by the ... Cell Technology Center, LLC ( ASCTC ) was reported as ... that might benefit ALS patients. Because of ASCTC's exclusive ... technologies and therapeutic applications, FRC listed ASCTC as one of ... who wish not to support research that requires the death ...
(Date:8/28/2014)... Best Sanitizers, Inc., a leader in ... industry, is asking industry professionals to prepare for fall ... E2 soap they’re currently using to the Best Sanitizers’ ... Hand hygiene is critical to fighting cross-contamination and the ... key criteria are identified to evaluate the effectiveness of ...
Breaking Biology Technology:Pfenex Reports Second Quarter 2014 Results and Provides Business Update 2Pfenex Reports Second Quarter 2014 Results and Provides Business Update 3Pfenex Reports Second Quarter 2014 Results and Provides Business Update 4Pfenex Reports Second Quarter 2014 Results and Provides Business Update 5Pfenex Reports Second Quarter 2014 Results and Provides Business Update 6Pfenex Reports Second Quarter 2014 Results and Provides Business Update 7Pfenex Reports Second Quarter 2014 Results and Provides Business Update 8Fifth Annual U.S. Symposium at JASIS Organized by Pittcon’s Program Chairman Hub MacDonald 2The Adult Stem Cell Technology Center, LLC Declines ALS Ice Bucket Challenge Donors Wishing to Support Ethical Research for New Stem Cell Therapies 2The Adult Stem Cell Technology Center, LLC Declines ALS Ice Bucket Challenge Donors Wishing to Support Ethical Research for New Stem Cell Therapies 3Best Sanitizers, Inc. Asks Food Industry Professionals: With Fall Harvest On the Way, Is Your E2 Hand Soap Up to the Task? 2
... April 25 Kosan Biosciences,Incorporated (Nasdaq: KOSN ) ... May 1, 2008, after market close., The announcement ... by a conference call and live webcast on May ... Interested parties may access the live,call by dialing 888.680.0878 ...
... and Collaborators Publish Study in Science, ... GmbH, the,leading developer of RAFT intervention therapeutics, ... Science demonstrating a potential novel strategy,for therapeutic ... targeting,discrete sub-compartments in the cell membrane (RAFTS). ...
... Gen-Probe Incorporated,(Nasdaq: GPRO ) announced today that the ... Conference on May 1, 2008 at,approximately 4:20 p.m. Eastern ... may be accessed through a link on the investors ... will be,available for 30 days following the event., ...
Cached Biology Technology:Kosan Announces May 1, 2008 Conference Call and Webcast of First Quarter 2008 Financial Results 2Novel Approach to Treat Alzheimer's and Other Diseases Offered by Targeting Cell Membrane RAFTS 2Novel Approach to Treat Alzheimer's and Other Diseases Offered by Targeting Cell Membrane RAFTS 3Novel Approach to Treat Alzheimer's and Other Diseases Offered by Targeting Cell Membrane RAFTS 4Gen-Probe to Webcast Presentation at Morgan Stanley Global Healthcare Unplugged Conference 2
Can be used for the quantitative recovery of small amounts of nucleic acids within dilute solutions. 5mg/ml...
RAB32, member RAS oncogene family, mRNA (cDNA clone MGC:13500 IMAGE:4280407), complete cds...
Can be used for the quantitative recovery of small amounts of nucleic acids within dilute solutions. 5mg/ml...
APOPTAG® Plastic Coverslips are designed to be custom fitted to the specific APOPTAG® kit application. Each coverslip has 2.5 x 1 dimensions....
Biology Products: