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New scanning strategy could help develop heart disease treatments
Date:12/12/2011

p>Dr Shannon Amoils, Research Advisor at the BHF, said: "Aortic stenosis is the most common reason for having a heart valve operation in the UK. It would be much better for patients if we could either prevent the condition or treat it with a drug at an early stage. But the fact is that there are currently no medicines for the condition, and no accurate way of predicting how quickly it will progress.

"We're delighted to have been able to fund this study, which has used state-of-the-art imaging technology to reveal clues about the biology underlying aortic stenosis and how it progresses. The researchers have shown that calcification, or 'hardening', of the aortic valve may be the most important process underlying its progressive narrowing. This could explain why attempts to treat patients by targeting the inflammation in the valve have not worked, and it offers hope that a change of strategy targeting the calcification process might prove more successful."


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Contact: Tara Womersley
tara.womersley@ed.ac.uk
44-131-650-9836
University of Edinburgh
Source:Eurekalert

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