Navigation Links
New robot system to test 10,000 chemicals for toxicity
Date:3/10/2011

Several federal agencies, including the National Institutes of Health, today unveiled a new high-speed robot screening system that will test 10,000 different chemicals for potential toxicity. The system marks the beginning of a new phase of an ongoing collaboration, referred to as Tox21, that is working to protect human health by improving how chemicals are tested in the United States.

The robot system, which is located at the NIH Chemical Genomics Center (NCGC) in Rockville, Md., was purchased as part of the Tox21 collaboration. Tox21 was established in 2008 between the National Institute of Environmental Health Sciences National Toxicology Program (NTP), the National Human Genome Research Institute (NHGRI), and the U.S. Environmental Protection Agency (EPA), with the addition of the U.S. Food and Drug Administration (FDA) in 2010. Tox21 merges existing agency resources (research, funding, and testing tools) to develop ways to more effectively predict how chemicals will affect human health and the environment.

The 10,000 chemicals screened by the robot system include compounds found in industrial and consumer products, food additives, and drugs. A thorough analysis and prioritization process from more than 200 public databases of chemicals and drugs used in the United States and abroad was conducted to select the initial 10,000 chemicals for testing. Testing results will provide information useful for evaluating if these chemicals have the potential to disrupt human body processes enough to lead to adverse health effects.

"Tox21 has used robots to screen chemicals since 2008, but this new robotic system is dedicated to screening a much larger compound library," said NHGRI Director Eric Green, M.D., Ph.D. The director of the NCGC at NHGRI, Christopher Austin, M.D., added "The Tox21 collaboration will transform our understanding of toxicology with the ability to test in a day what would take one year for a person to do by hand."

"The addition of this new robot system will allow the National Toxicology Program to advance its mission of testing chemicals smarter, better, and faster," said Linda Birnbaum, Ph.D., NIEHS and NTP director. "We will be able to more quickly provide information about potentially dangerous substances to health and regulatory decision makers, and others, so they can make informed decisions to protect public health."

Tox21 has already screened more than 2,500 chemicals for potential toxicity, using robots and other innovative chemical screening technologies.

"Understanding the molecular basis of hazard is fundamental to the protection of human health and the environment," said Paul Anastas, Ph.D., assistant administrator of the EPA Office of Research and Development. "Tox21 allows us to obtain deeper understanding and more powerful insights, faster than ever before."

"This partnership builds upon FDA's commitment to developing new methods to evaluate the toxicity of the substances that we regulate," said Janet Woodcock, M.D., director of the FDA Center for Drug Evaluation and Research.


'/>"/>

Contact: Robin Mackar
rmackar@niehs.nih.gov
919-541-0073
NIH/National Institute of Environmental Health Sciences
Source:Eurekalert

Related biology news :

1. Robotic surgery lowers risk of a rare but serious complication of gastric bypass
2. Captain Birdseyes robotic nose
3. International Journal of Social Robotics debuts at Springer
4. Microbot motors fit to swim human arteries
5. UK robot sub searches for signs of melting 60 km into an Antarctic ice shelf cavity
6. Autonomous robot detects shrapnel
7. Pinhead-size worms + robot = new antibiotics
8. Harvard research team receives $10M NSF grant to develop small-scale mobile robotic devices
9. New robot travels across the seafloor to monitor the impact of climate change on deep-sea ecosystems
10. Caltech scientists create robot surrogate for blind persons in testing visual prostheses
11. Cockroaches offer inspiration for running robots
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/9/2016)... , March 9, 2016 This BCC ... future states of the RNA Sequencing (RNA Seq) market ... such as instruments, tools and reagents, data analysis, and ... various segments of the RNA-Sequencing market such as RNA-Sequencing ... Identify the main factors affecting each segment and forecast ...
(Date:3/8/2016)... 8, 2016   Valencell , the leading ... it has secured $11M in Series D financing. ... new venture fund being launched by UAE-based financial ... existing investors TDF Ventures and WSJ Joshua Fund. ... its triple-digit growth and accelerate its pioneering innovation ...
(Date:3/3/2016)... SOTO, Kansas , March 3, 2016 ... Oncimmune,s Early CDT®-Lung, a blood test to aid ... cancer Early CDT®-Lung test to its clients ... Early CDT®-Lung test to its clients which include ... a leader in early cancer detection, today announced a ...
Breaking Biology News(10 mins):
(Date:5/4/2016)... CA (PRWEB) , ... May 04, 2016 , ... ... Well, look no further than LaJollaCooks4u, San Diego’s premiere hands-on cooking experience. Offering ... need to give mom an experience she won’t forget. , Guests that visit ...
(Date:5/4/2016)... ... ... Proove Biosciences, Inc. , the commercial and research leader in personalized pain ... partnership is designed to advance research in pain genetics in an effort to bring ... new agreement, researchers at Proove Biosciences are able to collaborate with Luda Diatechnko, MD, ...
(Date:5/4/2016)... , May 4, 2016  Bayer today ... oncology compound Stivarga ® (regorafenib) tablets for ... (HCC) has met its primary endpoint of a ... called RESORCE, evaluated the efficacy and safety of ... progressed after treatment with sorafenib. The safety and ...
(Date:5/4/2016)... New York, NY (PRWEB) , ... May 04, 2016 , ... ... neurofibromatosis (NF), a genetic disorder that causes tumors to grow on nerves throughout the ... treatment or cure. , Through numerous community events held during the month of May, ...
Breaking Biology Technology: