Navigation Links
New research shows how gene function drives natural selection in important class of genetic elements
Date:12/10/2008

Athens, Ga. Transposons are the Clark Kents of a genome. Apparently mild-mannered and inconsequential but with sudden bursts of activity, these free-floating bits of genetic material have for millions of years been sneaking into the genetic maps of plants and animals, dramatically increasing a genome's size.

For years, researchers thought that most of this DNA was passive "junk" and knew little about it. New findings, however, are peeling back the odd and baffling world of transposons. Now, researchers at the University of Georgia have just found that natural selection on gene function is driving the evolution of one kind of transposable element called the LTR retrotransposon. (LTR refers to the "long terminal repeat"a repetition of a recognizable sequence of nucleotides, the chemical bases that make up strands of DNA.)

"The lab of Professor Jeff Bennetzen at UGA discovered that this class of mobile DNA comprises more than half of most plant genomes and has led the way in determining the extraordinary rates of both amplification and removal of this type of repetitive element," said Regina Baucom, a genetics post-doctoral research assistant at UGA and lead author of the research.

Understanding the evolutionary pressures between host genome and transposable element will in the future be of interest to those studying retroviruses, which evolved from retrotransposons. There are a number of animal and human diseases caused by retroviruses including HIV/AIDS, avian leukosis and feline leukemia.

"Because LTR retrotransposons are abundant and impact host genomes, we wanted to determine the influence of natural selection on their evolution," said Baucom. "We find that the genes involved in their replication are subject to Darwinian evolutionthe same evolutionary processes that affect species."

Other authors of the paper just published in the online version of the journal Genome Research, were Jeff Bennetzen, in wh
'/>"/>

Contact: Phil Williams
phil@franklin.uga.edu
706-542-8501
University of Georgia
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. UNH researchers track lobster migrations to improve population estimates
2. Siblings of mentally disabled face own lifelong challenges, according to researchers
3. Caltech researchers get first look at how groups of cells coordinate their movements
4. Computation and genomics data drive bacterial research into new golden age
5. Leeds research points to new therapy for hepatitis C treatment
6. Properties of unusual virus revealed in research
7. U of Minnesota researcher finds link between aggression, status and sex
8. Researchers study virus with unusual properties
9. Dune and dirty: Hurricane teaches lessons through ecosystem research
10. Key to curing obesity may lie in worms that destroy their own fat: McGill researchers
11. Massague honored with inaugural AACR Distinguished Leadership Award in Breast Cancer Research
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New research shows how gene function drives natural selection in important class of genetic elements
(Date:10/15/2014)... a non-traditional biophysics textbook and it describes how life ... of discovery into biological systems and provides an understanding ... is about how our genes make proteins that control ... cells in an organism. It quantifies the principles of ... be found on both large and small scales. The ...
(Date:10/15/2014)... Fred Alt will be awarded the 44th Rosenstiel Award ... for his pioneering research exploring the mechanisms of genomic ... cancer cells. Alt is the second alumnus to win ... Nobel Prize in 2003. , Alt is the Charles ... at Harvard Medical School and an investigator at the ...
(Date:10/14/2014)... have sequenced the house fly genome for the first ... from an insect that thrives in pathogen-rich dung piles ... in the journal Genome Biology , will increase ... how flies quickly adapt to resist insecticides, which could ... (Musca domestica) carry and transmit more than 100 human ...
Breaking Biology News(10 mins):New book about life as seen from physics 2Brandeis awards 44th Rosenstiel Award to pioneering geneticist Fred Alt 2House fly genome reveals expanded immune system 2
... of American Societies for Experimental Biology (FASEB) announces ... Conference (SRC): Matricellular Proteins in Development, Health, and ... extracellular matrix (ECM) are the basis for multi-cellular ... in all metazoan organisms. Structural ECM components such ...
... Societies for Experimental Biology (FASEB) announces the opening ... Mechanisms in Plant Development Conference. The 2013 ... and unique scientific conference where the intersections of ... through formal talks, poster sessions, and intensive scientific ...
... Two wasp species , Calymmochilus dispar and ... on ant-eating spiders in a study published in the ... spider, Zodarion styliferum , belongs to the largest genus ... and North Africa, significantly with at least 35 species reported ...
Cached Biology News:FASEB SRC announces conference: Matricellular Proteins in Development, Health, and Disease 2Survival of the fittest: Predator wasps breed at the expense of spider juveniles 2
(Date:10/19/2014)... NextCODE Health, which enables clinicians and researchers to ... today announced the launch of its new genomic data analysis ... American Society of Human Genetics (ASHG) annual meeting in ... and apply for free beta access, visit www.nextcode.com . ... be viewed here . The Exchange: ...
(Date:10/19/2014)... October 19, 2014 The report "Chocolate, ... Share, Trade, Prices, Geography Trend and Forecast (2011 - ... category, and geography and studies the major market drivers, ... America, Europe, and Asia. , The global chocolate market ... $98.3 billion in 2016 at an estimated CAGR of ...
(Date:10/18/2014)... October 19, 2014 The “Human ... Acting, Intermediate Acting, Premixed), Modern Human Insulin (Rapid ... Levemir, NovoRapid, Novomix, Tresiba, Others) - Forecast to ... drivers, restraints, challenges, opportunities, current market trends, and ... with the estimates and forecasts of the revenue ...
(Date:10/18/2014)... The Asia-Pacific hardware encryption display market report defines and ... forecast of revenue. This market was valued $5,154.0 million ... by 2018, at a CAGR of 58.4% from 2013 ... Asia-Pacific hardware encryption market report, to get an idea ... glimpse of the segmentation of the market, and is ...
Breaking Biology Technology:The NextCODE Exchange: The first global, real-time system for sharing full-resolution genomic data 2The NextCODE Exchange: The first global, real-time system for sharing full-resolution genomic data 3Chocolate Market Projected To Reach $98.3 Billion by 2016 - New Report by MarketsandMarkets 2Chocolate Market Projected To Reach $98.3 Billion by 2016 - New Report by MarketsandMarkets 3Chocolate Market Projected To Reach $98.3 Billion by 2016 - New Report by MarketsandMarkets 4Medical Human Insulin Market Is Expected to Reach $42 billion by 2019 - New Research Report by MarketsandMarkets 2Medical Human Insulin Market Is Expected to Reach $42 billion by 2019 - New Research Report by MarketsandMarkets 3Medical Human Insulin Market Is Expected to Reach $42 billion by 2019 - New Research Report by MarketsandMarkets 4Medical Human Insulin Market Is Expected to Reach $42 billion by 2019 - New Research Report by MarketsandMarkets 5The Asia-Pacific hardware encryption display market is expected to reach $51,362.6 million by 2018 - New Report by MicroMarket Monitor 2The Asia-Pacific hardware encryption display market is expected to reach $51,362.6 million by 2018 - New Report by MicroMarket Monitor 3
... busy at the BIO Chicago industry show this week. Rather ... pen or kangaroo lapel pin, he met with more than ... mostly in prearranged sessions designed to help attendees make the ... of NeoClone , which manufactures monoclonal antibodies. It was ...
... some prominent customers led to a new high in ... of 2006, the company reported Wednesday. , ,Specific figures ... quarter by exceeding expectations in license sales, services business, ... established in the fourth quarter of 2005. The company ...
... representatives from Japan, the second-largest biotech market in ... BIO convention, you might not think they would ... a show of Wisconsin's international partnerships in biotechnology, ... at the Japan international session. And speaker Tsuney ...
Cached Biology Technology:Partner program is highlight of BIO for Wisconsin firm 2Japanese delegates highlight Wisconsin at BIO Chicago 2Japanese delegates highlight Wisconsin at BIO Chicago 3
... Vector NTI Advance 9.1 ... and highly integrated application ... and molecular biology data ... readily available for export. ...
... 50mM Tris-HCl, pH 7.5, 0.1mM ... 1mM benzamidine, 0.1% 2-mercaptoethanol and ... Phosphatase 2A1) partially purified enzyme ... QSepharose,amino-hexyl agarose, Superdex 200, and ...
Whole blood is collected from mice (Swiss Webster, 8-10 weeks old,either sex) and processed within 45 minutes of collection. The complement is then filtered and pooled on ice, bottled and stored at -...
... vitro cell labeling mix, 92.5 ... solution stabilized with 0.1% 2-mercaptoethanol ... 3,4-dicarboxylic acid. *Amino acid mixture ... containing l-[35S]Methionine and l-[35S]Cysteine. * ...
Biology Products: