Navigation Links
New research on pre-eclampsia in mice may have important implications for humans
Date:7/27/2008

WHITE PLAIN, N.Y., JULY 27, 2008 In a new March of Dimes-funded study of pre-eclampsia, a serious and potentially deadly disorder that affects about 5 percent of pregnancies, researchers have found results in mice that may have important implications for diagnosis and treatment in humans.

Yang Xia, M.D., Ph.D., and Rodney E. Kellems, Ph.D., Department of Biochemistry and Molecular Biology; and Susan M. Ramin, M.D., Department of Obstetrics, Gynecology and Reproductive Science, all at the University of Texas-Houston Medical School, and colleagues report today in the journal Nature Medicine that they induced pre-eclampsia in mice by injecting them with certain human autoantibodies that have been found in women with pre-eclampsia. The mice showed multiple features of the disorder, including dangerously high blood pressure, protein in the urine, and placental abnormalities. Then the researchers gave the mice a substance that blocks the action of the autoantibodies; this prevented the development of pre-eclampsia.

The investigators say they demonstrated an important pathway of pre-eclampsia as well as a potential new approach to diagnosis and treatment.

Pre-eclampsia may require pre-term delivery (birth before 37 completed weeks gestation) to prevent severe complications to mother and baby, because delivery is the only cure for the disorder.

Preterm birth is a serious and costly health problem and the leading cause of death in the first month of life. More than a half million babies one out of every eight are born too soon each year in the United States. Babies who survive face the risk of serious life-long health problems including learning disabilities, cerebral palsy, blindness, hearing loss, and other chronic conditions including asthma. Even infants born just a few weeks too soon have a greater risk of breathing problems, feeding difficulties, temperature instability (hypothermia), jaundice and delayed brai
'/>"/>

Contact: Michele Kling
mkling@marchofdimes.com
914-997-4613
March of Dimes Foundation
Source:Eurekalert

Page: 1 2

Related biology news :

1. New study spotlights National Institutes of Health grant outcomes for clinical research
2. CMV infections affect more than just patients with compromised immune systems, researchers find
3. A new cellular pathway linked to cancer is identified by NYU researchers
4. Limiting fructose may boost weight loss, UT Southwestern researcher reports
5. Cancer drug delivery research at Case Western Reserve University cuts time from days to hours
6. Gladstone scientists create Wikipathways to foster research collaboration
7. MSU researcher uses grant to study little-known but largely useful microbes
8. Researchers find key to saving the worlds lakes
9. MIT researchers offer glimpse of rare mutant cells
10. UC San Diego researchers could help US military thwart explosive threats
11. Researcher helping to pioneer medical therapy for Fragile X Syndrome presents latest findings
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/6/2015)... Germany , August 6, 2015 /PRNewswire/ ... SensoMotoric Instruments (SMI) shows the world,s first ... based on Epson,s Moverio BT-200 see-through head mounted display ... new solution, unprecedented quality and efficiency is brought to ... displays. For the first time, professionals and researchers can ...
(Date:8/5/2015)... According to a new market research report, ... (BFSI, Airport, IT & Telecom, Utilities, Education, Defense & ... published by MarketsandMarkets, defines and segments the Physical Identity ... global PIAM Market is estimated to grow from $272.2 ... a CAGR of 14.9 % from 2014 to 2019. ...
(Date:8/5/2015)... , Aug. 5, 2015 The biosensors ... growth in applications, penetration into newer sectors, and development ... The global biosensors space has seen the entry of ... market so far. (Photo - http://photos.prnewswire.com/prnh/20150805/255570 ... Sullivan, Analysis of the Global Biosensors Market ...
Breaking Biology News(10 mins):SMI Shows First Eye Tracking Upgrade for Augmented Reality Glasses 2SMI Shows First Eye Tracking Upgrade for Augmented Reality Glasses 3Physical Identity and Access Management Market Worth $546.2 Million by 2019 2Physical Identity and Access Management Market Worth $546.2 Million by 2019 3Physical Identity and Access Management Market Worth $546.2 Million by 2019 4Innovative Biosensors Incite Use in Non-Traditional Applications 2Innovative Biosensors Incite Use in Non-Traditional Applications 3Innovative Biosensors Incite Use in Non-Traditional Applications 4
... Exercise is a magic drug for many people ... more widely prescribed by mental health care providers, according ... studies. "Exercise has been shown to have ... of the Anxiety Research and Treatment Program at Southern ...
... the Sahlgrenska Academy at the University of Gothenburg, Sweden, have ... fish that have been swimming in treated waste water. One ... in the blood of fish than in women who take ... to infertility in fish. The study is published in ...
... disease spinocerebellar ataxia type 5 (SCA5) damages nerve cells ... that the defective protein responsible for the disease cuts ... neurons. The study appears in the April 5 issue ... www.jcb.org ). SCA5 results from a faulty gene ...
Cached Biology News:Mental health providers should prescribe exercise more often for depression, anxiety 2Medicine residues may threaten fish reproduction 2Defective protein is a double hit for ataxia 2
(Date:8/26/2015)... ... 2015 , ... The 2015 Epigenomics & Metabolomics Meeting in Boston ... Asymmetrex to share the first report on progress with its crowdsourcing campaign designed ... tissue stem cells. , With a name like “H2A.Z asymmetry,” the new biomarker would ...
(Date:8/25/2015)... USA, and CARDIFF, UK (PRWEB) , ... August ... ... quickly and accurately determining whether breast tissue lesions are cancerous is described by ... by SPIE, the international society for optics and photonics. , In “ Breast ...
(Date:8/25/2015)... Human Longevity, Inc. (HLI), the genomics-based, technology-driven company, ... the company as Chief Operating Officer. Winham, who brings more ... experience, will report directly to HLI,s CEO, J. Craig ... as COO, Winham will be responsible for managing all HLI ... facility operations. HLI currently has three locations in ...
(Date:8/25/2015)... CA (PRWEB) , ... August ... ... premier developer of build-to-order, independent blade-based and rackmount computing infrastructure, today announced ... workstation rackmount offering, the RM1630DX. The latest system boasts two distinct, individually ...
Breaking Biology Technology:Asymmetrex Reports Positive Indicators for Crowdsourcing Campaign to Evaluate New Biomarker for Counting Adult Tissue Stem Cells for the First Time 2Asymmetrex Reports Positive Indicators for Crowdsourcing Campaign to Evaluate New Biomarker for Counting Adult Tissue Stem Cells for the First Time 3Asymmetrex Reports Positive Indicators for Crowdsourcing Campaign to Evaluate New Biomarker for Counting Adult Tissue Stem Cells for the First Time 4New Optical Method Promises Faster, More Accurate Diagnosis of Breast Cancer 2New Optical Method Promises Faster, More Accurate Diagnosis of Breast Cancer 3New Optical Method Promises Faster, More Accurate Diagnosis of Breast Cancer 4Human Longevity, Inc. Hires Life Sciences Leader, Mark Winham, as Chief Operating Officer 2Cirrascale® Announces Next Generation High Density, Two-in-One GPU Rackmount Offering Perfect for High Performance Remote Workstations 2Cirrascale® Announces Next Generation High Density, Two-in-One GPU Rackmount Offering Perfect for High Performance Remote Workstations 3
... A Night at the Museum to be held April ... The West Michigan Science,& Technology Initiative (WMSTI) is accepting ... Life Science Business,Showcase, Night at the Museum, to be ... at the Museum is seeking regional exhibitors from across ...
... build infrastructure, education and ... in Southern Spain, SOMERVILLE, Mass., Feb. 19 Spotfire, ... announced that the,company is joining forces for the development of ... a provider of,state-of-the-art software solutions for data management and data ...
... BEIJING, Feb. 19 /Xinhua-PRNewswire/ -- Sinovac Biotech Ltd. (Amex:,SVA), ... it,will hold its 2007 Annual Meeting of Shareholders on ... meeting will be held concurrently at,No. 39 Shangdi Xi ... Temple,Street, St. John,s, Antigua. All shareholders of record as ...
Cached Biology Technology:West Michigan Science & Technology Initiative Seeks Exhibitors for Annual Life Science Showcase 2TIBCO Spotfire and Integromics Partner on Development of Genomics Platform for Province of Andalusia 2TIBCO Spotfire and Integromics Partner on Development of Genomics Platform for Province of Andalusia 3TIBCO Spotfire and Integromics Partner on Development of Genomics Platform for Province of Andalusia 4Sinovac Biotech Ltd. Schedules 2007 Annual Meeting of Shareholders 2
Component in MasterPure™ Purification Kits...
...
Tris-EDTA Buffer Solution, 1X, pH 8.0, sterile...
Human Cell Line Slides...
Biology Products: