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New research may aid treatment of multiple myeloma patients
Date:1/23/2013

Center at GW, will be to translate the laboratory findings to the clinic. This work, which will be carried out in collaboration with Imad Tabbara, M.D., professor of medicine at GW SMHS, will involve screening multiple myeloma patients to determine whether the CDy1 assay can help guide treatment decisions or predict which patients will respond better to carfilzomib.

"I first became interested in this subject as a graduate student at the Ontario Cancer Institute in the early 1980's," said Hawley. "However, I became disheartened as a principal investigator in the late 1990's when we were unable to cure the disease in a mouse model using cutting-edge cancer gene therapy, and I stopped working in this area. Despite recent therapeutic advances, multiple myeloma remains incurable. About a year and a half ago, I had a conversation with Robert Siegel, M.D., professor of medicine at GW SMHS and director of the Katzen Cancer Research Center, who encouraged me to enter the field again, and I am really happy that I did."

Hawley's team of researchers includes lead coauthors Teresa Hawley, B.S., director of the GW Flow Cytometry Core Facility, and Irene Riz, Ph.D., assistant research professor of anatomy and regenerative biology, along with Louis DePalma, M.D., professor of pathology and of anatomy and regenerative biology, and Weiqun Peng, Ph.D., associate professor of physics and of anatomy and regenerative biology, together with collaborators Jun Zhu, Ph.D., director of the DNA Sequencing and Computational Biology Core at the National Heart, Lung and Blood Institute of the National Institutes of Health, and Young-Tae Chang, Ph.D., head of the Laboratory of Bioimaging Probe Development at the National University of Singapore Agency for Science, Technology and Research.


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Contact: Lisa Anderson
lisama2@gwu.edu
202-994-3121
George Washington University
Source:Eurekalert

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