Navigation Links
New research helps explain how progesterone preventspreterm birth
Date:2/9/2011

SAN FRANCISCO, FEB. 10, 2011 -- Research presented today at the 31st Annual meeting of the Society for Maternal-Fetal Medicine (SMFM) -- The Pregnancy Meeting has found that three proteins known as XIAP, BID, and Bcl-2 are responsible in part for the success of progesterone treatments in the prevention of preterm labor. They may also play an important role in triggering normal labor.

The proteins prevent preterm birth by hindering apoptosis the normal, orderly death of cells -- in the fetal membranes. Stronger, thicker fetal membranes are less likely to rupture prematurely leading to premature delivery, according to the study led by Errol R. Norwitz, MD, PhD, Ob/Gyn-in-Chief at Tufts Medical Center and chairman of Obstetrics/Gynecology at Tufts University School of Medicine.

"Dr. Norwitz's research adds to our basic understanding of what triggers labor, how the fetal membranes rupture and the role progesterone plays," said Alan R. Fleischman, MD, medical director of the March of Dimes.

In the United States, more than half a million babies are born preterm each year. Preterm birth, before 37 weeks of pregnancy, is a serious health problem that costs the United States more than $26 billion annually. It is the leading cause of newborn death, and babies who survive often face the risk of lifetime health challenges. Even infants born just a few weeks early have higher rates of hospitalization and illness than full-term infants. The last few weeks of pregnancy are critical to a baby's health because many important organs, including the brain, are not completely developed until then.

Today's award-winning study, "Progesterone Inhibits Basal Apoptosis In Fetal Membranes By Altering Expression Of Both Pro- And Anti-Apoptotic Proteins," is the eighth study by SMFM members to be honored by the March of Dimes for innovative research focused on preventing premature birth. The research was supported in part by a March of Dimes grant. March of Dimes is conducting a national Prematurity Campaign aimed at using research and awareness to reduce the increasing rate of premature birth.


'/>"/>

Contact: Elizabeth Lynch
elynch@marchofdimes.com
914-997-4286
March of Dimes Foundation
Source:Eurekalert

Related biology news :

1. Wistar Institute researcher receives New Innovator award from NIH
2. NC State researchers get to root of parasite genome
3. White Mountain Research Station to host climate change conference
4. Stevens awarded $1M for advanced biofuels research
5. Researchers find animal with ability to survive climate change
6. Researchers find an essential gene for forming ears of corn
7. Researchers note differences between people and animals on calorie restriction
8. Researcher working on destruction of chemical weapons
9. Researchers study acoustic communication in deep-sea fish
10. Researchers discover that growing up too fast may mean dying young in honey bees
11. The Rett Syndrome Research Trust launches operations
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/2/2016)... 2016  BioMEMS devices deployed in hospitals ... medical screening and diagnostic applications, such as ... that facilitate and assure continuous monitoring without ... being bolstered through new opportunities offered by ... coupled with wireless connectivity and low power ...
(Date:2/2/2016)... VIEW, Calif. , Feb. 2, 2016 /PRNewswire/ ... retinopathy market, Frost & Sullivan recognizes US-based Intelligent ... America Frost & Sullivan Award for New Product ... provider in North America , ... in the rapidly growing diabetic retinopathy market. The ...
(Date:1/27/2016)... Ohio , Jan. 27, 2016  Rite Track, ... based in West Chester, Ohio ... award winning service staff, based in Austin, ... capacity and ability to provide modifications, installations and technical ... Dovalina , CEO of PLUS, commented, "PLUS has provided ...
Breaking Biology News(10 mins):
(Date:2/8/2016)... N.C. , Feb. 8, 2016 Novan, Inc. today ... Chairman of the Board of Directors of Novan. In addition, ... North Carolina . --> ... Company also announced that it received a total of $32.8 million ... 2015 from its private investor network originating throughout the Research Triangle ...
(Date:2/8/2016)... , Feb. 8, 2016  BioElectronics Corporation ... medical devices, announced today that it is responding ... proceedings from the Securities and Exchange Commission posted ... Staelin , Chairman of the Board of BioElectronics ... of Business Administration at The Fuqua School of ...
(Date:2/8/2016)... ... February 08, 2016 , ... ... range of loose, bulk foods at various stages of the production process. Despite ... to inspect large bulk products post packaging such as sacks of dry powders. ...
(Date:2/8/2016)... Inc. (NYSE MKT: NNVC) (the "Company"), a nanomedicine company developing anti-viral ... will present information about the company,s programs at the BIOCEO conference ... York City . --> --> ... EST. Registered attendees can request a one on one meeting through ... --> New York City . ...
Breaking Biology Technology: