Navigation Links
New research helps explain how progesterone preventspreterm birth
Date:2/9/2011

SAN FRANCISCO, FEB. 10, 2011 -- Research presented today at the 31st Annual meeting of the Society for Maternal-Fetal Medicine (SMFM) -- The Pregnancy Meeting has found that three proteins known as XIAP, BID, and Bcl-2 are responsible in part for the success of progesterone treatments in the prevention of preterm labor. They may also play an important role in triggering normal labor.

The proteins prevent preterm birth by hindering apoptosis the normal, orderly death of cells -- in the fetal membranes. Stronger, thicker fetal membranes are less likely to rupture prematurely leading to premature delivery, according to the study led by Errol R. Norwitz, MD, PhD, Ob/Gyn-in-Chief at Tufts Medical Center and chairman of Obstetrics/Gynecology at Tufts University School of Medicine.

"Dr. Norwitz's research adds to our basic understanding of what triggers labor, how the fetal membranes rupture and the role progesterone plays," said Alan R. Fleischman, MD, medical director of the March of Dimes.

In the United States, more than half a million babies are born preterm each year. Preterm birth, before 37 weeks of pregnancy, is a serious health problem that costs the United States more than $26 billion annually. It is the leading cause of newborn death, and babies who survive often face the risk of lifetime health challenges. Even infants born just a few weeks early have higher rates of hospitalization and illness than full-term infants. The last few weeks of pregnancy are critical to a baby's health because many important organs, including the brain, are not completely developed until then.

Today's award-winning study, "Progesterone Inhibits Basal Apoptosis In Fetal Membranes By Altering Expression Of Both Pro- And Anti-Apoptotic Proteins," is the eighth study by SMFM members to be honored by the March of Dimes for innovative research focused on preventing premature birth. The research was supported in part by a March of Dimes grant. March of Dimes is conducting a national Prematurity Campaign aimed at using research and awareness to reduce the increasing rate of premature birth.


'/>"/>

Contact: Elizabeth Lynch
elynch@marchofdimes.com
914-997-4286
March of Dimes Foundation
Source:Eurekalert

Related biology news :

1. Wistar Institute researcher receives New Innovator award from NIH
2. NC State researchers get to root of parasite genome
3. White Mountain Research Station to host climate change conference
4. Stevens awarded $1M for advanced biofuels research
5. Researchers find animal with ability to survive climate change
6. Researchers find an essential gene for forming ears of corn
7. Researchers note differences between people and animals on calorie restriction
8. Researcher working on destruction of chemical weapons
9. Researchers study acoustic communication in deep-sea fish
10. Researchers discover that growing up too fast may mean dying young in honey bees
11. The Rett Syndrome Research Trust launches operations
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/22/2017)... VILNIUS, Lithuania , March 21, 2017 /PRNewswire/ ... identification and object recognition technologies, today announced the ... development kit (SDK), which provides improved facial recognition ... safety cameras on a single computer. The new ... algorithms to improve accuracy, and it utilizes a ...
(Date:3/20/2017)... Germany , March 20, 2017 At this ... Hamburg -based biometrics manufacturer DERMALOG. The Chancellor came to the DERMALOG ... is this year,s CeBIT partner country. At the largest German ... biometrics in use: fingerprint, face and iris recognition as well as DERMALOG´s ... ...
(Date:3/13/2017)... Germany , March 13, 2017 Future of security: ... ... DERMALOGs Face Matching enables to match face ... forms the basis to identify individuals. (PRNewsFoto/Dermalog Identification Systems) ... DERMALOG,s "Face Matching" is the fastest software for biometric ...
Breaking Biology News(10 mins):
(Date:3/23/2017)... , March 23, 2017  SeraCare ... to global in vitro diagnostics manufacturers and ... the industry,s first multiplexed Inherited Cancer ... testing by next-generation sequencing (NGS). The Seraseq™ ... developed with input from industry experts to ...
(Date:3/23/2017)... March 23, 2017  BioPharmX Corporation (NYSE MKT: ... the dermatology market, today reported financial results for ... and will provide an update on the company,s ... "We are pleased to report that ... BioPharmX," said President Anja Krammer. "We achieved key ...
(Date:3/23/2017)... , March 23, 2017 Kineta, Inc., ... of novel therapies in immuno-oncology, today announced the ... small molecule compounds that activate interferon response factor ... and demonstrate immune-mediated tumor regression in a murine ... study who demonstrated complete tumor regression to initial ...
(Date:3/23/2017)... ALBANY, New York , March 23, 2017 ... animal blood plasma products and derivatives market is fragmented due to the ... large players, such as Proliant, Thermo Fisher , and Sigma-Aldrich, ... clear leader, these three companies, collectively, held more than 76% of ... ...
Breaking Biology Technology: