Navigation Links
New research finds potential risk for millions in Africa believed resistant to vivax malaria
Date:11/15/2013

at encodes the parasite's Duffy-binding protein. Subsequent analysis of blood samples taken from infected subjects around the world revealed that duplication of the parasite's gene is occasionally found in other areas where vivax malaria is common. But the highest prevalence was in Madagascar. For example, less than 10 percent of the 33 samples tested from Cambodia had the duplicate gene, while it was found in over 50 percent of the 189 samples taken from Madagascar.

"It was particularly striking that most of the parasites that contained the duplicate gene came from areas where we see the population divided between Duffy-positive and Duffy-negative individuals," Serre said.

The researchers believe one possibility is that in such split populations, the Duffy-positive individuals keep parasites circulating in their communities, allowing them to frequently attempt to infect individuals who are Duffy-negative. Such repeated encounters, they say, increase the chances that a P. vivax parasite could develop a new way to penetrate red blood cells.

In Cambodia, Evidence of a New "Invasion Mechanism"

In the second study, the researchers analyzed the genome of a P. vivax parasite from Cambodia. They found a previously unknown gene that "harbors all the key features" of an "invasion protein" for gaining access to red blood cells. For example, the protein expressed by this gene is similar to proteins used by other Plasmodium parasites, including P. falciparum to cause infections.

Subsequent investigation found that this new gene is widely present in contemporary vivax parasites around the world, but with a notable exception: it is not found in the vivax parasite sequenced in 2008 that has been used by malaria scientists as the "reference" genome for studying the genetics of the parasite.

The ASTMH Annual Meeting is the premier international gathering for those working in malaria, note
'/>"/>

Contact: Preeti Singh
psingh@burnesscommunications.com
301-280-5722

Bridget DeSimone
bdesimone@burnesscommunications.com
301.280.5735

American Society of Tropical Medicine and Hygiene
Source:Eurekalert


Page: 1 2 3 4

Related biology news :

1. Northeastern researchers have discovered a new treatment to cure MRSA infection
2. Novel aspects of histamine research discussed in Versita open access book
3. Danish researchers predict risk of valvular heart disease
4. Researcher finds potential new use for old drugs
5. Using morphine after abdominal surgery may prolong pain, CU-Boulder researchers find
6. Wayne State researchers discover specific inhibitor for rheumatoid arthritis treatment
7. Protein illustrates muscle damage: McMaster researchers
8. Mainz University collaborates with 3 Chinese universities in research and teaching
9. F1000Research launch data plotting tool
10. Research reveals new understanding, warning signs, and potential treatments for multiple sclerosis
11. Research by Saint Louis University scientists offers way to disrupt fibrosis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/12/2015)... -- IriTech, a leading iris based identity management technology ... Design Network, announced today that the Chief Minister ... MK2120U device during a launching event of Andhra Pradesh ... The iris scanner is manufactured by U.S. based ... India through its Indian partner, Biometronic Technology, ...
(Date:3/11/2015)... 2015 Research and Markets ( http://www.researchandmarkets.com/research/3p32qm/access_control ... Control Market by Product, Application & By Geography - ... their offering. , This report predicts that ... billion by 2020, with an estimated CAGR of 10.6%. ... products types such as contact cards & readers, contactless ...
(Date:3/10/2015)... , March 10, 2015   Tute Genomics ... has been selected by next-generation sequencing company PrimBio ... whole exome and targeted gene panel interpretation. ... has adopted the most current technologies to support the ... research. The company offers two types of exome sequencing ...
Breaking Biology News(10 mins):Indian States See IriTech's Scanner Bolstering Efficiency of Authentication for Aadhaar 2Indian States See IriTech's Scanner Bolstering Efficiency of Authentication for Aadhaar 3Global Access Control (Cards & Readers, Biometrics, Controllers, Management Software) Market 2015-2020 - Analysis of the $10 Billion Market 2PrimBio Research Selects Tute as Whole Exome Analysis Provider, Creating Integrated, End-to-End Solution for Next-Generation Sequencing & Data Analysis 2PrimBio Research Selects Tute as Whole Exome Analysis Provider, Creating Integrated, End-to-End Solution for Next-Generation Sequencing & Data Analysis 3
... Calif. Stem cell research at the University of California, ... of a new Stem Cell Core Facility (SCCF) a ... stem cell research that ordinarily would not be available in ... Keen Hall, had its grand opening on Friday, Jan. 29. ...
... The Translational Genomics Research Institute (TGen) and Horizon ... for use in TGen,s cancer research. A research-collaboration ... Horizon,s GENESIS and X-MAN technologies to accelerate the search ... could provide patients with more effective treatments. Dr. ...
... researchers and their colleagues in Japan are conducting research that ... moleculesa necessary step if man someday hopes to build molecular ... scales. Dr. Eric Blough, a member of the ... of Biological Sciences, said his group has shown how bionanomotors ...
Cached Biology News:UC Riverside's new state-of-the-art technology to accelerate stem cell research 2TGen becomes center of excellence for Horizon Discovery's GENESIS and X-MAN technology 2Research at Marshall University may lead to new ways to transport and manipulate molecules 2Research at Marshall University may lead to new ways to transport and manipulate molecules 3
(Date:3/26/2015)... BOSTON , March 26, 2015 /PRNewswire/ ... ), a global clinical research organization ... signed a definitive agreement to acquire all ... India ("QSI"), a leading provider of specialized ... refers to the collection, detection, assessment, monitoring, ...
(Date:3/26/2015)... Ale Gicqueau, Founder and President of Clinovo, will co-present ... Technology, on “ Conducting Postmarket Registries - Rationale and ... and Exhibition on April 25th through April 28th in ... presentation, Ale Gicqueau and Victor Chen will discuss the ... requirements and resources to conduct the registry, as well ...
(Date:3/25/2015)... 26, 2015 Agnition announced today that ... American Farmer, airing for the first time at 7:30 ... American Farmer will explore the extremely important role soil ... with a patented Microbial Catalyst™ technology that enhances soil ... The segment will air again on April 28. , ...
(Date:3/25/2015)... March 25, 2015 The surging ... smartphones have fuelled social media growth, with over ... engaged in social networking. Insurance companies are making ... with clients and promote a diversity of their ... are increasingly exploiting social networking services as part ...
Breaking Biology Technology:PAREXEL Announces Execution of Definitive Agreement to Acquire Quantum Solutions India, Strengthening Leadership In Pharmacovigilance Services 2PAREXEL Announces Execution of Definitive Agreement to Acquire Quantum Solutions India, Strengthening Leadership In Pharmacovigilance Services 3PAREXEL Announces Execution of Definitive Agreement to Acquire Quantum Solutions India, Strengthening Leadership In Pharmacovigilance Services 4Clinovo Presents at ACRP 2015 in Salt Lake City, Utah on April 25th-28th 2Clinovo Presents at ACRP 2015 in Salt Lake City, Utah on April 25th-28th 3Agnition to be Featured In Upcoming Episode of American Farmer on RFD-TV 2Social Media Role in Global Insurance Industry Examined by Timetric in New Market Research Report Published at MarketPublishers.com 2Social Media Role in Global Insurance Industry Examined by Timetric in New Market Research Report Published at MarketPublishers.com 3
... SOUTH SAN FRANCISCO, Calif., Oct. 3 Cell,Genesys, Inc. ... MBChB, chief,medical officer of Cell Genesys, will present a ... at the BIO Investor Forum being,held in San Francisco, ... will be accessible through the,Investor Relations section of the ...
... Fully Automated, Portable Solution for In-Clinic and Out-Reach Influenza ... ... England, October 3 Enigma Diagnostics, the,life sciences company developing rapid ... European Commission,Framework 7 programme to the RANGER consortium. The award will ...
... to grow forests of tiny cylinders called carbon nanotubes ... flow of heat at a critical point where the ... The carpetlike growth of nanotubes has been shown to ... nanotube layer does not require elaborate clean-room environments, representing ...
Cached Biology Technology:Cell Genesys to Present at the BIO Investor Forum 2Enigma Diagnostics Announces a European Commission Award of EUR3 Million to Fund the Development of a Point of Care Platform for the Rapid Diagnosis of Influenza Infections 2Nanotube forests grown on silicon chips for future computers, electronics 2Nanotube forests grown on silicon chips for future computers, electronics 3
... Building on the ease of use and flexibility of ... Biosciences introduces the BDTM LSR II. The BD ... before in a benchtop analyzer. Free up your ... a UV laser to the BD LSR II. The ...
...
Fingerprinting II Informatix cluster analysis is an optional module that adds dendrogram and phylogenetic tree construction, cluster and group significance, and congruence of techniques functions to ...
... identification and library manager ... that adds capabilities for ... identification of unknowns against ... of the same taxon ...
Biology Products: