Navigation Links
New research finds potential risk for millions in Africa believed resistant to vivax malaria
Date:11/15/2013

Zimmerman's colleague, David Serre, PhD, of the Cleveland Clinic's Genomic Medicine Institute, said that while there is not yet enough evidence to conclude that the P. vivax parasite is gaining virulence, "we think the genetic mechanisms we have uncovered could dramatically change our understanding of this very important form of malaria that doesn't get as much attention as falciparum malaria, even though it causes severe disease and may be more deadly than many think."

Also, vivax malaria is in one respect more dangerous than falciparum malaria: the P. vivax parasite has the ability to "hide" in the liver and re-emerge multiple times in the bloodstream to cause relapse infections.

Kevin Baird, PhD, an expert in vivax malaria at the Eijkman-Oxford Clinical Research Unit in Indonesia, said the "expanding reports of vivax malaria in Duffy-negative individuals are alarming." But Baird, who was leading discussions at the ASTMH Annual Meeting on improving vivax malaria diagnostics and treatment, said it remains to be seen whether "this is an emerging problem or a low-probability event that has always been around." He also noted that research identifying infections in Duffy-negative individuals indicates that, overall, people who lack the protein still seem less likely to get vivax malaria, even if they may not be fully protected.

In Madagascar, a Surge in Duffy-Negative Infections

Zimmerman and his colleagues looked for biological mechanisms that might explain "Duffy-negative infections" by sequencing the genome of several P. vivax parasites, including parasites gathered in Madagascar. Madagascar has been of particular interest, they said, because infections in Duffy-negative individuals have been occurring there at a comparatively high rate.

In the study published today, they report finding something that had not been seen before in P. vivax parasites: two copies of the gene th
'/>"/>

Contact: Preeti Singh
psingh@burnesscommunications.com
301-280-5722

Bridget DeSimone
bdesimone@burnesscommunications.com
301.280.5735

American Society of Tropical Medicine and Hygiene
Source:Eurekalert


Page: 1 2 3 4

Related biology news :

1. Northeastern researchers have discovered a new treatment to cure MRSA infection
2. Novel aspects of histamine research discussed in Versita open access book
3. Danish researchers predict risk of valvular heart disease
4. Researcher finds potential new use for old drugs
5. Using morphine after abdominal surgery may prolong pain, CU-Boulder researchers find
6. Wayne State researchers discover specific inhibitor for rheumatoid arthritis treatment
7. Protein illustrates muscle damage: McMaster researchers
8. Mainz University collaborates with 3 Chinese universities in research and teaching
9. F1000Research launch data plotting tool
10. Research reveals new understanding, warning signs, and potential treatments for multiple sclerosis
11. Research by Saint Louis University scientists offers way to disrupt fibrosis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/22/2014)... 21, 2014 Diabetes affects nearly 10 percent ... of diabetics: constant finger pricking to test blood ... Biology reports the development of a protein that ... results for diabetes patients. In the American Chemical ... Ph.D., shows off her "designer protein" that could ...
(Date:8/22/2014)... release is available in German . ... substances, in PCFs proteins are fixated in a way ... crystals. Next, the HZB and Fudan University researchers are ... as functional materials. Their findings are being published today ... 10.1038/ncomms5634). , Proteins are sensitive molecules. Everyone knows that ...
(Date:8/22/2014)... In 2015, American consumers will finally be able to ... Although touted as zero-emissions vehicles, most of the cars ... fossil fuel that contributes to global warming. , Now ... device that uses an ordinary AAA battery to produce ... electric current through two electrodes that split liquid water ...
Breaking Biology News(10 mins):Proteins: New class of materials discovered 2Stanford scientists develop a water splitter that runs on an ordinary AAA battery 2Stanford scientists develop a water splitter that runs on an ordinary AAA battery 3
... have created an application that enables cell phones and ... English speakers and could be used for people who ... type in the menu listing and the application translates ... "Mimi" Boutin, an associate professor in Purdue University,s School ...
... Belmont, MAA new study from McLean Hospital/Harvard Medical ... genetic research drawing correlations between specific genes, environmental ... the development of some psychiatric illnesses needs additional ... , McLean Hospital investigator Laramie Duncan, PhD, ...
... faster than ever and not only when it ... bodies are reaching puberty at an increasingly earlier age, ... adult lives. That,s bad news, according to Tel Aviv ... Hyperostosis Frontalis Interna (HFI), a hormonal condition once typically ...
Cached Biology News:New translator app makes sense of foreign-language food menus 2New translator app makes sense of foreign-language food menus 3McLean: Improvements are needed for accuracy in gene-by-environment interaction studies 2McLean: Improvements are needed for accuracy in gene-by-environment interaction studies 3Is estrogen going to your head? 2Is estrogen going to your head? 3
(Date:8/21/2014)... Aug. 21, 2014 OTC Markets ... Inc., a biotechnology company, on its approval to ... traded on OTCQX®, the best marketplace for established ... Group. Logo - http://photos.prnewswire.com/prnh/20110118/MM31963LOGO ... successful execution of its growth strategy and achievement ...
(Date:8/21/2014)... 21, 2014 Pursuit Solutions ( ... technology and services for Life Sciences sales and ... Use of New Commercial Sales Models” by Peter ... , The article examines some innovative models used ... being tested in the pharmaceutical market. Robinson grades ...
(Date:8/21/2014)... 21, 2014 SoundConnect , ... recognized as one of the nation’s Fastest Growing ... for the 2nd consecutive year. Inc. magazine today ... Inc. 500|5000, an exclusive ranking of the nation's ... comprehensive look at the most important segment of ...
(Date:8/20/2014)... to biotechnology firms has revealed early bottlenecks on ... the researchers suggest that better communication of basic ... to faster commercialization down the road. , Biopharmaceutical ... university laboratories and licensed to biotechnology firms. Bottlenecks ... a high failure rate. But a new study ...
Breaking Biology Technology:OTC Markets Group Congratulates Immune Pharmaceuticals on NASDAQ Listing 2Pursuit's Peter Robinson Publishes "Grading Pharma's Use of New Commercial Sales Models" 2SoundConnect Returns on Inc. 5000 List of Fastest Growing Companies 2SoundConnect Returns on Inc. 5000 List of Fastest Growing Companies 3Early bottlenecks in developing biopharmaceutical products delay commercialization 2Early bottlenecks in developing biopharmaceutical products delay commercialization 3
... SAN DIEGO, Feb. 27 Anadys Pharmaceuticals,Inc. (Nasdaq: ... the Susquehanna,Second Annual SIGnificant Options in Healthcare Conference on ... PST). The conference is being,held at the W Hotel ... Chief Executive Officer of Anadys,Pharmaceuticals, Inc., will present an ...
... researchers at North Carolina State University have demonstrated ... or chemically different so-called Janus particles ... electrical field is applied to liquid surrounding the ... in the Feb. 8, 2008, edition of Physical ...
... of Stock Repurchase Program -, LIONVILLE, Pa., Feb. 27 ... that its Board of Directors,approved a second quarter 2008 cash ... May 7, 2008 to shareholders of record on April 23,2008., ... shares of,its common stock at an average price of $40.23 ...
Cached Biology Technology:Anadys Pharmaceuticals to Present at the Susquehanna SIGnificant Options in Healthcare Conference 2'2-faced' particles act like tiny submarines 2
... HT is designed for extended ... HT is ideal for applications ... primer extension assays. iEMS Incubator/Shaker ... one-cabinet model, allowing the capacity ...
The iEMS Incubator/Shaker is a high performance microplate incubator and orbital shaker. Its superior temperature control and efficient orbital shaking reduce incubation times. -...
The iEMS Incubator/Shaker is a high performance microplate incubator and orbital shaker. Its superior temperature control and efficient orbital shaking reduce incubation times. It can incubate up to ...
... Anti-Reverse Cap Analog (ARCA) is a modified ... group (closer to m7G) is replaced with ... polymerase can only initiate transcription with the ... in the forward orientation. As a result, ...
Biology Products: