Navigation Links
New research findings can improve avian flu surveillance programs
Date:1/12/2010

Genetic analyses of avian influenza in wild birds can help pinpoint likely carrier species and geographic hot spots where Eurasian viruses would be most likely to enter North America, according to new U.S. Geological Survey research.

Persistence of the highly pathogenic avian influenza H5N1 (HPAI H5N1) virus in Eurasia and Africa, and concerns that the virus might be transported among continents by migratory birds has resulted in global surveillance programs. In the United States, state and federal agencies tested more than 326,000 wild bird samples from across the country from 2005 to 2008.

The new work by USGS has nationwide importance because it offers a method for avian influenza surveillance programs to target their efforts for the right species and in the best locations.

In the study, USGS scientists conducted the first-ever survey of avian influenza gene variation in a single host species -- the northern pintail -- at each end of the bird's migratory flyway in North America: Alaska and California. These birds migrate between North America and Eurasia and in Japan and China have been known to occur in outbreak areas of HPAI H5N1.

The researchers discovered that some avian influenza viruses recovered from the North American pintails contain genes that are more closely related to influenza viruses in Eurasia, and that the greatest number of these genes occurred in pintail viruses from Alaska. In contrast, northern pintails sampled on their main wintering areas in California had few Eurasian virus genes.

The researchers speculate that Euasian flu genes become less prevalent as birds migrate southward in fall due to rapid mutation and reassortment, common to influenza viruses, and dilution by existing North American flu viruses. Reassortment, a shuffling process among viruses that infect the same host, occurs in all types of influenza A viruses, including H1N1 and H5N1.

"Our research demonstrates a genetically based technique for prioritizing wild bird species that are targeted for surveillance," said Dr. John Pearce, a USGS scientist and lead author of the study. "Refining the list of priority species for surveillance by this method can reduce time and effort involved in surveillance sampling and is needed not only for Alaska, but also for those species along the North

Atlantic coast of North America that may engage in transcontinental migrations, such as shorebirds and gulls," Pearce said.

With few exceptions, genetic evidence for transcontinental avian influenza virus exchange in North America has come from coastal regions closest to Europe or Asia Alaska and the North Atlantic.

These areas, said Pearce, probably represent the first or primary areas of contact for foreign viruses, yet only about a third of birds tested for HPAI H5N1 in the United States so far have been from these regions.

"Based on this new genetic evidence, one possible new strategy would be to target surveillance efforts on species in these coastal regions that are geographically closer to current sources of the highly pathogenic H5N1 virus," Pearce said. "If there is no evidence of transcontinental avian influenza virus gene exchange for a certain species or regional pathway, then those species and areas could be deemphasized in future surveillance programs."


'/>"/>

Contact: Catherine Puckett
cpuckett@usgs.gov
352-264-3532
United States Geological Survey
Source:Eurekalert

Related biology news :

1. Research shows skeleton to be endocrine organ
2. Newly created cancer stem cells could aid breast cancer research
3. Dominant cholesterol-metabolism ideas challenged by new research
4. Researchers identify proteins involved in new neurodegenerative syndrome
5. Texas researchers and educators head for Antarctica
6. MGH researchers describe new way to identify, evolve novel enzymes
7. University of Pennsylvania researchers develop formula to gauge risk of disease clusters
8. University of Oregon researcher finds that on waters surface, nitric acid is not so tough
9. U of MN researchers discover noninvasive diagnostic tool for brain diseases
10. U of Minnesota researchers discover noninvasive diagnostic tool for brain diseases
11. Story ideas from the Journal of Lipid Research
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/28/2017)... March 28, 2017 The report ... (Camera, Monitors, Servers, Storage Devices), Software (Video Analytics, VMS), ... - Global Forecast to 2022", published by MarketsandMarkets, the ... and is projected to reach USD 75.64 Billion by ... 2022. The base year considered for the study is ...
(Date:3/23/2017)... Research and Markets has announced the addition of the ... to 2025" report to their offering. ... The Global Vehicle Anti-Theft System Market ... the next decade to reach approximately $14.21 billion by 2025. ... for all the given segments on global as well as regional ...
(Date:3/20/2017)... 20, 2017 PMD Healthcare announces the release ... Wellness Management System (WMS), a remote, real-time lung health ... PMD Healthcare is a Medical Device, Digital Health, and ... to creating innovative solutions that empower people to improve ... focus, PMD developed the first ever personal spirometer, Spiro ...
Breaking Biology News(10 mins):
(Date:4/25/2017)... ... April 25, 2017 , ... Leaders of Quorum Review IRB ... featured in multiple sessions at this week’s Association of Clinical Research Professionals (ACRP) ... practices in clinical research. , "We are excited to present subject matter expertise on ...
(Date:4/24/2017)...  Dante Labs announced today the offer of whole genome ... While American individuals have been able to access WGS at ... WGS below EUR 1,000. The sequencing includes bioinformatics ... to make informed decisions about disease monitoring, prevention, nutrition, exercise, ... ...
(Date:4/21/2017)... ... April 21, 2017 , ... Having worked on the design of the ... to introduce it to top lab design architects from around the country at the ... of Industrial Design and Engineering Greg Casey will be at the show, where they ...
(Date:4/21/2017)... BELLINGHAM, Washington, USA (PRWEB) , ... April 21, ... ... for sensing, imaging, and related applications were the focus of researchers, engineers, product ... Sensing 2017 in Anaheim. , Sponsored by SPIE, the international society ...
Breaking Biology Technology: