Navigation Links
New research findings can improve avian flu surveillance programs
Date:1/12/2010

Genetic analyses of avian influenza in wild birds can help pinpoint likely carrier species and geographic hot spots where Eurasian viruses would be most likely to enter North America, according to new U.S. Geological Survey research.

Persistence of the highly pathogenic avian influenza H5N1 (HPAI H5N1) virus in Eurasia and Africa, and concerns that the virus might be transported among continents by migratory birds has resulted in global surveillance programs. In the United States, state and federal agencies tested more than 326,000 wild bird samples from across the country from 2005 to 2008.

The new work by USGS has nationwide importance because it offers a method for avian influenza surveillance programs to target their efforts for the right species and in the best locations.

In the study, USGS scientists conducted the first-ever survey of avian influenza gene variation in a single host species -- the northern pintail -- at each end of the bird's migratory flyway in North America: Alaska and California. These birds migrate between North America and Eurasia and in Japan and China have been known to occur in outbreak areas of HPAI H5N1.

The researchers discovered that some avian influenza viruses recovered from the North American pintails contain genes that are more closely related to influenza viruses in Eurasia, and that the greatest number of these genes occurred in pintail viruses from Alaska. In contrast, northern pintails sampled on their main wintering areas in California had few Eurasian virus genes.

The researchers speculate that Euasian flu genes become less prevalent as birds migrate southward in fall due to rapid mutation and reassortment, common to influenza viruses, and dilution by existing North American flu viruses. Reassortment, a shuffling process among viruses that infect the same host, occurs in all types of influenza A viruses, including H1N1 and H5N1.

"Our research demonstrates a genetically based technique for prioritizing wild bird species that are targeted for surveillance," said Dr. John Pearce, a USGS scientist and lead author of the study. "Refining the list of priority species for surveillance by this method can reduce time and effort involved in surveillance sampling and is needed not only for Alaska, but also for those species along the North

Atlantic coast of North America that may engage in transcontinental migrations, such as shorebirds and gulls," Pearce said.

With few exceptions, genetic evidence for transcontinental avian influenza virus exchange in North America has come from coastal regions closest to Europe or Asia Alaska and the North Atlantic.

These areas, said Pearce, probably represent the first or primary areas of contact for foreign viruses, yet only about a third of birds tested for HPAI H5N1 in the United States so far have been from these regions.

"Based on this new genetic evidence, one possible new strategy would be to target surveillance efforts on species in these coastal regions that are geographically closer to current sources of the highly pathogenic H5N1 virus," Pearce said. "If there is no evidence of transcontinental avian influenza virus gene exchange for a certain species or regional pathway, then those species and areas could be deemphasized in future surveillance programs."


'/>"/>

Contact: Catherine Puckett
cpuckett@usgs.gov
352-264-3532
United States Geological Survey
Source:Eurekalert

Related biology news :

1. Research shows skeleton to be endocrine organ
2. Newly created cancer stem cells could aid breast cancer research
3. Dominant cholesterol-metabolism ideas challenged by new research
4. Researchers identify proteins involved in new neurodegenerative syndrome
5. Texas researchers and educators head for Antarctica
6. MGH researchers describe new way to identify, evolve novel enzymes
7. University of Pennsylvania researchers develop formula to gauge risk of disease clusters
8. University of Oregon researcher finds that on waters surface, nitric acid is not so tough
9. U of MN researchers discover noninvasive diagnostic tool for brain diseases
10. U of Minnesota researchers discover noninvasive diagnostic tool for brain diseases
11. Story ideas from the Journal of Lipid Research
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/30/2017)... , March 30, 2017 The research team ... for three-dimensional (3D) fingerprint identification by adopting ground breaking 3D fingerprint ... new realm of speed and accuracy for use in identification, crime ... affordable cost. ... A ...
(Date:3/29/2017)... , March 29, 2017  higi, the health IT ... North America , today announced a ... the acquisition of EveryMove. The new investment and acquisition ... of tools to transform population health activities through the ... data. higi collects and secures data today ...
(Date:3/27/2017)... CENTRE, N.Y. , March 27, 2017 /PRNewswire-USNewswire/ ... Healthcare Information and Management Systems Society (HIMSS) Analytics ... Outpatient EMR Adoption Model sm . In addition, ... 12% of U.S. hospitals using an electronic medical ... CHS for its high level of EMR usage ...
Breaking Biology News(10 mins):
(Date:10/10/2017)... Calif. , Oct. 10, 2017 SomaGenics ... from the NIH to develop RealSeq®-SC (Single Cell), expected ... for profiling small RNAs (including microRNAs) from single cells ... Program highlights the need to accelerate development of approaches ... "New techniques for measuring levels ...
(Date:10/9/2017)... ... ... The award-winning American Farmer television series will feature 3 Bar Biologics in an ... on RFD-TV. , With global population estimates nearing ten billion people by 2050, ... a growing nation. At the same time, many of our valuable resources are becoming ...
(Date:10/7/2017)... (PRWEB) , ... October 06, ... ... years’ experience providing advanced instruments and applications consulting for microscopy and surface ... expertise in application consulting, Nanoscience Analytical offers a broad range of contract ...
(Date:10/6/2017)... D.C. (PRWEB) , ... October 06, 2017 , ... ... will host a lunch discussion and webinar on INSIGhT, the first-ever adaptive clinical ... Principal Investigator, Dana-Farber Cancer Institute. The event is free and open to the ...
Breaking Biology Technology: