Navigation Links
New pathogen from pigs' stomach ulcers
Date:6/8/2008

Scientists have isolated a new bacterium in pigs' stomachs thanks to a pioneering technique, offering hope of new treatments to people who suffer with stomach ulcers, according to research published in the June issue of the International Journal of Systematic and Evolutionary Microbiology.

The bacterium that commonly causes stomach ulcers in humans is called Helicobacter pylori. Extensive research has been carried out on this bacterium and the two scientists who discovered it were awarded the Nobel Prize for Physiology and Medicine in 2005. However, in a small percentage of biopsies a similar but previously unidentified bacterium is present. Numerous research papers have described failed attempts to culture this microbe in the laboratory since it was first observed in 1990. Now, scientists from Belgium have succeeded.

"We have developed a new method to cultivate these bacteria and can now study their main characteristics and virulence properties," said Professor Dr Freddy Haesebrouck from Gent University in Belgium. The researchers had to recreate aspects of the bacterium's natural habitat, the stomach. They used acid, which kills other microbes but is needed for these bacteria to grow. Charcoal was used to remove substances that are toxic to the stomach bacterium. Genetic analysis revealed that it is a new species related to the common stomach ulcer bacterium Helicobacter pylori. Its name, Helicobacter suis, comes from the Latin for "of the pig".

H. suis has been associated with stomach ulcers in pigs, which may cause sudden death: a big problem for farmers. "The economic losses for the pork industry and the risk of the bacteria infecting humans justify the need for further research," said Dr Margo Baele from Gent University in Belgium. "Data shows that people in close contact with pigs have a higher risk of infection; this suggests H. suis is a zoonotic agent, capable of being transmitted from animals to humans."

"We know very little about how the bacterium infects humans and pigs and how it causes disease. Thanks to this research, pure isolates of H. suis are now available, bringing new perspectives to the study of this organism and its interaction with the host," says Professor Dr Freddy Haesebrouck.

The new technique will allow researchers to determine whether the bacterium is resistant to antibiotics. This will lead to better treatment strategies, both in pigs and humans. The researchers hope it may also result in the development of an effective vaccine.


'/>"/>
Contact: Lucy Goodchild
l.goodchild@sgm.ac.uk
44-118-988-1843
Society for General Microbiology
Source:Eurekalert

Related biology news :

1. Understanding, combating foodborne pathogens E. coli 0157 and salmonella
2. New magnetic separation technique might detect multiple pathogens at once
3. New system would use rotating magnetic field to detect pathogens
4. K-State specialist in tick-borne pathogens receives $1.8 million grant
5. Pathogens use previously undescribed mechanism to sabotage host immune system
6. Can interacting pathogens explain disease patterns?
7. Breakthrough research turns the tide on water-borne pathogen
8. Tomato pathogen genome may offer clues about bacterial evolution at dawn of agriculture
9. Technology uses live cells to detect food-borne pathogens, toxins
10. Researcher discovers pathway plants use to fight back against pathogens
11. Tomato pathogen genome may offer clues about bacterial evolution
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/19/2016)... 18, 2016 Securus Technologies, a leading provider ... safety, investigation, corrections and monitoring, announced today that it ... to have an independent technology judge determine who has ... high tech/sophisticated telephone calling platform, and the best customer ... do most of what we do – which clearly ...
(Date:11/17/2016)... OF INDUSTRY, Calif. , Nov. 17, 2016  AIC announces that it has ... using NVMe storage servers in organizations that require high-performance scale-out plus high speed data transfer storage ... ... ... Setting up ...
(Date:11/15/2016)... 15, 2016  Synthetic Biologics, Inc. (NYSE MKT: ... on the gut microbiome, today announced the pricing ... of its common stock and warrants to purchase ... price to the public of $1.00 per share ... from the offering, excluding the proceeds, if any ...
Breaking Biology News(10 mins):
(Date:12/8/2016)... ... December 08, 2016 , ... KBioBox llc announced today ... demand KbioBox developed a sophisticated “3 click” gene dditing off target analysis program ... new website, https://www.kbiobox.com/ and powered by the company’s proprietary BioEngine. ...
(Date:12/8/2016)... Dec. 8, 2016  Soligenix, Inc. (OTCQB: SNGX) ... focused on developing and commercializing products to treat ... need, announced today the long-term follow-up data from ... a first-in-class Innate Defense Regulator (IDR), in the ... neck cancer patients undergoing chemoradiation therapy (CRT).  The ...
(Date:12/8/2016)... 2016 Eutilex Co. Ltd. today announced that ... Series A financing. This financing round included participation from ... SNU Bio Angel. This new funding brings the total ... $27.7M) since its founding in 2015. ... and commercialization of its immuno-oncology programs, expand its R&D ...
(Date:12/7/2016)... ... 07, 2016 , ... A new study published in the ... treated, advanced pancreatic cancer, liquid biopsies are not yet an adequate substitute for ... blood sampling may improve the value of a blood-based test.” The study was ...
Breaking Biology Technology: