Cardiovascular disease is the leading cause of death globally and a tremendous burden on the healthcare system. Better detection of hardening or clogging of arteries and other blood vessels before symptoms occur is needed. With funding from the National Institutes for Health (NIH), researchers from Virginia Tech and GE Global Research Center are developing novel cardiac computed tomography (CT) architectures and methods, including a newly patented approach to a long-standing challenge in local CT image reconstruction (Patent 7,697,658 "Interior Tomography and Instant Tomography by Reconstruction from Truncated Limited-angle Projection Data" issued April 13, 2010). The research team will also evaluate the performance of various cardiac CT system designs to determine the most promising designs and demonstrate their clinical feasibility and utility.
Better image quality at lower radiation dose is the immediate need being addressed by the research project led by Ge Wang, the Pritchard Professor and director of the Biomedical Imaging Division (www.imaging.sbes.vt.edu) of the Virginia Tech Wake Forest University School of Biomedical Engineering & Sciences (SBES), and Bruno De Man, a CT authority at GE Global Research Center.
Faster, dynamic imaging to capture the beating heart and algorithms or computations that can present the most exact images from X-ray projections are also among project goals. "Cardiac CT technology needs major improvements to capture a fast beating heart with better clarity at lower risk," said Wang.
In traditional X-ray CT imaging, data is recorded behind the patient. Everything is superimposed along the X-ray path through the patient. In other words, an X-ray projection of the heart includes the bone and muscle along the way to the detectors. With current CT, the X-rays probe the patient along multiple wide beams focused on the patient including a region of interest,
|Contact: Susan Trulove|