Navigation Links
New paper examines poison resistance in snakes around the world
Date:3/19/2012

A new study by University of Notre Dame biologist Michael Pfrender and a team of researchers from the University of Nevada-Reno, Utah State University and the University of Virginia suggests that snakes from different regions of the world have evolved a similar, remarkable resistance to a deadly neurotoxin.

The finding, which appeared in the Proceedings of the National Academy of Sciences, greatly increases scientists' understanding of the genetic basis of adaptation and is a model for understanding the limits to adaptation and the degree to which evolutionary responses are predictable.

Pfrender and colleagues found that species of snakes in North, Central and South America and Asia that are able to feed on amphibians that secrete a deadly neurotoxic poison, tetrodotoxin or TTX. These snakes have similar mutations in a key sodium-channel gene that makes them highly resistant to TTX. These mutations prevent TTX from blocking the sodium channels in muscle, which would otherwise immobilize the snakes by paralyzing nervous and muscle tissue.

"The key finding is that adaptive evolution is constrained by the functional properties of the genes involved in these evolutionary responses," Pfrender said. "While there are many possible mutations that can improve fitness, in this case resistance to the neurotoxin TTX, many of these mutations have a cost because they change the normal function of the genes. So, when we look at multiple species that have independently adapted to TTX, we see a very similar, and limited, set of mutations involved. The story is one of repeated evolutionary change that occurs through a limited set of changes at the molecular level."

The study stems from Pfrender's interest in understanding how organisms deal with environmental change through adaptive evolution.

"We would like to know what the underlying genetic mechanisms are, and what the limits are to these adaptive responses," he said. "Ultimately, we would lik
'/>"/>

Contact: Michael Pfrender
Michael.Pfrender.1@nd.edu
574-631-0591
University of Notre Dame
Source:Eurekalert

Page: 1 2

Related biology news :

1. New papers offer insights into process of malarial drug resistance
2. French scientist wins the Journal of Experimental Biology Outstanding Paper Prize
3. High school students paper published in prestigious college math journal
4. HSPD-24 White Paper Now Available From WCC Smart Search & Match
5. New paper offers key insights into how new species emerge
6. Researchers win award for best clinical paper in orthopedic physical therapy
7. GSA special paper presents new studies of Western US earth motion
8. Beetle shell inspires brilliant white paper
9. ADA releases updated position paper on vegetarian diets
10. ADA releases position paper on food and water safety
11. Lower-cost solar cells to be printed like newspaper, painted on rooftops
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/11/2015)... According to a ... Product (Cards and Readers, Biometrics, Controllers, Management Software), ... Healthcare, Education) and By Geography - Global Forecast and Analysis to ... Control Market is expected to reach $10.4 ... of 10.6% between 2014 and 2020. ...
(Date:2/5/2015)... 5, 2015  Marken is starting its 35 th ... launched a new marketing campaign to solidify its place ... new campaign focuses on First as a ... The first headline in the series, ... with its client,s priorities. Marken recognizes the need to ...
(Date:2/5/2015)... , January 28, 2015 ... Analysis, Size And Segment Forecasts To 2020 has Been ... IR camera market is expected to reach USD 5.10 ... Grand View Research, Inc. IR cameras help identify the ... are expected to witness surging demand in medical imaging ...
Breaking Biology News(10 mins):Access Control Market Worth $10.4 Billion by 2020 2Access Control Market Worth $10.4 Billion by 2020 3Access Control Market Worth $10.4 Billion by 2020 4Marken Launches New Patient-Centric Campaign 2IR Camera Market Worth $5.10 Billion By 2020: Grand View Research, Inc. 2IR Camera Market Worth $5.10 Billion By 2020: Grand View Research, Inc. 3
... How long your parents lived does not affect how long you ... determines how old you will get, reveals research from the University ... . It is often assumed that people with parents who ... a grand old age themselves. "But that,s just not true ...
... A team of applied physicists at Harvard,s School ... have demonstrated the formation of semipermeable vesicles from inorganic ... the journal Soft Matter, shows that clay ... complex organic molecules. The authors say the discovery ...
... contains antioxidants which may be beneficial to health. New research ... demonstrates that chocolate is a rich source of antioxidants ... When researchers at the Hershey Center for Health & ... powders they found that, gram per gram, there was more ...
Cached Biology News:Lifestyle affects life expectancy more than genetics 2Clay-armored bubbles may have formed first protocells 2
(Date:2/26/2015)... , Feb. 26, 2015  23andMe, the leading ... Kate Black as Privacy Officer and Corporate Counsel. ... state privacy laws as well as health care regulations. ... she will be responsible for reviewing, updating and enhancing ... the U.S. and abroad. She joined the company January ...
(Date:2/26/2015)... MENLO PARK, Calif. , Feb. 26, 2015 /PRNewswire/ ... has released the latest version of the Governance ... organizations accomplish governance, risk and compliance (GRC) tasks across ... has also been updated to help customers better align ... Organizations of the Treadway Commission ) requirements. In response ...
(Date:2/26/2015)... 2015  NuGene International, Inc. ("NuGene") (OTCQB: NUGN), ... and hair rejuvenation, has announced that it has ... for investor relations and strategic communications. ... and diversification strategies – and we need to ... stated Ali Kharazmi CEO of NuGene when announcing ...
(Date:2/26/2015)... Already well respected for accuracy, HEIDENHAIN ... its Length Gauge offerings with new variants of its ... Specifically, HEIDENHAIN’s pencil probe-style SPECTO length gauge series now ... new 1Vpp, 12mm stroke length variants of the SPECTO ... a variant with a weak spring, 0.4N of gauging ...
Breaking Biology Technology:23andMe Appoints Kate Black as Privacy Officer and Corporate Counsel 2Protiviti Governance Portal Helps Companies Drive Governance, Risk and Compliance Productivity Across Multiple Business Units 2Protiviti Governance Portal Helps Companies Drive Governance, Risk and Compliance Productivity Across Multiple Business Units 3NuGene International, Inc. Selects Capital Market Relations for Strategic Investor Relations 2NuGene International, Inc. Selects Capital Market Relations for Strategic Investor Relations 3Accuracy and Versatile Gauging Go Hand in Hand at HEIDENHAIN 2
... , , , ... keystone of indirect land use study - Searchinger et al. ... John Mathews and Dr. Hao Tan, researchers from Macquarie University in Sydney, ... revealed that the framework used was inappropriate in that it started with ...
... from the Chinese Academy of Sciences and Nano-Science Center, ... nanoscale electric contacts out of organic and inorganic nanowires. ... like Mikado sticks and coupled several contacts together in ... prototype computer electronics on the nanoscale. ...
... Andrea Armani and Ellis Meng, Both from Viterbi School for ... in September , , LOS ANGELES and ... today announced that two faculty members from the USC Viterbi School ... as some of the world,s top innovators under the age of ...
Cached Biology Technology:Analysis of Biofuels Indirect Land Use Effects Finds the Science Lacking: 'Too Diffuse and Subject To Too Many Arbitrary Assumptions To Be Useful for Rule-making.' 2Analysis of Biofuels Indirect Land Use Effects Finds the Science Lacking: 'Too Diffuse and Subject To Too Many Arbitrary Assumptions To Be Useful for Rule-making.' 3New material for nanoscale computer chips 2Two University of Southern California Innovators Recognized by Technology Review's Prestigious TR35 Listing of the World's Top Young Innovators for 2009 2Two University of Southern California Innovators Recognized by Technology Review's Prestigious TR35 Listing of the World's Top Young Innovators for 2009 3Two University of Southern California Innovators Recognized by Technology Review's Prestigious TR35 Listing of the World's Top Young Innovators for 2009 4Two University of Southern California Innovators Recognized by Technology Review's Prestigious TR35 Listing of the World's Top Young Innovators for 2009 5
QPRT Antibody...
Protein Marker Detection Pack contains biotinylate...
Mouse monoclonal [4C4] to Y14 ( Abpromise for all tested applications). entrezGeneID: 9939 SwissProtID: Q9Y5S9...
JMJD2B Antibody...
Biology Products: