Navigation Links
New paper describes how DNA avoids damage from UV light
Date:7/31/2014

BOZEMAN, Mont. In the same week that the U.S. surgeon general issued a 101-page report about the dangers of skin cancer, researchers at Montana State University published a paper breaking new ground on how DNA the genetic code in every cell responds when exposed to ultraviolet (UV) light.

The findings advance fundamental understanding of DNA damage by the UV rays found in sunlight. This damage can lead to skin cancer, aging and some degenerative eye diseases.

"Our paper advances foundational knowledge about how DNA responds to UV radiation. In our experiments, we observe the earliest events immediately after DNA is energized by UV radiation. These events determine whether or not DNA is damaged," said one of the paper's co-authors, Bern Kohler, an MSU professor in the Department of Chemistry and Biochemistry.

DNA is built like a staircase and carries genetic instructions that are unique to each person. It's very hardy and generally able to stand up to ultraviolet rays, but UV rays sometimes cause mutations. UV exposure is a major cause of skin cancer, and while there are nearly 5 million cases of skin cancer each year in the U.S. alone and 9,000 related deaths the numbers would be far worse if DNA were more easily damaged.

"UV is actually very damaging, yet our DNA is damaged less than expected," Kohler said. "In the early evolution of life on Earth when there was no ozone layer, the amount of UV would have been far higher and yet life, and the DNA that is central to life, survived. We've been trying to understand the molecular mechanisms that make DNA resist UV damage."

In a paper published July 28 in the online version of the scientific journal, "Proceedings of the National Academy of Sciences" (PNAS), Kohler and his colleagues from MSU, Utah and Italy describe how DNA has a super-fast way of shrugging off the UV threat.

Too quick for the eye to see, UV light causes an electron to be tr
'/>"/>

Contact: Evelyn Boswell
evelynb@montana.edu
406-994-5135
Montana State University
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. New paper amplifies hypothesis on human languages deep origins
2. Rising star uses paper to tackle food-borne diseases
3. Researchers receive top honors for ecology paper
4. Researchers design trees that make it easier to produce paper
5. Nano-paper filter removes viruses
6. Telecoupling paper honored as 2013s best
7. Analytical and Bioanalytical Chemistry Best Paper Award to Sherrie Elzey and De-Hao Tsai
8. Paper offers insights into network that plays crucial role in cell function and disease
9. Two papers unraveled the mystery of sex determination and benthic adaptation of the flatfish
10. The Protein Society announces the selection of 2 Protein Science Best Paper speakers
11. Paper predicts a future without carnivores would be truly scary
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/19/2015)... Conn. , March 19, 2015  NXT-ID, Inc. (NASDAQ: ... authentication company focused on the growing mobile commerce market, announces ... in a news clip that aired this week on ... ) . In a segment "The Next Great ... wallet ,a new way to pay, and ,a really big ...
(Date:3/17/2015)... 17, 2015 MedNet Solutions , ... clinical study management systems, is pleased to announce ... ARENA,s Outsourcing in Clinical Trials Southeast conference – ... an excellent forum for MedNet to showcase ... software-as-a-service (SaaS) eClinical technology platform. We ...
(Date:3/17/2015)... 2015  MecklerMedia Corporation (OTCQX: MECK) announced its ... robots ever held in New York ... 11-13, 2015 at the Javits Convention Center. ... include: Acorn Product Development; Axis NJ; c-Link Systems; ... Littler; NewBotic Corporation; Neya Systems LLC; Reliabotics; RoboKind; ...
Breaking Biology News(10 mins):NXT-ID's Wocket Smart Wallet Featured on Fox News Segment, "The Next Great Thing" 2NXT-ID's Wocket Smart Wallet Featured on Fox News Segment, "The Next Great Thing" 3Connect With MedNet Solutions At Outsourcing In Clinical Trials Southeast 2MecklerMedia's RoboUniverse New York Announces Sponsors and Exhibitors, May 11-13, 2015 2
... notorious for their thick skin and well-armored bodies. So it comes ... touch is one of the most acute in the animal kingdom. ... of small, pigmented domes that dot their skin all over their ... jaws. A new study, published in the Nov. 8 issue ...
... 7, 2012 Listed below are the selected highlights for ... journal, GENETICS . The November issue is available ... , Vol. 192, November 2012, Copyright 2012. Please ... in these articles. ISSUE HIGHLIGHTS , An ...
... Every week in his clinic at the University of Michigan, ... dying or shrinking due to disease or injury. ... other effects that nerve-destroying conditions cause and wishes he ... regenerate their nerves. Then he heads to his research lab ...
Cached Biology News:Despite their thick skins, alligators and crocodiles are surprisingly touchy 2Despite their thick skins, alligators and crocodiles are surprisingly touchy 3Genetics Society of America's GENETICS journal highlights for November 2012 2Genetics Society of America's GENETICS journal highlights for November 2012 3Genetics Society of America's GENETICS journal highlights for November 2012 4Stem cells + nanofibers = Promising nerve research 2Stem cells + nanofibers = Promising nerve research 3
(Date:3/25/2015)... March 25, 2015 Optimal Research, LLC has ... Excellence (ViE) Award "Best Clinical Site or Trial Network". ... Optimal has been selected as a nominee in this ... a "Highly Recommended" distinction in 2014. The ViE awards ... efforts, accomplishments, and positive contributions of companies and individuals ...
(Date:3/25/2015)... , March 25, 2015  S&P Capital ... Factual Stock Report coverage on Abattis Bioceuticals ... ATTBF; CSE: ATT): is a specialty biotechnology company ... cultivating, licensing and marketing proprietary ingredients, bio-similar compounds, ... in North America . The ...
(Date:3/25/2015)... Md. , March 25, 2015 Accelovance, ... named a finalist for "Best Contract Research Organization" at ... the World Vaccine Congress. This is ... a finalist for the award, winning for "Best Contract ... a "Highly Recommended" distinction in 2013. "We,re ...
(Date:3/25/2015)... UK (PRWEB) March 25, 2015 An ... natural ingredients in all forms of food nutrients, regulatory ... to a substantial rise in demand for natural astaxanthin ... have started to ramp up their capacities to satisfy ... both natural and synthetic source astaxanthin (used in nutraceuticals, ...
Breaking Biology Technology:Optimal Research Nominated 2015 Vaccine Industry Excellence (ViE) Award 2S&P Capital IQ Initiates Coverage on Abattis Bioceuticals Corp. in S&P Capital IQ Factual Stock Reports 2S&P Capital IQ Initiates Coverage on Abattis Bioceuticals Corp. in S&P Capital IQ Factual Stock Reports 3S&P Capital IQ Initiates Coverage on Abattis Bioceuticals Corp. in S&P Capital IQ Factual Stock Reports 4S&P Capital IQ Initiates Coverage on Abattis Bioceuticals Corp. in S&P Capital IQ Factual Stock Reports 5Accelovance Nominated for 2015 Vaccine Industry Excellence (ViE) Awards 2Global Astaxanthin Market to Reach Value of USD 1.1 billion by 2020, Expects Industry Experts in New Report Available at MarketPublishers.com 2
... Inc. , a software developer for off-road mapping applications, closed ... deal with Kegonsa Capital Partners that values the ... in funds that will enable it to furhter develop its ... vehicles - maps that are designed to interface with global ...
... looking for health information technology to have a moderating ... while longer, according to the head of an influential ... CEO of the Healthcare Information and Management Systems ... improving interoperability between facilities remain high IT priorities, but ...
... a trade owner have to purchase all relevant domain names ... does not register all the variations, are they free for ... defunct businesses? , ,These are questions posed by a ... on its own facts, the following principles can be used ...
Cached Biology Technology:Wausau start up secures $560K for GPS maps 2Wausau start up secures $560K for GPS maps 3CEO of healthcare group still hopeful IT will save employers money 2CEO of healthcare group still hopeful IT will save employers money 3Is your business domain at risk? 2Is your business domain at risk? 3Is your business domain at risk? 4
Anti-CoralHue Dronpa Green Monoclonal Antibody Research Focus: cell surface antigens Storage: -20C Shipping Temperature: +4C...
Phospho-FKHR (Thr24)/FKHRL1 (Thr32) Antibody...
Prostaglandin-E2 receptor EP2/EP3 Market Segment: GPCRs...
... - Red, 20X Immunogen ... at 20X concentration for use in ... Quality Assurance ... fluorescence polarization assays. ...
Biology Products: