Navigation Links
New organic catalyst should enhance drug research and development
Date:5/11/2011

of inventive, creative technology, and our close relationship with the university that is helping us to keep jobs and production here in Oregon and the U.S.

"That's very exciting," Standen said. "And we really believe that organocatalysis is a field that's about ready to blossom, to become an important part of a $350 billion drug development industry."

Catalysts are chemical compounds that help facilitate other chemical reactions without themselves being consumed in industrial production, they can be used over and over. Most medicinal drugs are based on what are called chiral molecules, which are like two mirror images that fit together like a lock and key. A catalyst is often used to induce molecules to become chiral and give them the ability to treat disease.

Existing approaches to create these chiral compounds, however, often use toxic metals, which can also be expensive and create waste disposal issues. By contrast, an "organocatalyst" can not only work better and cost less, but eliminate the environmental concerns.

This particular catalyst was invented by OSU scientists because nothing else that existed was working for one of the compounds they were trying to develop. It was only after creating it that they realized it had a huge range of possible applications in the broader field of drug development.

The Hua Cat catalyst is derived from innocuous compounds such as amino acids, soaps and cleaning solvents. It has a solubility that's 10 times higher than related compounds now being used for drug development. That solubility and its unique chemical reactivity should make it a very important product to facilitate new drug discoveries, OSU researchers say.

Continuing research is already developing variants on the Hua Cat catalyst that should have other useful applications, they said.


'/>"/>

Contact: Rich Carter
rich.carter@oregonstate.edu
541-737-9486
Oregon State University
Source:Eurekalert

Page: 1 2

Related biology news :

1. JHU chemists devise self-assembling organic wires
2. Global warming is changing organic matter in soil
3. Organic plant waste proves effective weed control for citrus trees
4. Organic soils continue to acidify despite reduction in acidic deposition
5. British journal publishes inorganic chemistry research of NJIT professor
6. Controlling cucumber beetles organically
7. Engineers develop method to disperse chemically modified graphene in organic solvents
8. Can organic cropping systems be as profitable as conventional systems?
9. Can organic cropping systems be as profitable as conventional systems?
10. NTU professor discovers method to efficiently produce less toxic drugs using organic molecules
11. Organic food not nutritionally better than conventionally-produced food
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/9/2015)... , July 9, 2015  Synaptics Inc. ... of human interface solutions, today announced a ... first fully hardware encapsulated fingerprint sensor and ... technology is literally off the grid, isolating ... matching within the fingerprint sensor to provide ...
(Date:7/8/2015)... YORK , July 8, 2015  BD (Becton, ... BD & Guidepoint Mentor, a new program ... Guidepoint,s expert network services. BD is ... to improve healthcare delivery and outcomes and, with the ... entrepreneur will be able to directly engage with industry ...
(Date:7/8/2015)... -- The consumer products industry for innovative tech ... such as wearables, smart wallets & other smart technology are ... continues to rapidly grow.  Biometrics & Wearable Device Companies in ... Inc. (NASDAQ: GOOG ), Apple Inc. (NASDAQ: AAPL ... GPRO ) and Baidu Inc. (NASDAQ: BIDU ) ...
Breaking Biology News(10 mins):Synaptics Announces World's First Match-in-Sensor Fingerprint Authentication Technology 2Synaptics Announces World's First Match-in-Sensor Fingerprint Authentication Technology 3BD and Guidepoint Team to Connect Healthcare Start-up Companies With Business and Scientific Experts 2BD and Guidepoint Team to Connect Healthcare Start-up Companies With Business and Scientific Experts 3Consumers Flock to This Summer's Must Have Tech Gadgets as Latest Digital Wallets, Smart Technology & Wearable Products Continue to Grow in Popularity & Functionality 2Consumers Flock to This Summer's Must Have Tech Gadgets as Latest Digital Wallets, Smart Technology & Wearable Products Continue to Grow in Popularity & Functionality 3Consumers Flock to This Summer's Must Have Tech Gadgets as Latest Digital Wallets, Smart Technology & Wearable Products Continue to Grow in Popularity & Functionality 4Consumers Flock to This Summer's Must Have Tech Gadgets as Latest Digital Wallets, Smart Technology & Wearable Products Continue to Grow in Popularity & Functionality 5Consumers Flock to This Summer's Must Have Tech Gadgets as Latest Digital Wallets, Smart Technology & Wearable Products Continue to Grow in Popularity & Functionality 6
... the most common gene mutation found in acute myeloid ... it can cooperate with a well-defined group of other ... that three critical steps are required to transform normal ... cellular process. By charting the route towards cancer, the ...
... and the National Institute for Basic Biology, Japan, have ... underlying genetic and environmental sex determination. The scientists report ... identification of a gene responsible for the production of ... Daphnia . Ways in which an individual ...
... and colleagues at the Colorado School of Mines could ... work describes how the size of light-absorbing particles--quantum dots--affects ... generate electricity. The results are published in the ... The advance provides evidence to support a controversial ...
Cached Biology News:The gene processes that drive acute myeloid leukaemia 2The gene processes that drive acute myeloid leukaemia 3An ancestral link between genetic and environmental sex determination 2Size matters: Smaller particles could make solar panels more efficient 2
(Date:7/29/2015)... , July 30, 2015 According ... Market - Growth, Trends & Forecasts (2015-2020), , published by ... US$ 30.25 billion by the end of 2020, with ... accounting for more than 40% of the global market size. ... at a CAGR of 13.7% during the period of (2015-2020). ...
(Date:7/29/2015)... / Japan (Q2 2015: +14% CER / 20% ... high-single-digit growth in China , as well as solid contributions ... Europe / Middle East / ... showed gains in Germany , Turkey ... CER / 49% of sales) grew 11%, excluding U.S. HPV sales, on demand ...
(Date:7/29/2015)... 29, 2015  HealthSouth Corporation (NYSE: ... of post-acute healthcare services, offering both facility-based and ... operations for the second quarter ended June 30, 2015. ... by strong volume growth in both segments and ... Jay Grinney, President and Chief Executive Officer of ...
(Date:7/29/2015)... (PRWEB) , ... July 29, 2015 , ... ... manufacturer and supplier, announces the launch of their 2nd generation cell therapy POD® ... current miniPOD CT, but it also represents a new POD® design. , ...
Breaking Biology Technology:Asia Pacific to Dominate the Global Stem Cell Market - Vericel Corporation, Ocata Therpeutics, Athersys Inc., Cryo-Cell International, Geron Corporation, StemCells, Inc. Among the Major Players 2Asia Pacific to Dominate the Global Stem Cell Market - Vericel Corporation, Ocata Therpeutics, Athersys Inc., Cryo-Cell International, Geron Corporation, StemCells, Inc. Among the Major Players 3QIAGEN Reports Results for Second Quarter and First Half of 2015 2QIAGEN Reports Results for Second Quarter and First Half of 2015 3QIAGEN Reports Results for Second Quarter and First Half of 2015 4QIAGEN Reports Results for Second Quarter and First Half of 2015 5QIAGEN Reports Results for Second Quarter and First Half of 2015 6QIAGEN Reports Results for Second Quarter and First Half of 2015 7QIAGEN Reports Results for Second Quarter and First Half of 2015 8QIAGEN Reports Results for Second Quarter and First Half of 2015 9QIAGEN Reports Results for Second Quarter and First Half of 2015 10HealthSouth Reports Results for Second Quarter 2015 2HealthSouth Reports Results for Second Quarter 2015 3HealthSouth Reports Results for Second Quarter 2015 4HealthSouth Reports Results for Second Quarter 2015 5HealthSouth Reports Results for Second Quarter 2015 6HealthSouth Reports Results for Second Quarter 2015 7HealthSouth Reports Results for Second Quarter 2015 8HealthSouth Reports Results for Second Quarter 2015 9HealthSouth Reports Results for Second Quarter 2015 10HealthSouth Reports Results for Second Quarter 2015 11HealthSouth Reports Results for Second Quarter 2015 12HealthSouth Reports Results for Second Quarter 2015 13HealthSouth Reports Results for Second Quarter 2015 14HealthSouth Reports Results for Second Quarter 2015 15HealthSouth Reports Results for Second Quarter 2015 16HealthSouth Reports Results for Second Quarter 2015 17HealthSouth Reports Results for Second Quarter 2015 18HealthSouth Reports Results for Second Quarter 2015 19HealthSouth Reports Results for Second Quarter 2015 20HealthSouth Reports Results for Second Quarter 2015 21HealthSouth Reports Results for Second Quarter 2015 22HealthSouth Reports Results for Second Quarter 2015 23HealthSouth Reports Results for Second Quarter 2015 24HealthSouth Reports Results for Second Quarter 2015 25
... 4 Thermage, Inc.,(Nasdaq: THRM ), a ... announced today that it will present at the ... Palace Hotel in New York City. The,Company,s presentation ... 11:00,a.m. Eastern Time. Stephen J. Fanning, Chairman, President ...
... of Jerusalem has discovered a way to literally catch terrorists ... Joseph Almog of the Hebrew University,s Casali Institute of Applied ... cotton swabs taken from the hands of a suspect, if ... will turn a blood red hue. , Urea nitrate is ...
... of gallons of hazardous waste resulting from the nations ... southeastern Washington state called Hanford. Beneath this desert ... of thousands of tons of chemicals are captured within ... complex subsurface flow paths. These paths create uncertainties ...
Cached Biology Technology:HU scientist finds way to catch terrorists red-handed 2Where does stored nuclear waste go? 2
... KLH-conjugated, synthetic peptide corresponding ... of mouse p19ARF. The ... acids 62-75. Clone 5-C3-1. ... by immunoblot. Stability ...
... siSolutions siRNA Custom Synthesis Service ... duplex RNA to knockdown any ... (19 RNA base pairs with ... 27-mers, or other lengths of ...
Request Info...
Tracker Datamatrix RS-1* reads 96 2D Bar-coded tubes within 20 seconds....
Biology Products: