Navigation Links
New on-off 'switch' triggers and reverses paralysis in animals with a beam of light
Date:11/18/2009

In an advance with overtones of Star Trek phasers and other sci-fi ray guns, scientists in Canada are reporting development of an internal on-off "switch" that paralyzes animals when exposed to a beam of ultraviolet light. The animals stay paralyzed even when the light is turned off. When exposed to ordinary light, the animals become unparalyzed and wake up. Their study appears in the Journal of the American Chemical Society (JACS). It reports the first demonstration of such a light-activated switch in animals.

Neil Branda and colleagues point out that such "photoswitches" -- light-sensitive materials that undergo photoreactions -- have been available for years. Scientists use them in research. Doctors use light-sensitive materials and photoreactions in medicine in photodynamic therapy to treat certain forms of cancer. Those light-sensitive materials, however, do not have the reversibility that exists in photoswitching.

The JACS report describes development and successful testing of a photoswitch composed of the light-sensitive material, dithienylethene. The scientists grew transparent, pinhead-sized worms (C. elegans) and fed them a dithienylethene. When exposed to ultraviolet light, the worms turned blue and became paralyzed. When exposed to visible light, the dithienylethene became colorless again and the worms' paralysis ended. Many of the worms lived through the paralyze-unparalyze cycle. Scientists were not sure how the switch causes paralysis. The study demonstrates that photoswitches may have great potential in turning photodynamic therapy on and off, and for other applications in medicine and research, they indicate.


'/>"/>

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society
Source:Eurekalert  

Page: 1

Related biology news :

1. Novel on-off switch mechanism stops cancer in its tracks
2. Biochemical on-switch could solve protein purification challenge
3. Alcohol tolerance switch found
4. Advanced Analogic Technologies Introduces Lowest-Power Load Switch Available for Biometric Security Devices
5. Master gene that switches on disease-fighting cells identified by scientists
6. NC State receives NSF grant to discover plant switchboards
7. Switching on the power of stem cells
8. Estrogen-dependent switch tempers killing activity of immune cells
9. Fujitsu Expands Support for Ethernet Networks With New Additions to XG Switch Product Line
10. Just in time for spring: Scientists find the cellular on and off switch for allergies and asthma
11. Researchers discover that gene switches on during development of epilepsy
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New on-off 'switch' triggers and reverses paralysis in animals with a beam of light
(Date:7/29/2014)... Schools of Dentistry (UM SOD) and Medicine (UM ... a five-year $10.7 million grant award from the ... of the National Institutes of Health to study ... (STDs). The grant, which renews a previous $12 ... direction for the research by studying chlamydial and ...
(Date:7/29/2014)... ground breaking new book that brings together two of ... raise the profile of insect fossils through stunning photographs ... Penney and James E Jepson, details the incredible preservation ... setting the scene for what these remarkable fossils can ... even the future of our planet. Like the mosquito ...
(Date:7/28/2014)... new discovery of two additional coral communities showing signs of ... footprint of the 2010 spill in the Gulf of Mexico. ... Fisher, professor of biology at Penn State University. A paper ... corals in the Gulf of Mexico will be published during ... Edition of the journal Proceedings of the National Academy ...
Breaking Biology News(10 mins):University of Maryland Schools of Dentistry and Medicine receive NIH grant 2University of Maryland Schools of Dentistry and Medicine receive NIH grant 3University of Maryland Schools of Dentistry and Medicine receive NIH grant 4Unique images bring fossil insects back to life 2Impact of Deepwater Horizon oil spill on coral is deeper and broader than predicted 2
... Bluefin Are Skinny DURHAM, N.H. The quality ... Maine has declined significantly since the early 1990s, researchers ... analyzing detailed logbooks from a commercial tuna grader at ... in Fishery Bulletin, indicate potential changes in food sources, ...
... syndrome is a common problem in children 8 years of ... Kingdom, according to a new report from an international team ... to 17 are affected, and a significant proportion of those ... moods. The report appears in the August issue of the ...
... University of Minnesota Medical School and Brain Sciences Center ... noninvasive and painless way to diagnose complex brain diseases. ... of light.The research offers promise for a less-stressful, painless, ... a way to measure the effectiveness of different treatments ...
Cached Biology News:Condition of bluefin tuna in gulf of maine is declining 2Condition of bluefin tuna in gulf of maine is declining 3Restless legs syndrome affects nearly 2 percent of US/UK children 2Restless legs syndrome affects nearly 2 percent of US/UK children 3U of MN researchers discover noninvasive diagnostic tool for brain diseases 2
(Date:7/29/2014)... “PharmaSphere: Emerging Biotech Investment Report ... Funding” report provides in-depth analysis of the current ... venture capital segments of the financial industry, bearing ... significant impact on the future of emerging biotechnology ... report identifies regions of the world that are ...
(Date:7/29/2014)... significant technological challenges in their quest to improve ... the James Webb Space Telescope. , The team, ... at NASA,s Goddard Space Flight Center in Greenbelt, ... that is, those activated by applying an ... current technology,s magnetically activated arrays. This advance makes ...
(Date:7/29/2014)... The advanced optical methods and applications ... driving a revolution in the neurosciences were the inspiration ... by SPIE, the international society for optics and ... launch of the BRAIN Initiative in the United States, ... a vision for and provide examples of the impact ...
(Date:7/29/2014)... , July 29, 2014   Sequenom, Inc. ... that provides innovative genetic analysis solutions, and Mayo ... laboratory services in the United States ... testing patents and applications. "We have great ... patient care, and we welcome the opportunity to partner ...
Breaking Biology Technology:Strategic Trends of Biotech Investment Industry (Private Equity and Venture Capital Funding) in New Report Available at MarketOptimizer.org 2Strategic Trends of Biotech Investment Industry (Private Equity and Venture Capital Funding) in New Report Available at MarketOptimizer.org 3Strategic Trends of Biotech Investment Industry (Private Equity and Venture Capital Funding) in New Report Available at MarketOptimizer.org 4Revolutionary microshutter technology hurdles significant challenges 2Revolutionary microshutter technology hurdles significant challenges 3Revolutionary microshutter technology hurdles significant challenges 4SPIE Launches 'Neurophotonics' Journal with Special Section on BRAIN Initiative 2SPIE Launches 'Neurophotonics' Journal with Special Section on BRAIN Initiative 3SPIE Launches 'Neurophotonics' Journal with Special Section on BRAIN Initiative 4Sequenom Enters Into License Agreement With Mayo Medical Laboratories 2Sequenom Enters Into License Agreement With Mayo Medical Laboratories 3Sequenom Enters Into License Agreement With Mayo Medical Laboratories 4
... by SkyPilot Networks at Hamburger University in Oak Brook, Ill., ... rally municipal attendees. He said we need to focus on ... , ,Quinn had some encouraging remarks about keeping the playing ... blockading. He has made this a priority in his job ...
... - Seven emerging companies in the Chippewa Valley are vying ... and, eventually, a needed dose of public awareness as part ... by the Eau Claire Area Economic Development Corporation . ... year, seven applicants have been invited to submit full business ...
... every any doubt, let me assure you that DEMOletter blog readers ... up this space to any reader who had a perspective, opinion, ... Jim Forbes responded. And it seems even Jim prefers the ... again being edited by me. , ,Most of you, I suppose, ...
Cached Biology Technology:Municipal broadband in Illinois: Where are the standards? 2Municipal broadband in Illinois: Where are the standards? 3Municipal broadband in Illinois: Where are the standards? 4Eau Claire business contest down to 7 applicants 2The DEMO Summer Reading List 2The DEMO Summer Reading List 3
... system, 100-240 V, uses xMAP technology for ... proteins and peptides in one microplate well. ... to 100 color-coded bead sets, each of ... reactant (enzyme substrates, receptors, antigens, or antibodies) ...
Cell Culture Flask, 75 cm, treated polystyrene...
...
... These 50ml PYREX Delong style shaker ... to provide greater agitation of solutions to ... with rotary or reciprocating shakers. The long ... two-position polypropylene closures. Their uniform wall thickness ...
Biology Products: