Navigation Links
New on-off 'switch' triggers and reverses paralysis in animals with a beam of light

In an advance with overtones of Star Trek phasers and other sci-fi ray guns, scientists in Canada are reporting development of an internal on-off "switch" that paralyzes animals when exposed to a beam of ultraviolet light. The animals stay paralyzed even when the light is turned off. When exposed to ordinary light, the animals become unparalyzed and wake up. Their study appears in the Journal of the American Chemical Society (JACS). It reports the first demonstration of such a light-activated switch in animals.

Neil Branda and colleagues point out that such "photoswitches" -- light-sensitive materials that undergo photoreactions -- have been available for years. Scientists use them in research. Doctors use light-sensitive materials and photoreactions in medicine in photodynamic therapy to treat certain forms of cancer. Those light-sensitive materials, however, do not have the reversibility that exists in photoswitching.

The JACS report describes development and successful testing of a photoswitch composed of the light-sensitive material, dithienylethene. The scientists grew transparent, pinhead-sized worms (C. elegans) and fed them a dithienylethene. When exposed to ultraviolet light, the worms turned blue and became paralyzed. When exposed to visible light, the dithienylethene became colorless again and the worms' paralysis ended. Many of the worms lived through the paralyze-unparalyze cycle. Scientists were not sure how the switch causes paralysis. The study demonstrates that photoswitches may have great potential in turning photodynamic therapy on and off, and for other applications in medicine and research, they indicate.


Contact: Michael Bernstein
American Chemical Society

Page: 1

Related biology news :

1. Novel on-off switch mechanism stops cancer in its tracks
2. Biochemical on-switch could solve protein purification challenge
3. Alcohol tolerance switch found
4. Advanced Analogic Technologies Introduces Lowest-Power Load Switch Available for Biometric Security Devices
5. Master gene that switches on disease-fighting cells identified by scientists
6. NC State receives NSF grant to discover plant switchboards
7. Switching on the power of stem cells
8. Estrogen-dependent switch tempers killing activity of immune cells
9. Fujitsu Expands Support for Ethernet Networks With New Additions to XG Switch Product Line
10. Just in time for spring: Scientists find the cellular on and off switch for allergies and asthma
11. Researchers discover that gene switches on during development of epilepsy
Post Your Comments:
Related Image:
New on-off 'switch' triggers and reverses paralysis in animals with a beam of light
(Date:5/20/2016)... MINNEAPOLIS , May 20, 2016  VoiceIt ... technology partnership with VoicePass. By working ... user experience.  Because VoiceIt and VoicePass take slightly ... two engines increases both security and usability. ... expressed excitement about this new partnership. ...
(Date:5/12/2016)... , May 12, 2016 , ... published the overview results from the Q1 wave of ... recent wave was consumers, receptivity to a program where ... with a health insurance company. "We were ... share," says Michael LaColla , CEO of Troubadour ...
(Date:5/3/2016)... Lithuania , May 3, 2016  Neurotechnology, ... released the MegaMatcher Automated Biometric Identification System ... of large-scale multi-biometric projects. MegaMatcher ABIS can process ... accuracy using any combination of fingerprint, face or ... MegaMatcher SDK and MegaMatcher Accelerator ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... MA (PRWEB) , ... June 23, 2016 , ... ... Peel Plate® YM (Yeast and Mold) microbial test has received AOAC Research Institute ... platform of microbial tests introduced last year,” stated Bob Salter, Vice President of ...
(Date:6/23/2016)... ... June 23, 2016 , ... STACS DNA Inc., the ... at the Arkansas State Crime Laboratory, has joined STACS DNA as a Field Application ... team,” said Jocelyn Tremblay, President and COO of STACS DNA. β€œIn further expanding our ...
(Date:6/23/2016)... , June 23, 2016 On ... session at 4,833.32, down 0.22%; the Dow Jones Industrial Average ... 500 closed at 2,085.45, down 0.17%. has initiated coverage ... INFI ), Nektar Therapeutics (NASDAQ: NKTR ), Aralez ... Inc. (NASDAQ: BIND ). Learn more about these ...
(Date:6/23/2016)... 23, 2016 adds ... to its pharmaceuticals section with historic and forecast ... much more. Complete report on the ... profiling 15 companies and supported with 261 tables ... . The Global Cell Culture ...
Breaking Biology Technology: