Navigation Links
New nucleotide could revolutionize epigenetics
Date:4/16/2009

ting a dynamic system for regulating gene expression through 5-hydroxymethylcytosine. Kriaucionis and Heintz did not know of the other group's work, led by Anjana Rao, until earlier this month. "You look at our result, and the beautiful studies of the enzymology by Dr. Rao's group, and realize that you are at the tip of an iceberg of interesting biology and experimentation," says Heintz, a neuroscientist whose research has not focused on epigenetics in the past. "This finding of an enzyme that can convert 5-methylcytosine to 5-hydroxymethylcytosine establishes this new epigenetic mark as a central player in the field."

Kriaucionis is now mapping the sites where 5-hydroxymethylcytosine is present in the genome, and the researchers plan to genetically modify mice to under- or overexpress the newfound nucleotide in specific cell types in order to study its effects. "This is a major discovery in the field, and it is certain to be tied to neural function in a way that we can decipher," Heintz says.


'/>"/>

Contact: Brett Norman
bnorman@rockefeller.edu
212-327-7613
Rockefeller University
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. Long-lasting nerve block could change pain management
2. Biofuels could hasten climate change
3. Public trust doctrine could aid management of US oceans
4. New therapeutic strategy could target toxic protein in most patients with Huntingtons disease
5. Research could lead to new non-antibiotic drugs to counter hospital infections
6. Locking parasites in host cell could be new way to fight malaria
7. Gene discovery could lead to male contraceptive
8. MIT: Novel needle could cut medical complications
9. New wheat disease could spread faster than expected
10. Uvalde Center water research could have national, international applications
11. Texas Board of Education vote on the way evolution is taught could set national trend
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/25/2014)... the age girls reach puberty is influenced by ,imprinted genes,a ... contributes the gene. This is the first evidence that ... and details of this study were published today in the ... known as menarche, is a marker for the timing of ... of menses varies between girls, is an inherited trait, and ...
(Date:7/25/2014)... CORAL SPRINGS, Florida , July 25, 2014 /PRNewswire/ ... influential as more consumers are turning to digital technology ... NXT-ID, Inc. (OTCBB: NXTD), Google Inc. (NASDAQ: ... Visa Inc. (NYSE: V ), Apple Inc. ... FTNT) NXT-ID, Inc., (OTCQB: NXTD) a biometric ...
(Date:7/24/2014)... July 24, 2014 /PRNewswire-iReach/ -- The Geneva Healthcare Suite, ... devices, has cut emergency room wait times by an ... (UCSD) Medical Center, according to a recent study published ... Departments are using the suite to access data from ... defibrillators. "Using Geneva,s technology platform we have ...
Breaking Biology News(10 mins):Could age of first period influence development of diseases in older women? 2Consumer Needs for Identity Theft Security Grows with Popularity of Latest Smart Technology Products - Biometrically Secure Digital Wallet to Replace Credit Card Dependency 2Consumer Needs for Identity Theft Security Grows with Popularity of Latest Smart Technology Products - Biometrically Secure Digital Wallet to Replace Credit Card Dependency 3Consumer Needs for Identity Theft Security Grows with Popularity of Latest Smart Technology Products - Biometrically Secure Digital Wallet to Replace Credit Card Dependency 4Consumer Needs for Identity Theft Security Grows with Popularity of Latest Smart Technology Products - Biometrically Secure Digital Wallet to Replace Credit Card Dependency 5Consumer Needs for Identity Theft Security Grows with Popularity of Latest Smart Technology Products - Biometrically Secure Digital Wallet to Replace Credit Card Dependency 6UC San Diego Medical Center Cuts Average ER Wait Time by 92 Minutes using the Geneva Healthcare Suite 2UC San Diego Medical Center Cuts Average ER Wait Time by 92 Minutes using the Geneva Healthcare Suite 3
... its introduction fifty or so years ago, thermography has been ... in horses. The method is fast and safe and ... surface emits infrared radiation that can be detected by an ... The camera produces a coloured image that shows the ...
... received a $12 million grant from the National Institutes ... research on aphasia, a devastating language disorder that essentially ... U.S. alone, more than one million people suffer from ... will direct the new Center for the Neurobiology of ...
... dioxide in the Earth,s atmosphere created by the widespread burning ... climate change, and researchers the world over are looking for ... footprint. Now, researchers at the University of Georgia ... in the atmosphere into useful industrial products. Their discovery may ...
Cached Biology News:Blowing in the wind: How accurate is thermography of horses' legs? 2$12 million for a center for research on aphasia 2$12 million for a center for research on aphasia 3UGA discovery may allow scientists to make fuel from CO2 in the atmosphere 2
(Date:7/24/2014)... July 24, 2014 Gain recognition ... Supply Chain of the biotech industry. Nominations are ... Awards, brought to you by the Bio ... of supply chain management professionals for the past ... stakeholders of the Biotech industry – Manufacturers, Service ...
(Date:7/24/2014)... equipment, trained personnel, and detection dogs to safeguard ... A revolutionary new electronic chip with nano-sized chemical ... easier. , The groundbreaking nanotechnology-inspired sensor, devised by ... School of Chemistry and Center for Nanoscience and ... picks up the scent of explosives molecules better ...
(Date:7/24/2014)... prefer to settle into equilibriuma state of unchanging ... realm of non-equilibrium conditions where new possibilities lie. ... phases, such as temperature fluctuations, freezing and melting, ... their body temperature, airplanes to fly, and the ... But even though these conditions exist naturally and ...
(Date:7/24/2014)... , July 24, 2014 SRI International has ... the National Institute of Allergy and Infectious Diseases (NIAID), ... preclinical development of potential therapies for HIV infection and ... treat HIV and AIDS and the complications and opportunistic ... for preventing sexual transmission of HIV. ...
Breaking Biology Technology:Call for Submission: BSMA’s Supply Chain Management Innovation Awards 2Call for Submission: BSMA’s Supply Chain Management Innovation Awards 3Nano-sized chip 'sniffs out' explosives far better than trained dogs 2New approach to form non-equilibrium structures 2National Institute of Allergy and Infectious Diseases Awards SRI International Contract to Study New Therapies for HIV and AIDS 2National Institute of Allergy and Infectious Diseases Awards SRI International Contract to Study New Therapies for HIV and AIDS 3
... EMERYVILLE, Calif., Aug. 3 NovaBay Pharmaceuticals, Inc. ... J. Wu has joined the company as senior vice ... than 30 years of highly successful experience in the ... business development, licensing, international marketing, project management, clinical development, ...
... , BOTHELL, WA and VANCOUVER, Aug. 3 /PRNewswire-FirstCall/ - OncoGenex ... Company will announce second quarter financial results on Thursday, August ... webcast at 4:30 p.m. EDT that afternoon to discuss quarterly ... Relations page of the OncoGenex Web site at www.oncogenex.com ...
... COUNTY, Calif., Aug. 2 Beckman Coulter, Inc. (NYSE: ... products that simplify, automate and innovate complex biomedical testing, announced ... business. This acquisition, first announced in February, extends Beckman ... , (Logo: http://www.newscom.com/cgi-bin/prnh/20031202/BECLOGO ...
Cached Biology Technology:NovaBay(R) Pharmaceuticals Names Roy J. Wu as Senior Vice President for Business Development 2NovaBay(R) Pharmaceuticals Names Roy J. Wu as Senior Vice President for Business Development 3Beckman Coulter Completes Acquisition of Olympus' Lab-Based Diagnostics Business 2