Navigation Links
New nucleotide could revolutionize epigenetics
Date:4/16/2009

ting a dynamic system for regulating gene expression through 5-hydroxymethylcytosine. Kriaucionis and Heintz did not know of the other group's work, led by Anjana Rao, until earlier this month. "You look at our result, and the beautiful studies of the enzymology by Dr. Rao's group, and realize that you are at the tip of an iceberg of interesting biology and experimentation," says Heintz, a neuroscientist whose research has not focused on epigenetics in the past. "This finding of an enzyme that can convert 5-methylcytosine to 5-hydroxymethylcytosine establishes this new epigenetic mark as a central player in the field."

Kriaucionis is now mapping the sites where 5-hydroxymethylcytosine is present in the genome, and the researchers plan to genetically modify mice to under- or overexpress the newfound nucleotide in specific cell types in order to study its effects. "This is a major discovery in the field, and it is certain to be tied to neural function in a way that we can decipher," Heintz says.


'/>"/>

Contact: Brett Norman
bnorman@rockefeller.edu
212-327-7613
Rockefeller University
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. Long-lasting nerve block could change pain management
2. Biofuels could hasten climate change
3. Public trust doctrine could aid management of US oceans
4. New therapeutic strategy could target toxic protein in most patients with Huntingtons disease
5. Research could lead to new non-antibiotic drugs to counter hospital infections
6. Locking parasites in host cell could be new way to fight malaria
7. Gene discovery could lead to male contraceptive
8. MIT: Novel needle could cut medical complications
9. New wheat disease could spread faster than expected
10. Uvalde Center water research could have national, international applications
11. Texas Board of Education vote on the way evolution is taught could set national trend
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/16/2014)... Cancer constantly wages war on the human body. ... a stalemate. In pancreatic cancer, this stalemate—known as ... becoming aggressively malignant, a phenomena that is poorly ... in the laboratory of Salvatore Torquato, a Professor ... the conditions surrounding tumor dormancy and the switch ...
(Date:10/16/2014)... managers have a new synthesis of recent research findings ... forests in the two states. , The Ecology ... and Washington: A Synthesis of the Relevant Biophysical Science ... report published by the U.S. Forest Service,s Pacific Northwest ... from managers for a synthesis of the large body ...
(Date:10/16/2014)... be cultivated efficiently, they are anything but sustainable: ... monoculture cultivation is becoming increasingly evident. Despite their ... and are regarded as the sole possibility of ... wrongfully, finds Bernhard Schmid, an ecology professor at ... form of agriculture and forestry. After all, a ...
Breaking Biology News(10 mins):Modeling tumor dormancy 2New report synthesizes best available science on management of moist mixed-conifer forests 2Plant communities produce greater yield than monocultures 2Plant communities produce greater yield than monocultures 3
... good Nature is full of mimicscreatures that have ... However, some mimics imitate their models more convincingly than others, ... be a bad mimic. The research looked at three species ... accuracy, aggressive and bad-tasting ants. All of the mimics were ...
... in Sweden have discovered that a gene linked to ... the antenna-like projections that cells use to communicate. ... number of genes, the functions of which are, however, ... Helsinki University now shows that one of these genes, ...
... are new genetic clues on risk factors and biological ... palsy (PSP), according to a new study from an ... School of Medicine at the University of Pennsylvania. In ... genes associated with risk for PSP were identified and ...
Cached Biology News:News tips from the July issue of the American Naturalist 2News tips from the July issue of the American Naturalist 3Unexpected function of dyslexia gene 2New genes for risk and progression of rare brain disease identified 2New genes for risk and progression of rare brain disease identified 3
(Date:10/19/2014)... (PRWEB) October 20, 2014 ... Industry Meeting (ABIM). ABIM will take ... More information about ABIM 2014 is now ... , Delegates representing companies and organizations from ... and obtain information on the latest products ...
(Date:10/19/2014)... The Asia-Pacific Bromine Market report defines and segments ... forecast of revenue. , Browse through the TOC ... get an idea of the in-depth analysis provided. ... in the Asia-Pacific bromine market, and is supported ... http://www.micromarketmonitor.com/market/asia-pacific-bromine-6741503144.html , Bromine is a volatile and ...
(Date:10/19/2014)... The Asia-Pacific Speech Analytics market report ... with analysis and forecast of revenue. This market is ... $208 million by 2019, at a Compound Annual Growth ... Browse through the TOC of the Asia-Pacific Speech Analytics ... analysis provided. It also provides a glimpse of the ...
(Date:10/19/2014)... The Asian Orthopedic braces and support systems report defines and ... of revenue. The Orthopedic braces and support systems market in ... 2018, at a developing CAGR of 4.4% from 2013 to ... braces and support systems market, to get an idea of ... the segmentation of orthopedic braces and support systems market in ...
Breaking Biology Technology:The Asia-Pacific Bromine Market is estimated to grow to $4,080.1 million by 2018 - New Report by MicroMarket Monitor 2The Asia-Pacific Bromine Market is estimated to grow to $4,080.1 million by 2018 - New Report by MicroMarket Monitor 3The Asia-Pacific Speech Analytics market is estimated to reach $208 million by 2019 - New Report by MicroMarket Monitor 2The Asia-Pacific Speech Analytics market is estimated to reach $208 million by 2019 - New Report by MicroMarket Monitor 3The Asia-Pacific Speech Analytics market is estimated to reach $208 million by 2019 - New Report by MicroMarket Monitor 4The Asian Orthopedic braces and support systems market is estimated to grow to around $416.5 million by 2018 - New Report by MicroMarket Monitor 2The Asian Orthopedic braces and support systems market is estimated to grow to around $416.5 million by 2018 - New Report by MicroMarket Monitor 3The Asian Orthopedic braces and support systems market is estimated to grow to around $416.5 million by 2018 - New Report by MicroMarket Monitor 4
... The 10th American Telugu Association (ATA) Conference & Youth Convention, an upcoming ... Newark, New Jersey, is all set to receive more than 10,000 people ... ... -- One of the key highlights of the convention is the Business ...
... COLUMBIA, Md., June 26 A study ... indicates that higher DHA levels are,associated with ... children. The study, "Assessing the Effect of ... Children: A Randomized,Placebo- Controlled, Double-Blind Study," evaluated ...
... ValGenesis, Inc., a leading,provider of Enterprise ... of ValGenesis 2.0, the latest version of ... and automation product., Life science companies ... the entire validation life cycle and move ...
Cached Biology Technology:American Telugu Association's Convention Attracts Over 10,000 People in the U.S. 2American Telugu Association's Convention Attracts Over 10,000 People in the U.S. 3American Telugu Association's Convention Attracts Over 10,000 People in the U.S. 4Results of Study in Pre-School Children Published in Clinical Pediatrics Adds to Support for Importance of Dietary DHA Intake 2Results of Study in Pre-School Children Published in Clinical Pediatrics Adds to Support for Importance of Dietary DHA Intake 3Results of Study in Pre-School Children Published in Clinical Pediatrics Adds to Support for Importance of Dietary DHA Intake 4ValGenesis, Inc. Announces Worldwide Release of Validation Life Cycle Management System - ValGenesis 2.0 2ValGenesis, Inc. Announces Worldwide Release of Validation Life Cycle Management System - ValGenesis 2.0 3
Immunogen: MBP-fusion protein of the C-terminal region of the a2 subunit (amino acids K581-D670) Storage: -20 C, Avoid Freeze/Thaw Cycles...
... This antibody recognizes murine IRF7 ... with other related IRF proteins. ... murine IRF7 protein was confirmed ... the 293T cells transfected with ...
... Clone/PAD: PS603. Immunogen: Synthetic ... surrounding the phosphorylated Ser603 residue ... Specificity: Specific for synapsin I ... 3). Reactivity: Rat (positive ...
MMP-20 Immunogen: Activated recombinant human MMP-2 Storage: -20 C, Avoid Freeze/Thaw Cycles...
Biology Products: