Navigation Links
New non-surgical autopsy technique set to revolutionize post-mortem practice

A new non-surgical post-mortem technique that has the potential to revolutionise the way autopsies are conducted around the world has been pioneered by forensic pathologists and radiologists at the University of Leicester in collaboration with the University Hospitals of Leicester NHS Trust.

The technique developed by a team in the East Midlands Forensic Pathology Unit, at the University of Leicester, has been published today (1 March) in International Journal of Legal Medicine. This paper presents the development of the methodology and protocol for this technique from independent research commissioned by the National Institute for Health Research (NIHR).

The study has taken another step towards a minimally invasive autopsy for natural and unnatural deaths, for either single cases or mass fatalities. It could also potentially allay qualms from certain faith groups that object to autopsies.

Professor Guy Rutty, Chief Forensic Pathologist to the East Midlands Forensic Pathology Unit, which is part of the Department of Cancer Studies and Molecular Medicine, University of Leicester, said the pilot study had demonstrated the potential of the technique to change the future of post-mortem procedures.

He said: "Autopsies are not popular with the general public and are viewed with great distaste. There are a number of faith groups who voice objections to the autopsy. The development of a minimally invasive autopsy technique would reduce the overall number of invasive autopsies performed in the UK but would still provide a service to the Coroner and determine the cause of a person's death. Currently, without the use of angiography, cardiac related death cannot be reliably diagnosed using a post mortem CT (Computed Tomography) scan so we needed to develop a system that could do this."

"In collaboration with the radiology team, lead by Professor Bruno Morgan, we have successfully developed a quick and simple technique of 'minimally invasive targeted coronary angiography' where we inject contrast into the body of a deceased person through a small incision in the neck and then perform a full body CT scan. Using this method we are able to determine the cause of death in up to 80% of cases (in the series analysed to date).

"Basically, the technique is used to highlight and examine the vessels of the heart in people who have died. The technique is inexpensive, easy to use and applicable to natural and unnatural death, both single and mass fatalities."

Professor Rutty explained the technique was novel because it uses catheterisation, contrast and imaging techniques that have not been reported previously. "Developing a new catheterisation system and using two different types of contrast to highlight the coronary vessels (air and standard coronary radio-opaque contrast media) sets us apart from other research groups," he said.

Professor Rutty added: "We were the first Unit in the world to our knowledge to propose targeted angiography as the way forward, and are now the first to describe the development, methodology and protocols involved for cadaver cardiac CT angiography. Other groups have done whole body angiography which is time consuming and expensive and is unlikely to be implemented in the UK for everyday autopsies.

"We are incredibly excited about the potential of this new research. This technique could see the beginning of a permanent change in autopsy practice in the UK, with fewer autopsies being performed. This technique could be used in other centres across the world."

The research paper presents the results from an initial pilot of 24 cases. The University team will now complete a further 200 cases this year to further evaluate the technique and build a bigger evidence base.


Contact: University of Leicester Press Office
University of Leicester

Related biology news :

1. NJIT professor finds engineering technique to identify disease-causing genes
2. New technique enables assessment of drought performance
3. New technique eliminates toxic drugs in islet transplant in diabetic mice
4. These shells dont clam up: Innovative technique to record human impact on coastal waters
5. Einstein researchers develop technique to count messages made by single genes
6. These shells dont clam up: Innovative technique to record human impact on coastal waters
7. Novel technique for fluorescence tomography of tumors in living animals
8. New edition of laboratory manual includes cutting-edge techniques to study gene regulation
9. New technique is quantum leap forward in understanding proteins
10. Novel technique changes lymph node biopsy, reduces radiaiton exposure
11. Novel technique changes lymph node biopsy, reduces radiation exposure
Post Your Comments:
(Date:10/26/2015)... LAS VEGAS , Oct. 26, 2015 /PRNewswire/ ... innovator in modern authentication and a founding member of ... of its latest version of the Nok Nok™ S3 ... use standards-based authentication that supports existing and emerging methods ... is ideal for organizations deploying customer-facing applications that require ...
(Date:10/23/2015)... Oct. 23, 2015 Research and Markets ( ... "Global Voice Recognition Biometrics Market 2015-2019" report to ... --> The global voice recognition biometrics market to ... --> --> The ... prepared based on an in-depth market analysis with inputs ...
(Date:10/22/2015)... (NASDAQ: AWRE ), a leading supplier of biometrics software and ... 30, 2015.  --> --> ... decrease of 33% compared to $6.0 million in the same quarter ... $2.2 million, or $0.10 per diluted share, which compared to $2.6 ... year ago.  --> --> ...
Breaking Biology News(10 mins):
(Date:11/24/2015)... Nov. 24, 2015 /PRNewswire/ - Aeterna Zentaris Inc. (NASDAQ: ... on behalf of the Toronto Stock Exchange, confirms that ... are no corporate developments that would cause the recent ... --> --> About Aeterna Zentaris Inc. ... --> Aeterna Zentaris is a specialty biopharmaceutical ...
(Date:11/24/2015)... ... 24, 2015 , ... This fall, global software solutions leader SAP and AdVenture ... develop and pitch their BIG ideas to improve health and wellness in their schools. ... to win the title of SAP's Teen Innovator, an all-expenses paid trip to Super ...
(Date:11/24/2015)... November 24, 2015 --> ... research report released by Transparency Market Research, the global ... a CAGR of 17.5% during the period between 2014 ... - Global Industry Analysis, Size, Volume, Share, Growth, Trends ... prenatal testing market to reach a valuation of US$2.38 ...
(Date:11/24/2015)... 2015  Twist Bioscience, a company focused on ... Twist Bioscience chief executive officer, will present at ... 1, 2015 at 3:10 p.m. Eastern Time at The Lotte ... --> --> About ... is on Twitter. Sign up to follow our ...
Breaking Biology Technology: