Navigation Links
New neural pathway controlling skeletal development discovered
Date:9/4/2012

Jerusalem, Sept. 3, 2012 Researchers at the Hebrew University of Jerusalem have discovered that a neuronal pathway -- part of the autonomic nervous system -- reaches the bones and participates in the control of bone development.

The newly discovered pathway has a key role in controlling bone density during adolescence, which in turn determines the skeletal resistance to fracture throughout one's entire life, say the researchers. They emphasize that understanding the mechanisms connecting the brain and the bones could have implications for possible future therapies to better deal with osteoporosis and various neural disorders.

The findings of the Hebrew University team are published this week in the American journal PNAS (Proceedings of the National Academy of Sciences).

Participants in the project were researchers from the Hebrew University's Bone Laboratory, headed by Prof. Itai Bab, in collaboration with Prof. Raz Yirmia, the head of the Laboratory for Brain and Behavioral Research, plus research students Alon Bajayo and Vardit Kram and master's students Arik Bar and Marilyn Bachar. Additional collaborators were Dr. Adam Denes from the University of Manchester, UK, and Prof. Alberta Zallone from the University of Bari, Italy.

The autonomic nervous system, by which the brain monitors and regulates the physiological functioning of the internal organs, includes two subsystems, called "sympathetic" and "parasympathetic." Each of these subsystems has its own, distinct neural pathways. In general, the sympathetic nervous system is perhaps best known for mediating the neuronal and hormonal responses to stress. The sympathetic pathway, on the other hand, generally works to promote maintenance of the body at rest.

Previous studies by the Hebrew University researchers and others showed that the sympathetic nervous system reaches the skeleton and slows down bone development. On the other hand, until now, th
'/>"/>

Contact: Jerry Barach
jerryb@savion.huji.ac.il
972-258-82904
The Hebrew University of Jerusalem
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Astrocytes control the generation of new neurons from neural stem cells
2. Novel microscopy method offers sharper view of brains neural network
3. Color-coded markers may help doctors diagnose neural diseases through the eyes
4. Transgenic technique to eliminate a specific neural circuit of the brain in primates
5. Manipulation of a specific neural circuit buried in complicated brain networks in primates
6. Cracking the Neural Code: Third Annual Aspen Brain Forum
7. Neural stem cell transplants for spinal cord injury maximized by combined, complimentary therapies
8. Scientists find neural stem cell regulator
9. Fragile X and Down syndromes share signalling pathway for intellectual disability
10. Cleveland Clinic researchers receive $5 million grant to discover novel pathways to heart disease
11. Study identifies pathway to enhance usefulness of EGFR inhibitors in lung cancer treatment
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New neural pathway controlling skeletal development discovered
(Date:8/27/2014)... belief that a deficiency in serotonin a chemical ... in depression. In the journal ACS Chemical Neuroscience ... make serotonin in their brains (and thus should have ... symptoms. , Donald Kuhn and colleagues at the ... University School of Medicine note that depression poses a ...
(Date:8/27/2014)... abandoned each year in U.S. waters and become what ... fish, crabs, and other species such as turtles. These ... watermen who depend on the resources--losses that are largely ... The report, published in the Marine Pollution Bulletin ... the derelict fish trap problem, and so-called "ghost fishing," ...
(Date:8/27/2014)... of studies have shown that excessive iron ... Parkinson,s disease. Previous studies from Chunyan Guo ... China have shown that baicalin prevented iron ... metal transporter 1 expression, and increased ferroportin ... rotenone-induced Parkinson,s disease rats. However, the relationship ...
Breaking Biology News(10 mins):New study throws into question long-held belief about depression 2NOAA's Marine Debris Program reports on the national issue of derelict fishing traps 2
... 9, 2013 With fierce competition and ... specialists need to increase efficiency continually. CRMATCH presents an ... for organisations keen to stay abreast of developments in ... grapple with ever-increasing amounts of complex data, and rise ...
... of American Societies for Experimental Biology (FASEB) is proud to ... Winning entries were unveiled on FASEB,s web site and ... of Health main campus. "The competition provides a glimpse into ... FASEB President Margaret K. Offermann, MD, PhD. "The winning images ...
... pieced together as an elaborate molecular jigsaw involving around 30 ... it is only made by certain bacteria. In the early ... allow its construction one that requires oxygen and one ... so-called anaerobic pathway, which is the more common pathway, that ...
Cached Biology News:Most Efficient Matching in Recruitment With CRMATCH and ELISE 2FASEB announces BioArt image and video competition winners 2
(Date:8/27/2014)... , Aug. 27, 2014 Tris Pharma, a ... technologies, today announced that it has been selected as ... Industry Association,s 2014 Awards for Excellence competition ... an independent panel of judges from SCORE (Counselors to ... winners will be honored at a gala event to ...
(Date:8/27/2014)... BIOEQUA, an innovative line of skin care ... handheld spray, has made its EQUA ESSENTIAL line available ... brand began with an unexpected discovery in an emergency ... that the application of nanospray technology allowed for liquid ... to skin's basal layer. This resulted in immediate absorption ...
(Date:8/27/2014)... White City, OR (PRWEB) August 27, 2014 ... Supply Report, “Consolidation continues to reshape the look and ... in nutrition. Consumer demand for higher-quality ingredients will push ... the North American market have experienced strong market growth ... and ethical attributes in their food and cosmetics to ...
(Date:8/27/2014)... WriteResult, LLC – a premier provider of ... superiority when it comes to meeting the needs of ... of their most recent study closeout on-time and with ... digital writing platform to collect Patient Reported Outcomes electronically ... drew data from a number of assessments including the ...
Breaking Biology Technology:Tris Pharma Selected as an award winner in the New Jersey Business & Industry Association's 2014 Awards for Excellence 2BIOEQUA'S EQUA ESSENTIAL Product Line Redefines Skin Care & Now Available in America 2Daring to be Different Raw Materials & Ingredient Supply Shortage Fuels Vital Force™ Technology New Ingredient Enhancements 2Daring to be Different Raw Materials & Ingredient Supply Shortage Fuels Vital Force™ Technology New Ingredient Enhancements 3A Perfect Record: WriteResult Maintains a 100% On-Time ePRO Record with Latest Irritable Bowel (IBS) Study Data Lock 2
... Barr,Pharmaceuticals, Inc. (NYSE: BRL ) today announced that ... U.S. Food & Drug,Administration (FDA) to manufacture and market ... hydrobromide extended release,capsules), eq. to 8 mg, 16 mg ... the,first company to file an Abbreviated New Drug Application ...
... Receives $1.1 Million to Investigate Innocence Claims, ... (DOJ) today announced over $1.1 million to the ... reviewing cases where DNA testing and,evidence may prove ... Justice,Programs (OJP), the funding is one of five ...
... ProSource 2.0 is a customized lab supply ordering system ... of every lab supply they currently order. ProSource then ... prices to ensure savings on every order. ProSource eliminates ... lab in your company to order from the same ...
Cached Biology Technology:Barr Receives Approval for Generic Version of Razadyne(R) ER Capsules 2Barr Receives Approval for Generic Version of Razadyne(R) ER Capsules 3Barr Receives Approval for Generic Version of Razadyne(R) ER Capsules 4Barr Receives Approval for Generic Version of Razadyne(R) ER Capsules 5Department of Justice Provides States With Funding for Testing in Postconviction Cases 2ProSource 2.0 Offers Value, Savings for Lab Supplies 2
E2F2 protein...
Rabbit Anti-melatonin (different linkage) Polyclonal Antibody...
... to Cholesterol Oxidase Immunogen Cholesterol ... Cross-reacts with bacteria. Not yet tested in ... oxidases exist as both type I and ... bacterial pathogenesis. In addition, they are important ...
Phospho-PERK (Thr980) Antibody...
Biology Products: